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Twist Bioscience has a GC variance constraint. Quote from their website:
> Avoid extreme differences in GC content within a gene (i.e. the difference in GC content between the highest and lowest 50…
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As part of the request "Better/more obvious integration of "validated" structure annotations from sandbox/glycotree" from the F2F, @edwardsnj will look into the validation logic in glycotree. Afterwar…
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This si a spin of from #6 for the additions of general linear constraints of the form:
`C * v relation d`
Where `C` is a matrix with columns corresponding to model reactions and rows corresponding t…
tpfau updated
6 years ago
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Hi,
Thanks a lot for the wonderful work. I noticed that 'covalent modification' is [possible](https://www.chaidiscovery.com/blog/introducing-chai-1#:~:text=covalent%20modifications) to predict usin…
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#### Current behavior:
31 genes are discovered to be uncorrelated with their corresponding reactions in `Miscellaneous`, `Isolated` and `Drug metabolism`.
| Gene| UniProtID| Reaction| GPR|…
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As discussed on slack, I am sharing an MWE to reproduce the issues with some backends on the GPU that I hit. I believe that most of these failures are very representative of the failures that I have s…
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I would like to suggest replacing the boolean representation of GPR associations with a true Gene-Protein-Reaction association schema.
Here are few reasons for this:
1. Gene expression is not bo…
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Code:
```julia
import ADTypes, DifferentiationInterface, Enzyme
Enzyme.API.runtimeActivity!(true)
broadcast(
x -> sum(
DifferentiationInterface.pushforward(
x -> vca…
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Optimization.jl is okay, but it's not quite conforming to the standards of the SciML interface.
It conflaits the "solver package" with the "interface package". In some sense, the current
Optimizatio…
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Is this purely web or is there any hope for making native (specifically React Native) application demos with it? What's a birds-eye-overview of what would need to be done to record native application …