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Hi,
I was wondering if you considered using syncmers (I believe it's already implemented in minimap2) to map the genes between different species? I believe synmcers are specifically meant for highe…
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Hey it's me again :) I briefly corresponded with @ksahlin on a refined version of closed syncmers with 25-30% lower density for realistic values of k. This might be useful for strobealign.
 to hash syncmers.
We could switch to a different, fa…
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### Background
Randstrobes is a method for linking two or more k-mers together into a seed that can be used for sequence mapping. I intend the below post to be a self-contained rough description of…
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Dear Wei Shen,
I really like your tool and your tutorials. I just have a question regarding long read metagenomic profiling. Is there a specific parameter combination you would recommend to use to ta…
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In the following data: [data.tar.gz](https://github.com/user-attachments/files/16457383/data.tar.gz)
there is exactly one single-end short read in `input.fasta` and two sets of haplotypes, `full.fa.g…
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Hi @eric9n,
I open an additional issue here about using a different sketching algorithm, in addition to minimizer. I attached slide explaining the differences between minimizer and open syncmer and…
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Hi,
I get the following error when running miniprot looking for 200 proteins at a 73MB genome:
[M::mp_ntseq_read@0.375*1.01] read 68163509 bases in 69053 contigs
[M::mp_idx_build@0.379*1.01] 608218…
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## Question
Hi Seqan-Team,
I just recently read about XOR Filters and that they were superior to Bloom Filters in regards to memory usage and query time. Do you plan (or maybe already started) t…