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Advanced Normalization Tools (ANTs)
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Multi modal template creation optimizing for both brain tissue and none brain tissues! #1583

Open roohy466 opened 1 year ago

roohy466 commented 1 year ago

I need to create a template from the population using multimodal approaches something like this article. As I am using open source datasets like open-euro , all of them are defaced. therefore the template creation would be optimal on the brain tissues if I remove the skull, however I am also interested in optimizing the template for none brain tissues as I want to use those skull-muscles for normalization proposes! How do you solve this problem? Any help really appreciated

Best Rouhi

ntustison commented 1 year ago

Template creation is constrained by the requirement of having spatial correspondences across the population used to construct the template. We had a related issue in our cortical thickness paper where we were using multiple datasets each with their own defacing protocol. We also needed the non-brain tissue for normalization purposes so we ended up creating multiple templates ANTs templates. In your case, you might have to do something similar, especially if you need it for normalization purposes.