Z expression matrix

[martina811]

Hello, I would like to know what is the step in Bayes Prism where the Z matrix, that we found in posterior.initial.state/type, is generated?

Thanks a lot for your help

[tinyi]

Hi. I wasn’t quite sure I understand your question. Could you elaborate a bit?

On Wed, Nov 29, 2023 at 19:10 biomart811 @.***> wrote:

Hello, I would like to know what is the step in Bayes Prism where the Z matrix, that we found in posterior.initial.state/type, is generated?

Thanks a lot for your help

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[martina811]

I am using Bayes Prism, and I want to use it as a tool for having a measure of confidence of my results. So I was wondering if I can extract the posterior probability on which bayes prism based its results in θf.

[tinyi]

Hi. BayesPrism reports the coefficient of variation for the posteriors theta0 and thetaf, but does not report this for Z, mainly due to consideration of computational and memory efficiency.

On Wed, Dec 13, 2023 at 22:21 biomart811 @.***> wrote:

I am using Bayes Prism, and I want to use it as a tool for having a measure of confidence of my results. So I was wondering if I can extract the posterior probability on which bayes prism based its results in θf.

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[martina811]

And there is a way to calculate the posterior probability that bayes prism use for update thetaf starting from theta0 ? Thank you

[tinyi]

Not sure if I understand the question. For the exact math, please refer to the BayesPrism manuscript. For the code, please refer to the update_reference.R .

On Thu, Dec 14, 2023 at 5:36 PM biomart811 @.***> wrote:

And there is a way to calculate the posterior probability that bayes prism use for update thetaf starting from theta0 ? Thank you

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[martina811]

my question is if from Bayes Prism there is a way to obtain a measure of confidence for the updated thetaf that Bayes Prism provides.

[tinyi]

please refer to the vignette tutorial_deconvolution.html

extract coefficient of variation (CV) of cell type fractiontheta.cv

<- @.**@.

On Thu, Dec 14, 2023 at 5:47 PM biomart811 @.***> wrote:

my question is if from Bayes Prism there is a way to obtain a measure of confidence for the updated thetaf that Bayes Prism provides.

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