DyogenIBENS / Agora

Algorithm For Gene Order Reconstruction in Ancestors
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how prepare input files for Regulus #2

Closed yuzhenpeng closed 2 years ago

yuzhenpeng commented 3 years ago

Dear, teams

Recent, I have read your articles which published on nature communication (in 2015) and nucleic acids research (in 2020).

As you said in paper "Linking long distance regulatory regions to the genes they regulate is important to study and understand the function of enhancers. Three main categories of experimental methods have been developed to assign enhancers to target genes in a genome-wide manner. The use of methods based on evolutionary principles could solve these difficulties, because they do not depend on the specific biological contexts required by experimental assays and are more easily applicable to multiple species"

Regulus is a wonderful tools to predict the target genes of regulatory elements.

I want use your tools for my research. But, because I don't know exactly how many input files are generated, and what each row and column of the output results represent. So I can't make good use of the tools you developed.

If you can provide more detailed documentation, this may be more conducive to the use and development of software.

Would you mind share the steps for preparing input files for anyone.

Thank you very much.

@DyogenIBENS @JosephLucas @alouis72