Split chromosomes for calling variant like gatk.

HKU-BAL / Clair3

Clair3 - Symphonizing pileup and full-alignment for high-performance long-read variant calling

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Split chromosomes for calling variant like gatk. #301

Closed RADIOMUMM closed 7 months ago

RADIOMUMM commented 7 months ago

Is it possible for Clair3 to use the BAM files split by chromosome for calling variant separately and finally merge the resulting VCF files to reduce the run time? Or is there any other way to reduce the runtime?

aquaskyline commented 7 months ago

Clair3 do splitting into 5Mbp chucks for parallel processing by default.