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MannLabs / alphadia

modular & open DIA search
https://alphadia.readthedocs.io
Apache License 2.0
55 stars 3 forks source link

dia-PASEF format #379

Open Li5459000 opened 3 days ago

Li5459000 commented 3 days ago

Hi,

"Alltough search is possible, alphaDIA's feature-free search takes a long time with fully predicted libraries."

If speed is not a concern, would using library free search for dia-PASEF format compromise analytical performance, such as resulting in lower IDs?

Li5459000 commented 1 day ago

How should I specify modifications beyond the default ones? I am using the GUI, but there doesn't seem to be a list of selectable modifications.

For example, if I want to set Methionine excision (N-term), how should I configure it?

Thank you in advance.