Add enzymes needed for DDI between Efavirenz and Carbamazepine to individual

Open-Systems-Pharmacology / Carbamazepine-Model

PBPK model of carbamazepine as CYP3A4 and CYP2B6 substrate and inducer

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Add enzymes needed for DDI between Efavirenz and Carbamazepine to individual #10

Closed AndreDlm closed 10 months ago

AndreDlm commented 10 months ago

The enzymes CYP1A2, CYP2A6, and CYP3A5 in the individual Ji 2008 are required for the DDI simulations between Efavirenz and Carbamazepine and should be added to execute the qualification plan