Open-Systems-Pharmacology Forum issues

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VENLAFLAXINE PBPK Project

#652 harishkaushikbugworks closed 3 years ago
1
How to input particle size distribution measurements measurements in PK-sim?

#639 tobiasK2001 closed 3 years ago
16
How to simulate the effect of food on drugs?

#638 Wenjing1018 closed 3 years ago
14
Protein and transporters in salivary glands

#637 2Dinh-Bui closed 3 years ago
0
Change in albumin concentration

#636 AParisotto closed 3 years ago
1
Simulation fails because of getting negative concentrations

#635 mmalsmadi closed 3 years ago
14
How can I find the course to learn about the PK-sim software

#634 Zhaowenyu-gaga closed 3 years ago
4
Decreased values when exported to excel

#633 AParisotto closed 3 years ago
3
Renal and Hepatic Specific CL.

#632 Vichelfer closed 4 years ago
2
Kinetic constants of an enzyme in reversible drug metabolism

#631 shapoo1 closed 3 years ago
5
Interstitial:plasma partition coefficients are the same for all organs, but intracellular:plasma are different. Why?

#630 eburg007 closed 4 years ago
2
How to simulate intermittent dialysis?

#629 yishuanwu closed 3 years ago
5
Published: A workflow to build PBTK models for novel species

#628 Yuri05 closed 3 years ago
0
Batch processing in PK-Sim and MoBi

#627 yvkashyap closed 4 years ago
2
Pathway contribution to total body clearance

#626 harridickinson closed 3 years ago
7
Total Amount in Organism

#625 DonkeySaddle closed 4 years ago
5
Scaling parameters from adult to pediatrics

#624 faisalhhu closed 3 years ago
9
How to run PBPK model to simulate drug concentration of a real patient (using CLI)

#623 lamnvcnsh closed 3 years ago
3
Peptide in PK-SIM

#622 Boulenc closed 3 years ago
2
Creating DDI of the drug

#621 Esther806 closed 3 years ago
5
New to PBPK modeling

#619 pburkat closed 3 years ago
9
Partition coefficient water/protein for tissue distribution model

#618 andanteyang closed 3 years ago
0
Physiologically-Based Pharmacokinetic (PBPK) Modeling of Fentanyl in Adults and Pediatric Patients

#617 LkKov closed 3 years ago
1
Handling Lipoprotein Binding

#616 StephanSchaller closed 3 years ago
0
Changes of renal clearance rate in elderly

#615 Wenjing1018 closed 3 years ago
2
Which parameters are modified to bulid renal insufficiency model?

#614 Wenjing1018 closed 3 years ago
6
Simulation tab closes after re-configuring the simulation

#613 PavelBal closed 4 years ago
3
How to calculate the GMFE?

#612 andanteyang closed 3 years ago
1
Confidence interval_PK-Sim

#611 2Dinh-Bui closed 3 years ago
0
Add Metabolizing Enzyme...（Database not available）

#610 N-S-cbW closed 3 years ago
2
Where to find the equation of degree of charge in subcompartments and Partition coefficients

#609 PriKalra closed 4 years ago
2
Added link to the documentation.

#608 PavelBal closed 4 years ago
1
metabolite formation

#607 Nathalie06 closed 3 years ago
6
installing MoBI 7.3

#606 praveenniper closed 3 years ago
2
How to set up Parent-Metabolite Model

#605 humblewarrior closed 4 years ago
1
Tissue concentration

#604 Ricardo-DO closed 3 years ago
5
PK-SIM permeability-SA products etc?

#603 jmgallo closed 3 years ago
2
Hepatic impairment population

#602 Nathalie06 closed 3 years ago
2
Can I insert my dissolution data into PK-Sim?

#601 Esther806 closed 3 years ago
3
Where can I download models created by older versions of PKsim in Model Library

#600 andanteyang closed 3 years ago
1
How to install OSPSuite-Full.9.1.3 in MacBook Pro

#599 praveenniper closed 3 years ago
3
Partition Coefficients (PCS) Definition?

#598 jmgallo closed 3 years ago
3
How to make the goodness of fit plot

#597 Wenjing1018 closed 3 years ago
3
Kp Sclar value

#596 humblewarrior closed 4 years ago
3
Question regarding removing subjects in simulation and chart settings

#595 humblewarrior closed 4 years ago
7
predicted concentration vs observed concentration

#594 Wenjing1018 closed 3 years ago
7
Role and localization of P-gp in lungs

#593 Nathalie06 closed 3 years ago
4
How to define parameter variability？

#592 Wenjing1018 closed 3 years ago
2
How to import a large dataset?

#591 humblewarrior closed 4 years ago
2
Partition coefficient (water/container) reference to Partition coefficient (interstitial/water)

#590 wilbertdew closed 3 years ago
5

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