AMR Annotation Modules (Option 2)
We will update the existing k-mer-based annotation software in PATRIC/RAST in order to propagate AMR-related annotations from ARDB, CARD, Resfams, and the manual annotations from AMR Curation (Option 1). We will build and deploy software that enables the direct propagation of AMR-related functions from a reference genome to a closely related strain. This will be deployed in the annotation application that is available on the PATRIC website. Propagation will be enabled for well-studied organisms at first (e.g., Escherichia coli and Mycobacterium tuberculosis), and will be expanded, as PATRIC annotations are reconciled with the reference genome annotations from the
community.
AMR Annotation Modules (Option 2) We will update the existing k-mer-based annotation software in PATRIC/RAST in order to propagate AMR-related annotations from ARDB, CARD, Resfams, and the manual annotations from AMR Curation (Option 1). We will build and deploy software that enables the direct propagation of AMR-related functions from a reference genome to a closely related strain. This will be deployed in the annotation application that is available on the PATRIC website. Propagation will be enabled for well-studied organisms at first (e.g., Escherichia coli and Mycobacterium tuberculosis), and will be expanded, as PATRIC annotations are reconciled with the reference genome annotations from the community.