TranslatorSRI / Babel

Babel creates cliques of equivalent identifiers across many biomedical vocabularies.
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MESH:C053590 (quinquefolan B) is combined with CHEBI:16335 (adenosine) #364

Open gaurav opened 1 month ago

gaurav commented 1 month ago

Confirmed on NodeNorm Dev.

The connections here appear to be:

concords/mesh_cas:MESH:C053590  xref    CAS:109767-06-8
concords/PUBCHEM_CAS:PUBCHEM.COMPOUND:60961 xref    CAS:109767-06-8
concords/CHEBI:CHEBI:16335  xref    PUBCHEM.COMPOUND:60961

concords/PUBCHEM_CAS is generated from the "Depositor Supplied Synonyms" of PUBCHEM.COMPOUND:60961 "Adenosine", so that's where that connection comes from.

However, note that CAS:109767-06-8 "quinquefolan B" has "Adenosine" as the chemical name, has exactly the same chemical formula as PUBCHEM.COMPOUND:60961 "Adenosine", but has a slightly different IUPAC name: ID IUPAC name
PUBCHEM.COMPOUND:60961 (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
CAS:109767-06-8 (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

So I think we'll need a chemist to figure out if this needs to be split (and -- if so -- it'll be easier to complain to PubChem about it rather than trying to fix it within Babel.)

colleenXu commented 1 month ago

"quinquefolan B" seems to be the name of a Polysaccharide glycans extracted from American ginseng though...

Looking up this name from Duckduckgo: