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Pregabalin + Tramadol #56

Closed utaninja closed 7 months ago

utaninja commented 7 months ago

Pregabalin + Tramadol

Dangerous

At higher dosages, the combination increases the risk of seizures. Central nervous system and/or respiratory-depressant effects may be additively or synergistically present.

https://pubmed.ncbi.nlm.nih.gov/22814011/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688538/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755854/ https://www.mdpi.com/1424-8247/15/10/1254 https://www.sciencedirect.com/science/article/abs/pii/S0002934318304029 https://www.tandfonline.com/doi/full/10.1080/24734306.2018.1458465#:~:text=Toxicity%20may%20occur%20after%20overdose,seizure%20with%20confirmatory%20serum%20concentrations https://www.fda.gov/media/133681/download https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919607/ https://link.springer.com/article/10.1007/s11419-020-00569-0 https://www.tandfonline.com/doi/full/10.3109/15563650.2015.1036279

utaninja commented 7 months ago

This is going to be temporarily closed until further discussion on Pregabalin. Will be posting a discussion about this soon.