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YiPeng-Gao / scDaPars

Dynamic Analysis of Alternative Polyadenylation from single-cell RNA-seq (scDaPars)
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confounding factor #6

Closed BenxiaHu closed 3 years ago

BenxiaHu commented 3 years ago

Hello, For example, I have 2 scRNAseq datasets (AD and control), each consisting of 10 samples. But each sample has some different features, such as age and sex. When we analyze differential expression for such bulk RNAseq or scRNAseq, we usually regress out these possible confounding factors(age and sex). my question is that DaPars or scDaPars regresses out those confounding factors?

YiPeng-Gao commented 3 years ago

Currently we do not regress out confounding factors.