Hi, I was wondering if there is a way to have a safety filter in silico to be sure that the generated protein sequence with ProteinMPNN is "safe" to use. For example that it is not a toxin, a prion or a cell penetrating peptide?
Do you think a simple blast would be sufficient?
Are there better tools available (AI based or not) to safely design proteins sequences?
Hi, I was wondering if there is a way to have a safety filter in silico to be sure that the generated protein sequence with ProteinMPNN is "safe" to use. For example that it is not a toxin, a prion or a cell penetrating peptide? Do you think a simple blast would be sufficient? Are there better tools available (AI based or not) to safely design proteins sequences?