Announcements related to ontology changes that may impact groups using GO, such as obsoletions, merges, etc.
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Obsoletion notice: GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator and related terms (with replacements) #886
The proposal has been made to obsolete
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator -> GO:0030330 DNA damage response, signal transduction by p53 class mediator
GO:1902163 negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator -> GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:1902162 negulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator -> GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator
GO:1902164 positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator -> GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest -> GO:0030330 DNA damage response, signal transduction by p53 class mediator
The reason for obsoletion is that these terms are about down stream effects, not the signaling pathway itself.
There are 50 experimental annotations to this term by
BHF-UCL 2
CAFA 5
HGNC-UCL 1
MGI 7
PINC 1
Reactome 8
UniProt 25
ZFIN 1
Reactome has fixed one, the rest should be automatically transferred.
There are no mappings to this term.
This term is not present in any subset.
Dear all,
The proposal has been made to obsolete GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator -> GO:0030330 DNA damage response, signal transduction by p53 class mediator GO:1902163 negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator -> GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator GO:1902162 negulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator -> GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator GO:1902164 positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator -> GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest -> GO:0030330 DNA damage response, signal transduction by p53 class mediator
There are 50 experimental annotations to this term by BHF-UCL 2 CAFA 5 HGNC-UCL 1 MGI 7 PINC 1 Reactome 8 UniProt 25 ZFIN 1
Reactome has fixed one, the rest should be automatically transferred.
There are no mappings to this term. This term is not present in any subset.
Annotations can be viewed here: https://github.com/geneontology/go-annotation/issues/5545.
These terms are being replaced by (terms to the right of arrows).
Any comments can be added to the issue:https://github.com/geneontology/go-ontology/issues/26003.
Thanks,
The GO-Ontology Editors