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Source ontology files for the Gene Ontology
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meiotic recombination #11185

Closed gocentral closed 9 years ago

gocentral commented 10 years ago

I would like to describe a meiotic recombination process, but it is occurring between sister chromatids.

I can only find:

GO:0007131 reciprocal meiotic recombination

Ontology Biological Process Definition The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material ** between non-sister chromatids in a pair of homologous chromosomes*. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.

which only specifies homologous chromosomes

and is tagged with

Is there, or can there be a more general meiotic recombination term with children?

Name This term is located in a node of the Gene Ontology where there are active ontology discussions. Please refer to the 'GO Discussions' tab for more information.

Reported by: ValWood

Original Ticket: geneontology/ontology-requests/11002

gocentral commented 10 years ago

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 I would like to describe a meiotic recombination process, but it is occurring  between sister chromatids.

Original comment by: jl242

gocentral commented 10 years ago

a bit of additional info: Val's curating PMID:20123974, which describes "unequal sister chromatid recombination" (USCR) and "intrachromatid recombination" (ICR).

We're not sure if these are normal processes, but it looks like GO ought to include something about recombination between chromatids during meiosis, and/or about regulating whether recombination is within a chromatid, between sister chromatids, or between homologous chromosomes.

Original comment by: mah11

gocentral commented 10 years ago

Diff:


--- old
+++ new
@@ -1,4 +1,3 @@
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 I would like to describe a meiotic recombination process, but it is occurring  between sister chromatids.

 I can only find:

Original comment by: ValWood

gocentral commented 9 years ago

Original comment by: jl242

gocentral commented 9 years ago

Original comment by: ValWood

gocentral commented 9 years ago

Decided as it isn't clear whether these are normal processes not to make this this term right now. If we need new terms request in new tickets. GO has no experts in recombination, and this node probably needs a larger overhaul, would need to recruit help.

Original comment by: ValWood