Hello, I do have an unbalanced number of replicates for my conditions. Can I read these unbalanced numbers of replicates as one, say, one condition A has 5 replicates and the other B has 3 replicates? Use these conditions A and B as pooled data, so I run the analysis as A and B to compare methylation between these groups. will DSS handle this kind of bias?
Hello, I do have an unbalanced number of replicates for my conditions. Can I read these unbalanced numbers of replicates as one, say, one condition A has 5 replicates and the other B has 3 replicates? Use these conditions A and B as pooled data, so I run the analysis as A and B to compare methylation between these groups. will DSS handle this kind of bias?