Error accessing resource on Dropbox cram

[aardes]

Dear,

Recently I have issue with loading CRAM files through the online version, File is loaded correctly but when I search for a position it gives me the following error:

Error accessing resource: https://dl.dropboxusercontent.com/********.cram Status: 0

I tried an old version of the javascript code locally as well as the IGV application and the link is correct and I am able to load my cram file and search for the position.

May I kindly ask you to look into this issue?

Thanks in advance Amin

[jrobinso]

Hi, I can't reproduce the issue. Here is my test CRAM, for hg19, jump to gene SLC25A3

cram: https://www.dropbox.com/s/sk1d88s54v06n6u/heart_slc25a3.cram?dl=0 index: https://www.dropbox.com/s/3ngrv2qsrrr07bo/heart_slc25a3.crai?dl=0

Could you share a link to a CRAM file that is giving you an issue?

[aardes]

Dear Jim,

Thanks for the fast response, may I have your email address?

Regards

[aardes]

and for your info, I tried different browsers and for the link you shared, I see the exact same error.

[jrobinso]

That doesn't look like the webapp (igv.org/app), so I can't really tell what you are using. Can you try it at https://igv.org/app?

If you need to send a link to private data you can send it to igvteam (at) broadinstitute.org

[aardes]

Please have the full screenshot, I am using the igv app.

I've just noticed that it's related to the browser, I tried google chrome and it's working, Safari and Firefox generate this error.

[jrobinso]

Ahh, important detail. We'll look into it. You say it does work in older versions of igv.js? What is the latest version you have seen it working?

[aardes]

I have the v1.6.3 in my application and working, before updating to the new version I perform a couple of tests and at the beginning, I thought that it's on my side but then I saw the web app also have the same issue.

[jrobinso]

We do not have a release tagged v1.6.3. Where did you get this from?

[helgathorv]

@aardes Did you mean v1.6.3 of the IGV-Web App? When I install that version, I see the same problems (ie works in Chrome and not in Safari/Firefox)

[jrobinso]

Sorry my mistake, I thought the reference was to igv.js version number. I can't find any version of igv.js going back to version 2.0.0 (2018) that works with Firefox+dropbox.

[jrobinso]

BTW Firefox+dropbox most definitely worked at some point in the past, something changed either at Dropbox or with the browsers. I filed an issue at Dropbox, unless and until they respond there isn't anything we can do.

https://www.dropboxforum.com/t5/Dropbox-installs-integrations/CORS-requests-involving-OPTIONS-preflight-failing-from-Firefox/m-p/582217/highlight/false#M118137

[aardes]

Thank a lot, I can understand. I will inform the users to use chrome.

[jrobinso]

I think this is fixed. It was a problem at Dropbox.

[jrobinso]

Hi,

Dropbox reports they have fixed the problem. We tested Safari and indeed it looks fixed.

On Tue, Mar 8, 2022 at 3:08 AM Amin Ardeshirdavani @.***> wrote:

Thank a lot, I can understand. I will inform the users to use chrome.

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