Couldn't run RawTools on Windows 7

[fazeliniah]

Hi, I get the following error message when I try to run RawTools. I appreciate any help. Thanks

C:\RawTools1.3.2>RawTools parse -f ch_23Aug2018_HeLa_Std_1.raw -x

Processing: ch_23Aug2018_HeLa_Std_1.raw

Unhandled Exception: System.TypeInitializationException: The type initializer fo r 'ThermoFisher.CommonCore.Data.Business.RawFileReaderFactory' threw an exceptio n. ---> System.IO.FileLoadException: ThermoFisher.CommonCore.RawFileReader.dll i s not found in C:\Users\Owner\Downloads\RawTools1.3.2 ---> System.IO.FileLoadExc eption: Could not load file or assembly 'file:///C:\Users\Owner\Downloads\RawToo ls1.3.2\ThermoFisher.CommonCore.RawFileReader.dll' or one of its dependencies. O peration is not supported. (Exception from HRESULT: 0x80131515) ---> System.NotS upportedException: An attempt was made to load an assembly from a network locati on which would have caused the assembly to be sandboxed in previous versions of the .NET Framework. This release of the .NET Framework does not enable CAS polic y by default, so this load may be dangerous. If this load is not intended to san dbox the assembly, please enable the loadFromRemoteSources switch. See http://go .microsoft.com/fwlink/?LinkId=155569 for more information. --- End of inner exception stack trace --- at System.Reflection.RuntimeAssembly._nLoad(AssemblyName fileName, String cod eBase, Evidence assemblySecurity, RuntimeAssembly locationHint, StackCrawlMark& stackMark, IntPtr pPrivHostBinder, Boolean throwOnFileNotFound, Boolean forIntro spection, Boolean suppressSecurityChecks) at System.Reflection.RuntimeAssembly.InternalLoadAssemblyName(AssemblyName as semblyRef, Evidence assemblySecurity, RuntimeAssembly reqAssembly, StackCrawlMar k& stackMark, IntPtr pPrivHostBinder, Boolean throwOnFileNotFound, Boolean forIn trospection, Boolean suppressSecurityChecks) at System.Reflection.RuntimeAssembly.InternalLoadFrom(String assemblyFile, Ev idence securityEvidence, Byte[] hashValue, AssemblyHashAlgorithm hashAlgorithm, Boolean forIntrospection, Boolean suppressSecurityChecks, StackCrawlMark& stackM ark) at System.Reflection.Assembly.LoadFrom(String assemblyFile) at ThermoFisher.CommonCore.Data.ObjectFactory1.Initialize(Boolean throwExcep tions) --- End of inner exception stack trace --- at ThermoFisher.CommonCore.Data.ObjectFactory1.Initialize(Boolean throwExcep tions) at ThermoFisher.CommonCore.Data.Business.RawFileReaderFactory.CreateReader() at ThermoFisher.CommonCore.Data.Business.RawFileReaderFactory..cctor() --- End of inner exception stack trace --- at ThermoFisher.CommonCore.Data.Business.RawFileReaderFactory.ReadFile(String fileName) at RawTools.Program.DoStuff(ParseOptions opts) in C:\Users\Kevin\Documents\GS C\Projects\RawTools\RawTools\Program.cs:line 329 at CommandLine.ParserResultExtensions.WithParsed[T](ParserResult1 result, Ac tion1 action) at RawTools.Program.Main(String[] args) in C:\Users\Kevin\Documents\GSC\Proje cts\RawTools\RawTools\Program.cs:line 63

[kevinkovalchik]

Hello,

Thanks for bringing up the issue. I think windows might be blocking the file, though I'm not sure. This isn't something we have encountered, but we haven't done much testing on Windows 7.

Try this:

1. Right click on RawTools.exe and go to Properties
2. At the bottom of the window next to Security, if it says something about the application being blocked, click on the Unblock button.

If that doesn't work, see if there is a similar option in the properties of the .dll files in the directory.

To be sure, is your .NET version 4.6.2 or greater?

Kevin

[fazeliniah]

Thanks for your quick reply. The ,NET version is 4.6.2 I did unblock all the files in the directory and ran it again. I get a shorter error message:

C:RawTools1.3.2>RawTools.exe parse -f ch_23Aug2018_HeLa_Std_1.raw -x

Processing: ch_23Aug2018_HeLa_Std_1.raw

Unhandled Exception: System.NullReferenceException: Object reference not set to an instance of an object. at ThermoFisher.CommonCore.RawFileReader.RawFileAccessBase.SelectInstrument(D evice instrumentType, Int32 instrumentIndex) at RawTools.Program.DoStuff(ParseOptions opts) in C:\Users\Kevin\Documents\GS C\Projects\RawTools\RawTools\Program.cs:line 333 at CommandLine.ParserResultExtensions.WithParsed[T](ParserResult1 result, Ac tion1 action) at RawTools.Program.Main(String[] args) in C:\Users\Kevin\Documents\GSC\Proje cts\RawTools\RawTools\Program.cs:line 63

[kevinkovalchik]

Hm. Well, that's some progress at least!

I can reproduce the error by giving it the name of a raw file that doesn't exist (which is something I should address as well). Can you try using the full path to the file after -f? It is supposed to work with just the filename, but maybe this is another Windows 7 thing we haven't found...

[KunathBJ]

Hello,

I've got the same errr on windows10 enterprise. Even with the full path and it doesn't seem to be blocked. So me I just have the long message, not the short one.

Thank you very much,

Benoit

[kevinkovalchik]

Hi Benoit,

Try replacing the RawTools.exe.config file with the following file:

RawTools.exe.txt

GitHub won't let me upload something with the extension .config, so I changed it to .txt. Be sure to change it back to .config, so it will be called RawTools.exe.config

If it is a security issue, which the error message seems to indicate, I think this will fix it. If it works I will make this a permanent change to the config file in the repository.

Kevin

[KunathBJ]

Hello,

It did fix it!! Very useful output!! Thanks a lot! Benoit

[kevinkovalchik]

Great! Thanks for letting me know. I'll make that a permanent change to the config file then.

Kevin

On Thu, Nov 22, 2018, 2:17 PM KunathBJ <notifications@github.com wrote:

Hello,

It did fix it!! Very useful output!! Thanks a lot! Benoit

— You are receiving this because you commented. Reply to this email directly, view it on GitHub https://github.com/kevinkovalchik/RawTools/issues/5#issuecomment-441127695, or mute the thread https://github.com/notifications/unsubscribe-auth/APT50MK72vD5gRjaXg3cJlWyxH5gGSetks5uxyJ5gaJpZM4YtxhH .

[kevinkovalchik]

@fazeliniah let me know if your issue wasn't resolved and we can reopen this.

Kevin

[aulke]

Hi Kevin, I am also having an issue running RawTools 1.4.2 version on my Win 10 Enterprise PC. RawTools ran just fine until just now. When I input in cmd i.e. C:\Users\aulke\Documents\RawTools-1.4.2>RawTools.exe parse -h, I get the error box in the attached file, as well as the message "Access is denied" in cmd.

I tried the tips from above: Changing RawTools.exe.config as well as "unblocking" all .dll files. I could not unblock the RawTools.exe file since I could not find an "unblock" tick box. As an interesting site: RawTools 1.4.1 works fine. So far, I could not find a solution and any help would be appreciated, Cheers, Anne

[kevinkovalchik]

Hm. The most obvious cause of this would be that your computer is running a 32-bit OS or has a x86 based processor... but I imagine that is not the case since v1.4.1 works fine.

There is very little difference between 1.4.1 and 1.4.2. I didn't change the target OS architecture or anything... Have you tried any of the compatibility modes in the program properties?

The only significant change in 1.4.2 that might cause the system to be unhappy is that the .NET cultural environment is forced to be "invariant" to prevent certain language settings from using comma decimals instead of dot decimals in the MGF file, as X!Tandem seems to have no idea what to do with them. Is your OS language set to something other than English? Possibly that combined with an over-zealous systems security might be causing the issue, but I really don't know...

[aulke]

I am running 64-bit operating system with x64-based processor. i7, 16GB ram. I have the .NET framework 4.7.2 (461808).