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mgijax / mammalian-phenotype-ontology

Standard terms for annotating mammalian phenotypic data
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abnormal circulating myoglobin level #3236

Closed anna-anagnostop closed 4 years ago

anna-anagnostop commented 4 years ago

Add new term: abnormal circulating myoglobin level (a child of abnormal circulating protein level MP:0005416) DEF: anomaly in the blood level of myoglobin, a low molecular weight oxygen binding heme protein that is normally found exclusively in heart and skeletal muscle cells; in blood, myoglobin is bound primarily to plasma globulins, a complex which is filtered by the kidneys; if the plasma concentration exceeds the plasma binding capacity, myoglobin begins to appear in the urine; monitoring myoglobin levels in blood (and urine) has been used as a means to detect skeletal or cardiac muscle cell injury SOURCE: ISBN:9780124157590

increased circulating myoglobin level DEF: increased blood level of myoglobin, a low molecular weight oxygen binding heme protein that is normally found exclusively in heart and skeletal muscle cells; in blood, myoglobin is bound primarily to plasma globulins, a complex which is filtered by the kidneys; if the plasma concentration exceeds the plasma binding capacity, myoglobin begins to appear in the urine; myoglobin is rapidly released into the bloodstream after muscle damage, and thus can be a useful biomarker in the early phases of heart or skeletal muscle injury SYN: elevated blood myoglobin level

anna-anagnostop commented 4 years ago

Added new terms:

abnormal circulating myoglobin level MP:0031107 increased circulating myoglobin level MP:0031108