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Repository for discussion of OpenSAFELY codelists
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*MEDICATION*: [NSAIDs] #306

Closed speed-vm closed 4 months ago

speed-vm commented 4 months ago

User requirements

This will be used in waiting list project to find patients prescribed NSAIDs.

Sensitivity versus specificity

Any PO (tablets, capsules, liquids, granules) / PR (suppositories) NSAIDs

Relevant definitions or links to important reference sources

https://bnf.nice.org.uk/treatment-summaries/non-steroidal-anti-inflammatory-drugs/

Coding system

dm+d

Existing relevant codelists

https://www.opencodelists.org/codelist/opensafely/nsaids-oral/3fe99055/

This codelist was generated in 2020, this codelist will be an update of this list.

Search terms / synonyms / search strategy

BNF code 1001010 used to search for NSAIDS on OpenCodelists

Inclusion criteria for codes

PO (tablets, capsules, liquids, granules) / PR (suppositories)

Exclusion criteria for codes

Injectables will be excluded

Borderline cases

NSAIDs which have names which suggest they are to be used for period pain - excluded not relevant for waiting list study Ibuprofen 100mg/5ml as for babies/infants - excluded not relevant for waiting list study

Final codelist

No response

speed-vm commented 4 months ago

FYI @alschaffer Updated NSAID codelist https://www.opencodelists.org/codelist/user/speed-vm/nsaids/2bf45524/ @chrisjwood16 this is ready for review when you have time please. What do you think about NSAIDs for period pain, and children's preparations?

alschaffer commented 4 months ago

Thanks! Our cohort only includes adults so excluding children's formulations is fine. Re: NSAIDs for period pain, when I look up Feminax Express the pharmacy websites (eg Boots) say: "Also suitable for relief of rheumatic pain, nerve pain, migraine, dental pain, fever and symptoms of cold and flu." So maybe include? Unless it's unlikely to be prescribed for non-period pain.

chrisjwood16 commented 4 months ago

@speed-vm I'd be tempted to be quite inclusive with this. I doubt much prescribing of the very specific period pain products but we are including other NSAIDs most likely used for dysmenorrhoea e.g. mefenamic acid. I think easier to include all NSAID products. Similar for oral solutions etc - most likely to be used for children but could be for complex patients with swallowing issues etc who would be excluded. The paeds patients will be screened based on study inclusion / exclusion criteria.

speed-vm commented 4 months ago

Excellent, I agree. Have added them all back in for inclusive approach. Codelist below

https://www.opencodelists.org/codelist/user/speed-vm/nsaids/12e4e1ef/#full-list

chrisjwood16 commented 4 months ago

Reviewed and happy to approve. Just to note the description mentions this is an update of previous codelist - the previous codelist only included oral formulations - this also adds suppositories which seems reasonable but may change numbers slightly.

speed-vm commented 4 months ago

Thank you @chrisjwood16 Final codelist here @alschaffer https://www.opencodelists.org/codelist/user/speed-vm/nsaids-dmd/1e0e8710/