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Issue tracker for Open Targets Platform and Open Targets Genetics Portal
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Define AOP data model #1442

Closed d0choa closed 2 years ago

d0choa commented 3 years ago

Validated Adverse Outcome Pathways coming from AOPwiki provide proteins involved in key molecular initiating events (MIEs). As part of the target safety project, we want to create two different datasets from the information described in AOPwiki, one for AOPs and another for MIEs, to be integrated into the target object.

The plan is to explore with the support of @BZdrazil a schema to accommodate the relevant information coming from AOPwiki.

The ongoing schema review can be found here: https://docs.google.com/spreadsheets/d/1OZidpR3kQIp1-FOU49PQQXgvSwL2kbM4GPTmvGqhPUU/edit?usp=sharing

ireneisdoomed commented 3 years ago

A first iteration of these two datasets has been generated and is available here:

Both have been reviewed and although they need minor changes, the proposed schema seems to be compliant with the data.

More details to follow on #1605

d0choa commented 2 years ago

I consider the data model defined. Action is following in #1605