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mixer
Causal Mixture Model for GWAS summary statistics
GNU General Public License v3.0
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Ongoing development of MiXeR
#9
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ofrei
closed
5 years ago
ofrei
commented
5 years ago
breaking change: new LD matrix storage and calculation, now using signed "r" instead of r2
preliminary version of the causal mixture with annotations from Alexey Shadrin
python port of matlab runner for cross-trait MiXeR
cost function via 1D and 2D pdf convolution and cubature integration
port a bunch of code from plink to calculate LD matrix, and convenient LD matrix retrieval
support of fixed effects model: get/set causalbetavec, calc_fixed_effects_delta
bivariate posterior delta calculation via analytical integrals