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rgcgithub / regenie

regenie is a C++ program for whole genome regression modelling of large genome-wide association studies.
https://rgcgithub.github.io/regenie
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regenie for survival analysis? #167

Open Shicheng-Guo opened 3 years ago

Shicheng-Guo commented 3 years ago

Dear Joelle, any plan to support survival analysis with regenie. Shicheng

joellembatchou commented 3 years ago

Yes we have planned this enhancement to Regenie.

wvanrheenen commented 9 months ago

Dear REGENIE team, a time-to-event extension would be really nice indeed. Do you have an expected release date for this already? Thanks for the great work. Wouter

joellembatchou commented 9 months ago

This is in active development and we will announce it on the Github page when it is ready for public release.

Thank you, Joelle

GelatinousGiant commented 9 months ago

Hi @joellembatchou -- hope you're doing well.

I very much appreciate you and your teams ongoing work with REGENIE. Our group uses this model constantly and it is really tremendously useful. I wonder (and I do appreciate how difficult of a question this may be!) if you have any sort of rough timeline as to when a Regenie time to event model may be available? We are undertaking some time to event analysis as well as case/control analysis and doing the latter w REGENIE and it would be great to compare these two approaches with the same software/underlying methods if at all possible

katherinef commented 8 months ago

Are you also planning to support use of gene-based tests for survival analyses? Many thanks, Kath

joellembatchou commented 8 months ago

Hi @GelatinousGiant, we are hoping to have it released sometime next year (we most likely will first have only single variant & burden test available).

Cheers, Joelle