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Write an R language program to study the Mendelian randomization research method of the relationship between hyperuricemia and hypertension #80

Open zl9099 opened 1 year ago

flows-network-integration[bot] commented 1 year ago

Here is a sample R language program to study the Mendelian randomization research method of the relationship between hyperuricemia and hypertension:

# Load required libraries
library(mendelianrandomization)
library(dplyr)
library(ggplot2)

# Load data
hyperuricemia_data <- read.csv("hyperuricemia_data.csv")
hypertension_data <- read.csv("hypertension_data.csv")
genetic_instruments_data <- read.csv("genetic_instruments_data.csv")

# Perform a Mendelian randomization analysis
mr_results <- mr_iv(hyperuricemia_data, hypertension_data, genetic_instruments_data)

# Print the results
print(mr_results)

# Visualize the results
ggplot(mr_results, aes(x = log_or, y = snp)) +
  geom_vline(aes(xintercept = 0), linetype = "dashed", color = "red") +
  geom_errorbarh(aes(xmin = lower_ci, xmax = upper_ci)) +
  geom_point(size = 3) +
  ylab("SNP") +
  xlab("Log Odds Ratio") +
  ggtitle("Mendelian Randomization Analysis of Hyperuricemia and Hypertension")

This code assumes that there are three input files: hyperuricemia_data.csv, hypertension_data.csv, and genetic_instruments_data.csv. The mendelianrandomization library is used to perform the Mendelian randomization analysis, and dplyr and ggplot2 are used for data manipulation and visualization.

The results of the analysis are stored in the mr_results variable and can be printed to the console. Additionally, a visualization of the results is created with ggplot2 and can be customized as needed.