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tanghaibao / goatools

Python library to handle Gene Ontology (GO) terms
BSD 2-Clause "Simplified" License
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Do anyone know the differences between the enriched results and the purifed results after the GOEA analysis of the GOATOOLS? #285

Closed Sotdo closed 6 months ago

Sotdo commented 6 months ago

After I run the GOEA analysis using the GOEnrichmentStudyNS function, the output has a column named enrichment. It has two values: e and p, where e represents enriched results and p represents purified results. Do anyone know the differences between these two?

tanghaibao commented 6 months ago

@Sotdo

They are opposite trend. e represent enrichment, which means there are significantly more count in the target term. p is the direct opposite, means that there are significantly fewer count in the target term.

Sotdo commented 6 months ago

@Sotdo

They are opposite trend. e represent enrichment, which means there are significantly more count in the target term. p is the direct opposite, means that there are significantly fewer count in the target term.

Thansk! That's really helpful!