I've looked into this issue, and the fix is to remove the call to assert_unsigned_int32 from cast when casting from i32 to u32, from u32 to i32, and from i32 to u64; and replace it with a call to a new helper called assert_i32, see the implementation of assert_i64 in emit/int64.rs for how to implement it.
The problem is that the assert_unsigned_int32 helper is intended to assert that the sign bit of a 32-bit value is unset, not to assert that the value is non-negative, which is how we are using it in cast.
All the other uses of assert_unsigned_int32 are correct
As described in https://github.com/0xPolygonMiden/compiler/pull/232#discussion_r1672517515