search

10XGenomics / cellranger

10x Genomics Single Cell Analysis
https://www.10xgenomics.com/support/software/cell-ranger
Other
342 stars 91 forks source link

a piece of information about AGGR #106

Closed tanasa closed 3 years ago

tanasa commented 3 years ago

Dear all,

would you please let me know how precisely the normalization works when combining two scRNA-seq samples with CELLAGGR ? if you could let me know the mathematical formula, or offer an example on two very small matrices, it would be extraordinary.

many thanks,

-- bogdan

evolvedmicrobe commented 3 years ago

Hi Bogdan,

Please see the section on Depth Normalization here: https://support.10xgenomics.com/single-cell-gene-expression/software/pipelines/latest/using/aggregate for a description, if you have any further questions please reach out to support@10xgenomics.com for further insights.

Warm wishes, N

tanasa commented 3 years ago

thank you very much Nigel !