Thank you for developing this nice tool.
I have single-cell RNA sequencing (scRNA-seq) data from tissues created by crossing two distinct mouse strains. I am aware of the single nucleotide variants (SNVs) in the parent genomes. I am interested in determining Allele-Specific Expression (ASE) in all expressed genes within my scRNA-seq dataset. What is the best approach for conducting this analysis? Do you have a pipeline designed for this purpose?
Thank you
Thank you for developing this nice tool. I have single-cell RNA sequencing (scRNA-seq) data from tissues created by crossing two distinct mouse strains. I am aware of the single nucleotide variants (SNVs) in the parent genomes. I am interested in determining Allele-Specific Expression (ASE) in all expressed genes within my scRNA-seq dataset. What is the best approach for conducting this analysis? Do you have a pipeline designed for this purpose? Thank you