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524D / compareMS2

Compare samples by MS2 spectra
MIT License
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Possible intensity scaling issue for two-dataset comparison #53

Open magnuspalmblad opened 8 months ago

magnuspalmblad commented 8 months ago

I noticed that the dot products are much lower when scaling the spectra (i.e. using a value for Scaling far from 1), even when removing low-intensity (noise) peaks. Is this expected? In absence of noise, I would not expect scaling spectra to have such a dramatic effect. Two spectra that are very similar before scaling, should also be very similar after scaling.

magnuspalmblad commented 8 months ago

The behavior reported above was for Scaling <<1. For Scaling > 1, the dot products are higher.