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I have selected two sets of instrumental SNPs from index SNPs of a large GWAS for MR-PRESSO, with numbers of 30 and 40 respectively. Both sets include one same SNP with strongest effect on exposure (b…
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**Is your feature request related to a problem? **
- In real world, things aren't perfect. A system doesn't perform necessarily at 100% efficiency. It should be the same in mars-sim.
**Describe th…
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Continues #12
I think another great speed-up can be achieved by optimizing `transform_data_step` (formerly `extract_adjustment_data`) which generates the data required to fit models in a step of t…
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(going a bit in circles)
- Bernstein polynomial density estimation is a kind of kernel estimation based on histogram data, or grouped probabilities. domain is interval [0,1] #7296
- in fast kde w…
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We're not planning to build the simulator for a while but I wanted to start this feature request so we can keep notes about the simulator.
Some specific feature ideas:
- Test the effect of:
- chang…
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(coming back to t-distribution MLE after robust readings)
motivation: heavy-tailed distribution but not clear outliers
current: TModel, TArma in `miscmodels`, t-based covariance in outlier robus…
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For means, for SDρ, for moderator effects.
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If they only had 14 neurons, can this be considered statistically significant? I may have missed this in class, I went to the bathroom.
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After a couple of months of working with the algorithm (including both modifying these scripts and writing another application that implements it with online variational Bayes), I think I see a proble…
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# Association
- [ ] [A simple, consistent estimator of heritability for genome-wide association studies]( https://www.biorxiv.org/content/biorxiv/early/2017/10/17/204446.full.pdf)
- [x] [Multivari…