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@jeizenga @adamnovak
Some of the reads when running 3 GB .fastq.gz chunks of reads from a whole genome HG002 readset are very slow on `vg mpmap` and can occupy a single thread for hours. Graph refer…
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## Development Options
1. Extend VG / XG with our new Graph Summarization Concepts
2. Summary is stored in our database, XG still used at nucleotide level
3. Import entire XG graph into our databas…
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In GFA1, we are using CIGAR to describe overlaps between two segments. It was my idea initially, and I admit it is not a good one. @thegenemyers [proposed](https://github.com/thegenemyers/GFA-spec/blo…
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CC @thegenemyers, @richarddurbin, @ekg, @rrwick, @sjackman, @jts, @pb-jchin, @skoren, @aphillippy, @MihaiPop, @ggonnella, @pmelsted, @edawson
## The current status of GFA1
There were two general-purp…
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This issue is meant for crowdsourcing knowledge about joining NGS/VCF-derived variant databases, which the GA4GH schemas are oriented towards, and clinical variation databases, which tend to prefer [H…