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The model fit below, using the SAEM method, gives the output further below. The initial guess for resp_add_sd is 0.005 and it jumps at iteration 1 to 0.996, and then stays around 1 the whole rest of …
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Currently all plots displaying random effects in ggPMX are based on conditional mode of EBEs which might be affected by shrinkage. To overcome this Monolix generates conditional distribution which is …
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(Having taken a quick look at the first few hits I'm not sure this is going to provide a lot of actionable material, but it's worth a look ...)
```r
remotes::install_github("DylanDijk/CTVsuggest")…
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Hi Dr. Lavielle,
I trying to modify one of your PK/PD shiny templates for one of my projects using mlxr. I have two questions: 1) are those templates free to use? 2) Is mlxr dependent on monolix? I…
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Hi,
I was trying to see where the vpc package is used? Is it no longer used? If so, it can be dropped as a dependency.
Also, I was wondering if you wouldn't mind making the `vpc` a s3-compatib…
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I just upgraded my MacOS to Catalina and to MonolixSuite2020R1. I kept my install of 2019R2 as well. Running R 4.0.3, mlxR 4.1.3. I have a copy of the standard model "oral1_2cpt_kaClV1QV2.txt" in the …
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Hi Marc,
simulating complex models for 500 and more individuals can result in long computation times. Do you plan to support or is there a way to implement such a simulation to run in parallel on m…
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Potential bug with inter-occasion variability (time-varying covariate) when using OCC argument in v1.2.6. See error in screenshot below.
![image](https://user-images.githubusercontent.com/49687660/17…
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"> project.file res1 "
I'm trying to run the example on the Simulx website userguide, usng both my own Project data and the Theophyllin projréct, and get this error.
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Hi,
this is probably related to my data/model file but I cannot figure out why I cannot use simulx with my model. The mlxtran file is attached.
I have 3 different types of observation in my data…