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Is the definition of transporter narrow enough?
I would tend not to annotate things to transpoter
activity unless they are actually 'transporters' of
some sort, not just if they have been shown to be…
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Hello,
You may recall that a couple of years ago I requested
some changes be made to the transporter ontology in
regard to the ABC transporters. Since then, a
SourceForge ticket was opened which indi…
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I'm anxious to hear everyone's gene reports tonight. With the remaining time, I will talk a bit about protein folding and we will play fold.it. If you get a chance, download it and check it out. htt…
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A new term, 'protein folding/unfolding assay' is needed to annotate PMID:19940245 (Fig 1).
Here, unfolding of a substrate protein is used to demonstrate interactions between subunits
of a chaperone (C…
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We want to allow protein complexes to be the value/filler of enabled_by slots, as well as simple gene products.
Protein complexes can be pre-composed (e.g. in PRO or Intact) or post-composed.
Ticket…
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"cell-type specific apoptotic process" is a 'meta-term' - impossible to define logically: all apoptosis occurs in some specific cell type. I'd favour getting rid of it.
More immediately, this is a…
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new GO term, “chaperonin-mediated protein folding”. It would be a child of GO:0006457“protein folding” and a parent of GO:0007022 “chaperonin-mediated tubulin folding”.
Definition: Partial or complete…
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IPR019538
I'm not sure about this. It seems to be a chaperone involved in "assembly" rather than folding?
Perhaps the description should be changedto reflect this (it doesn't appear to be a regulato…
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Achaperone cofactor -dependent protein refolding has
no relationship to
Bchaperone mediated protein folding requiring cofactor,
even though A is a direct child of protein folding. is this intentional…
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dbxref:BHF
Hi
please could this term be created as neg reg child of GO:0042026 protein refolding
New term: negative regulation of protein folding
for the annotation of Bag5, rat, Q5QJC9 PMID: 1560…