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TDMore should be able to work transparently with a TIME that is Calendar times (R class `POSIXct`).
This should be fully transparent in all model functions. We simply need to define a consistent "w…
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The notes for this pre-release include:
"Support of NONMEM-style datasets directly (except MDV and some other less used data items)"
MDV is an important data item in a NONMEM data set. Why can't…
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If DV is defined in $input like this
$INPUT ID PTNM TIME DV=X EVID....
To identify DV, I used this in xpose:
xpdb =xpdb %>% set_var_types(dv="SLD",iwres = "CIWRES")
When running
xpdb %>% …
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See Issue #243 for discussion.
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When reading the data into xpose I get the following messages:
Looking for nonmem output tables.
Reading: sdtab1, patab1, cotab1, catab1 [$prob no.1]
Looking for nonmem output files
Re…
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I want to use RxODE for simulation where the PK parameters abruptly change with events (specifically, the onset/offset of cardipulmonary bypass). I can call RxODE 3 times: before bypass, during bypass…
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The tests currently don't all succeed on platforms other than Windows. It would be helpful if they ran successfully to very similar results (e.g. with a tolerance
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Read the documentation for the nlmixr DSL https://nlmixrdevelopment.github.io/nlmixr_bookdown/vignettes.html#nlmixr-domain-specific-language
And use this to propose an API for tdmore. I would sugge…
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Hi,
I am a beginner in NONMEM (using PsN) and trying to run VPC through it.
By now, I know to assign a problem no. for estimation and another for simulation in control stream and run vpc in xpose wi…
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For dosing events, could you advise how to code in mrgsolve for dosing that is dependent on weight and age, which varies for every record in the data for each ID? For example for a one-compartment mo…