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One of my parameters is named "ETA(CL)", and this appears to cause the following error:
```
prm_distrib(xpdb=xpdb)
Error in ETA(CL) : could not find function "ETA"
```
The `traceback()` sugge…
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Hi,
To implement an approximated transit compartment absorption model for repeating dosing study design, I would need to capture the time of dosing events (which might vary from simulation/id to si…
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NONMEM has a very nice format to define steady-state dosing.
We should at least support this at the model / prediction level.
This will allow us to find the dose that puts the patient within targe…
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Hi Hadley,
Low priority question but might give you some user feedback.
I wanted to check with you to see if this was a reasonable implementation strategy based on your documentation:
Software I us…
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Hi,
When I run the example from [here,](https://github.com/nlmixrdevelopment/nlmixr/blob/master/vignettes/running_nlmixr.Rmd) the output of fit does not show any OBJF using SAEM estimation method. …
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Hi Kyle,
You have an interesting article about complex dosing here:
https://mrgsolve.github.io/blog/2017-complex-events.html
RxODE has something similar and I was cross-checking and came acro…
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I think crayon should be disabled in non-interactive mode. What do you think? Its an easy enough check to add:
```R
interactive()
```
If you think so, I could add a pull request.
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The lst file generated by NONMEM after a sir run cannot be parsed by PsN causing a crash.
Add below to for example pheno to reproduce:
`$COVARIANCE SIRSAMPLE=2000 SIRNITER=1 SIRCENTER=1 IACCEPT=0.…
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The file `nonmem.txt` is output from a PK/PD program, truncated after a few lines. Original is 10000+
It reads Ok but slowly with `read.table`.
http://www.menne-biomed.de/uni/nonmem.txt
I don't wa…
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Hello!
How to handle zero order absorption using nlmixR? I added a column RATE= -2, because I need to estimate a Tk0
Is it possible with limCmt()?
This model has one-compartment with zero-order ab…