Describe the problem

I ran antsMultivariateTemplateConstruction2.sh and it took 56 hours to create a template using 5 subjects as a test. Creating a population-based template (> 300 subjects) using a large number of subjects is expected to take too long.

Is there an efficient way to reduce the execution time?
Additionally, I have a few questions to ask about setting the parameters in antsMultivariateTemplateConstruction2.sh. 2.1 Is it possible to use only 0 (run serially) for the -c option unless it is a supercomputer or cluster? 2.2 If I set it to 0 in the -e option, can I use it as a 32-bit double? 2.3 Does the maximum number of iterations of the -i option mean that the entire registration process repeats the set number of times? Is there a way to quantitatively test the effectiveness of iterations to determine the optimal number of reps? 2.4 I've read the description of antsMultivariateTemplateConstruction2.sh, but I still don't understand it. Can you explain the -q, -f, and -s options in detail? -q option shows the maximum number of iterations of each pairwise registration, and I saw that it was set from A x B x C (e.g., 100x50x20) to A x B x C x D x E x F x G (e.g., 1000x1000x1000x700x500x200x50). Can you tell me what the element means for each dimension -f and -s as well? 2.5 I tried changing the number in ITK_GLOBAL_DEFAULT_NUMBER_OF_THREADS but it doesn't work properly: 4, 8 and 16 cpu utilization are equally the same with 37-55%. I don't know why.

To Reproduce

System information (please complete the following information)

OS: Ubuntu (Linux)
OS version: 18.04.6 LTS
Type of system: Desktop

ANTs version information

ANTs code version: 2.3.5 dev267
ANTs installation type: Compiled from source

Additional information

`Some of the process steps are shown below. ... The composite transform comprises the following transforms (in order):

Center of mass alignment using fixed image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz and moving image: /media/hwang/Disk1/brain_template_elderly/test//2000008.nii.gz (type = Euler3DTransform)

number of levels = 4 number of levels = 4 number of levels = 4 fixed image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz moving image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template02000008Repaired.nii.gz fixed image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz moving image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template02000008Repaired.nii.gz fixed image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz moving image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template02000008Repaired.nii.gz Dimension = 3 Number of stages = 3 Use Histogram Matching true Winsorize image intensities true Lower quantile = 0.01 Upper quantile = 0.99 Stage 1 State Image metric = Mattes Fixed image = Image (0x55721583d640) RTTI typeinfo: itk::Image<float, 3u> Reference Count: 2 Modified Time: 1729 Debug: Off Object Name: Observers: none Source: (none) Source output name: (none) Release Data: Off Data Released: False Global Release Data: Off PipelineMTime: 0 UpdateMTime: 1512 RealTimeStamp: 0 seconds LargestPossibleRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] BufferedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] RequestedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] Spacing: [0.800003, 0.4688, 0.4688] Origin: [-102.283, 100.377, -103.987] Direction: 1 0 0 0 -1 0 0 0 1

IndexToPointMatrix: 0.800003 0 0 0 -0.4688 0 0 0 0.4688

PointToIndexMatrix: 1.25 0 0 0 -2.13311 0 0 0 2.13311

Inverse Direction: 1 0 0 0 -1 0 0 0 1

PixelContainer: ImportImageContainer (0x557215846180) RTTI typeinfo: itk::ImportImageContainer<unsigned long, float> Reference Count: 1 Modified Time: 1509 Debug: Off Object Name: Observers: none Pointer: 0x7f2c4c203010 Container manages memory: true Size: 63963136 Capacity: 63963136

Moving image = Image (0x557215841d30) RTTI typeinfo: itk::Image<float, 3u> Reference Count: 2 Modified Time: 1730 Debug: Off Object Name: Observers: none Source: (none) Source output name: (none) Release Data: Off Data Released: False Global Release Data: Off PipelineMTime: 0 UpdateMTime: 1727 RealTimeStamp: 0 seconds LargestPossibleRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] BufferedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] RequestedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] Spacing: [0.799995, 0.4688, 0.4688] Origin: [-98.184, 99.7908, -101.645] Direction: 1 0 0 0 -1 0 0 0 1

IndexToPointMatrix: 0.799995 0 0 0 -0.4688 0 0 0 0.4688

PointToIndexMatrix: 1.25001 0 0 0 -2.13311 0 0 0 2.13311

Inverse Direction: 1 0 0 0 -1 0 0 0 1

PixelContainer: ImportImageContainer (0x55721583de70) RTTI typeinfo: itk::ImportImageContainer<unsigned long, float> Reference Count: 1 Modified Time: 1724 Debug: Off Object Name: Observers: none Pointer: 0x7f2c3ce02010 Container manages memory: true Size: 63963136 Capacity: 63963136

Weighting = 1 Sampling strategy = regular Number of bins = 32 Radius = 4 Sampling percentage = 0.25 Transform = Rigid Gradient step = 0.1 Update field sigma (voxel space) = 0 Total field sigma (voxel space) = 0 Update field time sigma = 0 Total field time sigma = 0 Number of time indices = 0 Number of time point samples = 0 Stage 2 State Image metric = Mattes Fixed image = Image (0x5572158561f0) RTTI typeinfo: itk::Image<float, 3u> Reference Count: 2 Modified Time: 2161 Debug: Off Object Name: Observers: none Source: (none) Source output name: (none) Release Data: Off Data Released: False Global Release Data: Off PipelineMTime: 0 UpdateMTime: 1944 RealTimeStamp: 0 seconds LargestPossibleRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] BufferedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] RequestedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] Spacing: [0.800003, 0.4688, 0.4688] Origin: [-102.283, 100.377, -103.987] Direction: 1 0 0 0 -1 0 0 0 1

IndexToPointMatrix: 0.800003 0 0 0 -0.4688 0 0 0 0.4688

PointToIndexMatrix: 1.25 0 0 0 -2.13311 0 0 0 2.13311

Inverse Direction: 1 0 0 0 -1 0 0 0 1

PixelContainer: ImportImageContainer (0x55721583f860) RTTI typeinfo: itk::ImportImageContainer<unsigned long, float> Reference Count: 1 Modified Time: 1941 Debug: Off Object Name: Observers: none Pointer: 0x7f2c2da01010 Container manages memory: true Size: 63963136 Capacity: 63963136

Moving image = Image (0x557215855e40) RTTI typeinfo: itk::Image<float, 3u> Reference Count: 2 Modified Time: 2162 Debug: Off Object Name: Observers: none Source: (none) Source output name: (none) Release Data: Off Data Released: False Global Release Data: Off PipelineMTime: 0 UpdateMTime: 2159 RealTimeStamp: 0 seconds LargestPossibleRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] BufferedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] RequestedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] Spacing: [0.799995, 0.4688, 0.4688] Origin: [-98.184, 99.7908, -101.645] Direction: 1 0 0 0 -1 0 0 0 1

IndexToPointMatrix: 0.799995 0 0 0 -0.4688 0 0 0 0.4688

PointToIndexMatrix: 1.25001 0 0 0 -2.13311 0 0 0 2.13311

Inverse Direction: 1 0 0 0 -1 0 0 0 1

PixelContainer: ImportImageContainer (0x5572158552a0) RTTI typeinfo: itk::ImportImageContainer<unsigned long, float> Reference Count: 1 Modified Time: 2156 Debug: Off Object Name: Observers: none Pointer: 0x7f2c1e600010 Container manages memory: true Size: 63963136 Capacity: 63963136

Weighting = 1 Sampling strategy = regular Number of bins = 32 Radius = 4 Sampling percentage = 0.25 Transform = Affine Gradient step = 0.1 Update field sigma (voxel space) = 0 Total field sigma (voxel space) = 0 Update field time sigma = 0 Total field time sigma = 0 Number of time indices = 0 Number of time point samples = 0 Stage 3 State Image metric = CC Fixed image = Image (0x55721585b1c0) RTTI typeinfo: itk::Image<float, 3u> Reference Count: 2 Modified Time: 2593 Debug: Off Object Name: Observers: none Source: (none) Source output name: (none) Release Data: Off Data Released: False Global Release Data: Off PipelineMTime: 0 UpdateMTime: 2376 RealTimeStamp: 0 seconds LargestPossibleRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] BufferedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] RequestedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] Spacing: [0.800003, 0.4688, 0.4688] Origin: [-102.283, 100.377, -103.987] Direction: 1 0 0 0 -1 0 0 0 1

IndexToPointMatrix: 0.800003 0 0 0 -0.4688 0 0 0 0.4688

PointToIndexMatrix: 1.25 0 0 0 -2.13311 0 0 0 2.13311

Inverse Direction: 1 0 0 0 -1 0 0 0 1

PixelContainer: ImportImageContainer (0x55721585aff0) RTTI typeinfo: itk::ImportImageContainer<unsigned long, float> Reference Count: 1 Modified Time: 2373 Debug: Off Object Name: Observers: none Pointer: 0x7f2c0f1ff010 Container manages memory: true Size: 63963136 Capacity: 63963136

Moving image = Image (0x55721585e0b0) RTTI typeinfo: itk::Image<float, 3u> Reference Count: 2 Modified Time: 2594 Debug: Off Object Name: Observers: none Source: (none) Source output name: (none) Release Data: Off Data Released: False Global Release Data: Off PipelineMTime: 0 UpdateMTime: 2591 RealTimeStamp: 0 seconds LargestPossibleRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] BufferedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] RequestedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] Spacing: [0.799995, 0.4688, 0.4688] Origin: [-98.184, 99.7908, -101.645] Direction: 1 0 0 0 -1 0 0 0 1

IndexToPointMatrix: 0.799995 0 0 0 -0.4688 0 0 0 0.4688

PointToIndexMatrix: 1.25001 0 0 0 -2.13311 0 0 0 2.13311

Inverse Direction: 1 0 0 0 -1 0 0 0 1

PixelContainer: ImportImageContainer (0x557215841310) RTTI typeinfo: itk::ImportImageContainer<unsigned long, float> Reference Count: 1 Modified Time: 2588 Debug: Off Object Name: Observers: none Pointer: 0x7f2bffdfe010 Container manages memory: true Size: 63963136 Capacity: 63963136

Weighting = 1 Sampling strategy = none Number of bins = 32 Radius = 4 Sampling percentage = 1 Transform = SyN Gradient step = 0.1 Update field sigma (voxel space) = 3 Total field sigma (voxel space) = 0 Update field time sigma = 0 Total field time sigma = 0 Number of time indices = 0 Number of time point samples = 0 Registration using 3 total stages.

Stage 0 iterations = 1000x500x250x0 convergence threshold = 1e-06 convergence window size = 10 number of levels = 4 using the Mattes MI metric (number of bins = 32, weight = 1) preprocessing: winsorizing the image intensities preprocessing: histogram matching the images Shrink factors (level 1 out of 4): [4, 6, 6] Shrink factors (level 2 out of 4): [2, 4, 4] Shrink factors (level 3 out of 4): [1, 2, 2] Shrink factors (level 4 out of 4): [1, 1, 1] smoothing sigmas per level: [4, 2, 1, 0] regular sampling (percentage = 0.25)

Running Euler3DTransform registration

DIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 2DIAGNOSTIC, 1, -7.922592759132e-01, inf, 9.8756e-01, 9.8756e-01, 2DIAGNOSTIC, 2, -7.954074740410e-01, inf, 1.0180e+00, 3.0399e-02, 2DIAGNOSTIC, 3, -8.001347184181e-01, inf, 1.0484e+00, 3.0409e-02, 2DIAGNOSTIC, 4, -8.063756227493e-01, inf, 1.0785e+00, 3.0088e-02, 2DIAGNOSTIC, 5, -8.138854503632e-01, inf, 1.1091e+00, 3.0658e-02, 2DIAGNOSTIC, 6, -8.217271566391e-01, inf, 1.1405e+00, 3.1344e-02, 2DIAGNOSTIC, 7, -8.274927735329e-01, inf, 1.1705e+00, 3.0056e-02, 2DIAGNOSTIC, 8, -8.297904729843e-01, inf, 1.2009e+00, 3.0415e-02, 2DIAGNOSTIC, 9, -8.321392536163e-01, inf, 1.2319e+00, 3.1019e-02, 2DIAGNOSTIC, 10, -8.349481225014e-01, 3.724043024704e-03, 1.2850e+00, 5.3079e-02, 2DIAGNOSTIC, 11, -8.352736234665e-01, 3.061636816710e-03, 1.3161e+00, 3.1068e-02, 2DIAGNOSTIC, 12, -8.354550004005e-01, 2.334087155759e-03, 1.3467e+00, 3.0602e-02, 2DIAGNOSTIC, 13, -8.357959389687e-01, 1.645860495046e-03, 1.3769e+00, 3.0219e-02, 2DIAGNOSTIC, 14, -8.364754915237e-01, 1.077489345334e-03, 1.4075e+00, 3.0616e-02, 2DIAGNOSTIC, 15, -8.371620178223e-01, 6.726863794029e-04, 1.4656e+00, 5.8093e-02, 2DIAGNOSTIC, 16, -8.371725082397e-01, 4.247218312230e-04, 1.4968e+00, 3.1161e-02, 2DIAGNOSTIC, 17, -8.371707797050e-01, 2.848982985597e-04, 1.5287e+00, 3.1876e-02, 2DIAGNOSTIC, 18, -8.372095823288e-01, 1.789594825823e-04, 1.5598e+00, 3.1186e-02, 2DIAGNOSTIC, 19, -8.372856974602e-01, 1.102401802200e-04, 1.5910e+00, 3.1116e-02, 2DIAGNOSTIC, 20, -8.373540639877e-01, 8.760480704950e-05, 1.6214e+00, 3.0429e-02, 2DIAGNOSTIC, 21, -8.375194072723e-01, 6.729573942721e-05, 1.6889e+00, 6.7516e-02, 2DIAGNOSTIC, 22, -8.375185728073e-01, 4.564604751067e-05, 1.7289e+00, 4.0020e-02, 2DIAGNOSTIC, 23, -8.375174999237e-01, 2.671311449376e-05, 1.7659e+00, 3.6993e-02, 2DIAGNOSTIC, 24, -8.375176191330e-01, 1.646038435865e-05, 1.8056e+00, 3.9643e-02, 2DIAGNOSTIC, 25, -8.375161290169e-01, 1.499526479165e-05, 1.8407e+00, 3.5096e-02, 2DIAGNOSTIC, 26, -8.375141620636e-01, 1.245110797754e-05, 1.8947e+00, 5.4042e-02, 2DIAGNOSTIC, 27, -8.375145196915e-01, 9.028548447532e-06, 1.9306e+00, 3.5863e-02, 2DIAGNOSTIC, 28, -8.375142812729e-01, 5.601753855444e-06, 1.9670e+00, 3.6451e-02, 2DIAGNOSTIC, 29, -8.375119566917e-01, 2.864798716473e-06, 2.0023e+00, 3.5315e-02, DIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 2DIAGNOSTIC, 1, -7.429614067078e-01, inf, 3.2385e+00, 1.2362e+00, 2DIAGNOSTIC, 2, -7.434014081955e-01, inf, 3.3649e+00, 1.2641e-01, 2DIAGNOSTIC, 3, -7.437059879303e-01, inf, 3.4939e+00, 1.2898e-01, 2DIAGNOSTIC, 4, -7.438838481903e-01, inf, 3.6203e+00, 1.2643e-01, 2DIAGNOSTIC, 5, -7.441722750664e-01, inf, 3.8962e+00, 2.7585e-01, 2DIAGNOSTIC, 6, -7.441775798798e-01, inf, 4.0824e+00, 1.8627e-01, 2DIAGNOSTIC, 7, -7.441785931587e-01, inf, 4.2296e+00, 1.4716e-01, 2DIAGNOSTIC, 8, -7.441775202751e-01, inf, 4.3762e+00, 1.4662e-01, 2DIAGNOSTIC, 9, -7.441771030426e-01, inf, 4.5269e+00, 1.5065e-01, 2DIAGNOSTIC, 10, -7.441768050194e-01, 9.344451973448e-05, 4.6534e+00, 1.2650e-01, 2DIAGNOSTIC, 11, -7.441774606705e-01, 5.137321932125e-05, 4.8002e+00, 1.4686e-01, 2DIAGNOSTIC, 12, -7.441757917404e-01, 2.586182199593e-05, 4.9485e+00, 1.4823e-01, 2DIAGNOSTIC, 13, -7.441751360893e-01, 1.106874333345e-05, 5.0792e+00, 1.3069e-01, 2DIAGNOSTIC, 14, -7.441744804382e-01, 2.218880354121e-06, 5.2165e+00, 1.3737e-01, 2DIAGNOSTIC, 15, -7.441740036011e-01, 1.883149707282e-06, 5.3648e+00, 1.4827e-01, 2DIAGNOSTIC, 16, -7.441735863686e-01, 1.726544041958e-06, 5.5112e+00, 1.4643e-01, 2DIAGNOSTIC, 17, -7.441743016243e-01, 1.652329729041e-06, 5.6577e+00, 1.4649e-01, 2DIAGNOSTIC, 18, -7.441738843918e-01, 1.575113856234e-06, 5.7845e+00, 1.2683e-01, 2DIAGNOSTIC, 19, -7.441732287407e-01, 1.502660893493e-06, 5.9321e+00, 1.4755e-01, 2DIAGNOSTIC, 20, -7.441730499268e-01, 1.444085683033e-06, 6.0815e+00, 1.4940e-01, 2DIAGNOSTIC, 21, -7.441728711128e-01, 1.413899326508e-06, 6.2478e+00, 1.6629e-01, 2DIAGNOSTIC, 22, -7.441727519035e-01, 1.364617673971e-06, 6.4340e+00, 1.8618e-01, 2DIAGNOSTIC, 23, -7.441729903221e-01, 1.320509795733e-06, 6.6005e+00, 1.6651e-01, 2DIAGNOSTIC, 24, -7.441727519035e-01, 1.272087956750e-06, 6.7476e+00, 1.4711e-01, 2DIAGNOSTIC, 25, -7.441727519035e-01, 1.225704068020e-06, 6.8946e+00, 1.4705e-01, 2DIAGNOSTIC, 26, -7.441726922989e-01, 1.179835749099e-06, 7.0428e+00, 1.4819e-01, 2DIAGNOSTIC, 27, -7.441725730896e-01, 1.149933382294e-06, 7.1826e+00, 1.3976e-01, 2DIAGNOSTIC, 28, -7.441724538803e-01, 1.117712713494e-06, 7.3274e+00, 1.4484e-01, 2DIAGNOSTIC, 29, -7.441723942757e-01, 1.080109200302e-06, 7.4747e+00, 1.4722e-01, 2DIAGNOSTIC, 30, -7.441723346710e-01, 1.043666770784e-06, 7.6209e+00, 1.4623e-01, 2DIAGNOSTIC, 31, -7.441722750664e-01, 1.008263325275e-06, 7.7688e+00, 1.4789e-01, DIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 2DIAGNOSTIC, 1, -6.862111091614e-01, inf, 1.0689e+01, 2.9205e+00, 2DIAGNOSTIC, 2, -6.862404942513e-01, inf, 1.1518e+01, 8.2892e-01, 2DIAGNOSTIC, 3, -6.862771511078e-01, inf, 1.2326e+01, 8.0820e-01, 2DIAGNOSTIC, 4, -6.863639354706e-01, inf, 1.3135e+01, 8.0890e-01, 2DIAGNOSTIC, 5, -6.864207386971e-01, inf, 1.3934e+01, 7.9831e-01, 2DIAGNOSTIC, 6, -6.865378618240e-01, inf, 1.5481e+01, 1.5473e+00, 2DIAGNOSTIC, 7, -6.865482926369e-01, inf, 1.6639e+01, 1.1581e+00, 2DIAGNOSTIC, 8, -6.865493655205e-01, inf, 1.7569e+01, 9.3004e-01, 2DIAGNOSTIC, 9, -6.865487098694e-01, inf, 1.8500e+01, 9.3070e-01, 2DIAGNOSTIC, 10, -6.865491271019e-01, 4.060360151925e-05, 1.9934e+01, 1.4346e+00, 2DIAGNOSTIC, 11, -6.865494251251e-01, 3.067124271183e-05, 2.1013e+01, 1.0786e+00, 2DIAGNOSTIC, 12, -6.865491867065e-01, 2.091933492920e-05, 2.1821e+01, 8.0823e-01, 2DIAGNOSTIC, 13, -6.865493059158e-01, 1.219194473379e-05, 2.2745e+01, 9.2412e-01, 2DIAGNOSTIC, 14, -6.865495443344e-01, 6.398669938790e-06, 2.3694e+01, 9.4905e-01, 2DIAGNOSTIC, 15, -6.865492463112e-01, 2.471669859005e-06, 2.4653e+01, 9.5887e-01, 2DIAGNOSTIC, 16, -6.865493655205e-01, 2.029717279584e-06, 2.5710e+01, 1.0566e+00, 2DIAGNOSTIC, 17, -6.865489482880e-01, 1.879032538454e-06, 2.6651e+01, 9.4100e-01, 2DIAGNOSTIC, 18, -6.865487694740e-01, 1.765758383954e-06, 2.7810e+01, 1.1590e+00, 2DIAGNOSTIC, 19, -6.865488886833e-01, 1.652575633670e-06, 2.8761e+01, 9.5119e-01, 2DIAGNOSTIC, 20, -6.865488290787e-01, 1.559764086778e-06, 2.9809e+01, 1.0481e+00, 2DIAGNOSTIC, 21, -6.865487098694e-01, 1.482451921220e-06, 3.0854e+01, 1.0450e+00, 2DIAGNOSTIC, 22, -6.865487098694e-01, 1.410832737747e-06, 3.1779e+01, 9.2436e-01, 2DIAGNOSTIC, 23, -6.865487098694e-01, 1.350758452645e-06, 3.2719e+01, 9.4004e-01, 2DIAGNOSTIC, 24, -6.865486502647e-01, 1.301813654209e-06, 3.3660e+01, 9.4129e-01, 2DIAGNOSTIC, 25, -6.865486502647e-01, 1.253931600331e-06, 3.4478e+01, 8.1856e-01, 2DIAGNOSTIC, 26, -6.865486502647e-01, 1.213587779603e-06, 3.5409e+01, 9.3076e-01, 2DIAGNOSTIC, 27, -6.865485906601e-01, 1.169936695078e-06, 3.6336e+01, 9.2707e-01, 2DIAGNOSTIC, 28, -6.865485906601e-01, 1.127480118157e-06, 3.7279e+01, 9.4293e-01, 2DIAGNOSTIC, 29, -6.865485906601e-01, 1.090479486265e-06, 3.8208e+01, 9.2914e-01, 2DIAGNOSTIC, 30, -6.865485310555e-01, 1.054950530488e-06, 3.9145e+01, 9.3620e-01, 2DIAGNOSTIC, 31, -6.865485310555e-01, 1.020649960992e-06, 4.0181e+01, 1.0364e+00, DIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 2DIAGNOSTIC, 1, -6.155595183372e-01, inf, 4.7351e+01, 7.1702e+00, Elapsed time (stage 0): 5.1138e+01

Stage 1 iterations = 1000x500x250x0 convergence threshold = 1.0000e-06 convergence window size = 10 number of levels = 4 using the Mattes MI metric (number of bins = 32, weight = 1.0000e+00) preprocessing: winsorizing the image intensities preprocessing: histogram matching the images Shrink factors (level 1 out of 4): [4, 6, 6] Shrink factors (level 2 out of 4): [2, 4, 4] Shrink factors (level 3 out of 4): [1, 2, 2] Shrink factors (level 4 out of 4): [1, 1, 1] smoothing sigmas per level: [4, 2, 1, 0] regular sampling (percentage = 2.5000e-01)

Running AffineTransform registration

DIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 2DIAGNOSTIC, 1, -8.382912874222e-01, inf, 9.9535e-01, 9.9535e-01, 2DIAGNOSTIC, 2, -8.423526883125e-01, inf, 1.0286e+00, 3.3299e-02, 2DIAGNOSTIC, 3, -8.490978479385e-01, inf, 1.0618e+00, 3.3154e-02, 2DIAGNOSTIC, 4, -8.610221743584e-01, inf, 1.0945e+00, 3.2661e-02, 2DIAGNOSTIC, 5, -8.818543553352e-01, inf, 1.1280e+00, 3.3513e-02, 2DIAGNOSTIC, 6, -9.219324588776e-01, inf, 1.1607e+00, 3.2747e-02, 2DIAGNOSTIC, 7, -9.622811079025e-01, inf, 1.2116e+00, 5.0918e-02, 2DIAGNOSTIC, 8, -9.732642769814e-01, inf, 1.2718e+00, 6.0203e-02, 2DIAGNOSTIC, 9, -9.736542701721e-01, inf, 1.3007e+00, 2.8843e-02, 2DIAGNOSTIC, 10, -9.752659201622e-01, 1.229799538851e-02, 1.3313e+00, 3.0649e-02, 2DIAGNOSTIC, 11, -9.776749610901e-01, 1.057149190456e-02, 1.3619e+00, 3.0606e-02, 2DIAGNOSTIC, 12, -9.805310964584e-01, 8.368668146431e-03, 1.3917e+00, 2.9719e-02, 2DIAGNOSTIC, 13, -9.830995798111e-01, 5.997422151268e-03, 1.4211e+00, 2.9423e-02, 2DIAGNOSTIC, 14, -9.843904972076e-01, 3.741851542145e-03, 1.4514e+00, 3.0344e-02, 2DIAGNOSTIC, 15, -9.849218130112e-01, 1.887876307592e-03, 1.4845e+00, 3.3037e-02, 2DIAGNOSTIC, 16, -9.856384992599e-01, 8.600784931332e-04, 1.5177e+00, 3.3213e-02, 2DIAGNOSTIC, 17, -9.863296151161e-01, 6.051082746126e-04, 1.5557e+00, 3.8010e-02, 2DIAGNOSTIC, 18, -9.867457747459e-01, 5.151694640517e-04, 1.5976e+00, 4.1951e-02, 2DIAGNOSTIC, 19, -9.869723320007e-01, 3.975089639425e-04, 1.6345e+00, 3.6879e-02, 2DIAGNOSTIC, 20, -9.871451854706e-01, 2.822387032211e-04, 1.6716e+00, 3.7129e-02, 2DIAGNOSTIC, 21, -9.876413345337e-01, 1.931816805154e-04, 1.7086e+00, 3.6981e-02, 2DIAGNOSTIC, 22, -9.886107444763e-01, 1.457034377381e-04, 1.7784e+00, 6.9751e-02, 2DIAGNOSTIC, 23, -9.886070489883e-01, 1.217230455950e-04, 1.8126e+00, 3.4218e-02, 2DIAGNOSTIC, 24, -9.886169433594e-01, 1.049490674632e-04, 1.8508e+00, 3.8198e-02, 2DIAGNOSTIC, 25, -9.886283874512e-01, 8.636966958875e-05, 1.8977e+00, 4.6905e-02, 2DIAGNOSTIC, 26, -9.886293411255e-01, 6.921158637851e-05, 1.9344e+00, 3.6717e-02, 2DIAGNOSTIC, 27, -9.886285662651e-01, 5.429946395452e-05, 1.9707e+00, 3.6257e-02, 2DIAGNOSTIC, 28, -9.886263608932e-01, 3.987322634202e-05, 2.0080e+00, 3.7320e-02, 2DIAGNOSTIC, 29, -9.886255264282e-01, 2.529810444685e-05, 2.0453e+00, 3.7260e-02, 2DIAGNOSTIC, 30, -9.886273741722e-01, 1.113597136282e-05, 2.0826e+00, 3.7306e-02, 2DIAGNOSTIC, 31, -9.886251688004e-01, 1.409624360349e-06, 2.1202e+00, 3.7612e-02, 2DIAGNOSTIC, 32, -9.886242747307e-01, 1.220534841195e-06, 2.1527e+00, 3.2532e-02, 2DIAGNOSTIC, 33, -9.886295199394e-01, 1.037695483319e-06, 2.1903e+00, 3.7593e-02, DIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 2DIAGNOSTIC, 1, -8.782528042793e-01, inf, 3.4135e+00, 1.2232e+00, 2DIAGNOSTIC, 2, -8.795135021210e-01, inf, 3.5478e+00, 1.3427e-01, 2DIAGNOSTIC, 3, -8.799905180931e-01, inf, 3.7418e+00, 1.9403e-01, 2DIAGNOSTIC, 4, -8.800041079521e-01, inf, 3.9186e+00, 1.7684e-01, 2DIAGNOSTIC, 5, -8.800042271614e-01, inf, 4.1501e+00, 2.3145e-01, 2DIAGNOSTIC, 6, -8.800055980682e-01, inf, 4.3798e+00, 2.2971e-01, 2DIAGNOSTIC, 7, -8.800061345100e-01, inf, 4.5348e+00, 1.5497e-01, 2DIAGNOSTIC, 8, -8.800058960915e-01, inf, 4.6755e+00, 1.4076e-01, 2DIAGNOSTIC, 9, -8.800060153008e-01, inf, 4.8209e+00, 1.4543e-01, 2DIAGNOSTIC, 10, -8.800059556961e-01, 7.410159014398e-05, 4.9753e+00, 1.5440e-01, 2DIAGNOSTIC, 11, -8.800036311150e-01, 1.774707016011e-05, 5.1728e+00, 1.9743e-01, 2DIAGNOSTIC, 12, -8.800036907196e-01, 3.031643700524e-06, 5.3449e+00, 1.7208e-01, 2DIAGNOSTIC, 13, -8.800036311150e-01, 2.387998847553e-06, 5.4975e+00, 1.5267e-01, 2DIAGNOSTIC, 14, -8.800036907196e-01, 2.156316668334e-06, 5.6504e+00, 1.5291e-01, 2DIAGNOSTIC, 15, -8.800037503242e-01, 1.969370941879e-06, 5.7874e+00, 1.3695e-01, 2DIAGNOSTIC, 16, -8.800009489059e-01, 1.791249133021e-06, 5.9734e+00, 1.8602e-01, 2DIAGNOSTIC, 17, -8.800008893013e-01, 1.663143393671e-06, 6.1468e+00, 1.7337e-01, 2DIAGNOSTIC, 18, -8.800010085106e-01, 1.565075649523e-06, 6.3051e+00, 1.5836e-01, 2DIAGNOSTIC, 19, -8.800008893013e-01, 1.494792400081e-06, 6.4387e+00, 1.3353e-01, 2DIAGNOSTIC, 20, -8.800008296967e-01, 1.447591330361e-06, 6.5918e+00, 1.5318e-01, 2DIAGNOSTIC, 21, -8.800009489059e-01, 1.385034238410e-06, 6.7454e+00, 1.5357e-01, 2DIAGNOSTIC, 22, -8.800008893013e-01, 1.340417497886e-06, 6.8823e+00, 1.3685e-01, 2DIAGNOSTIC, 23, -8.800009489059e-01, 1.308921923737e-06, 7.0328e+00, 1.5052e-01, 2DIAGNOSTIC, 24, -8.800006508827e-01, 1.283331471313e-06, 7.1874e+00, 1.5460e-01, 2DIAGNOSTIC, 25, -8.800007700920e-01, 1.267236939384e-06, 7.3412e+00, 1.5378e-01, 2DIAGNOSTIC, 26, -8.800008296967e-01, 1.218736997544e-06, 7.4932e+00, 1.5207e-01, 2DIAGNOSTIC, 27, -8.800007700920e-01, 1.172732709165e-06, 7.6482e+00, 1.5495e-01, 2DIAGNOSTIC, 28, -8.800007700920e-01, 1.132018496719e-06, 7.8015e+00, 1.5336e-01, 2DIAGNOSTIC, 29, -8.800008296967e-01, 1.093916125683e-06, 7.9548e+00, 1.5331e-01, 2DIAGNOSTIC, 30, -8.800008893013e-01, 1.058569637280e-06, 8.1080e+00, 1.5321e-01, 2DIAGNOSTIC, 31, -8.800007104874e-01, 1.025009510158e-06, 8.2627e+00, 1.5461e-01, DIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 2DIAGNOSTIC, 1, -8.043214082718e-01, inf, 1.1189e+01, 2.9263e+00, 2DIAGNOSTIC, 2, -8.048267364502e-01, inf, 1.2721e+01, 1.5325e+00, 2DIAGNOSTIC, 3, -8.048284649849e-01, inf, 1.4251e+01, 1.5295e+00, 2DIAGNOSTIC, 4, -8.048281073570e-01, inf, 1.5318e+01, 1.0669e+00, 2DIAGNOSTIC, 5, -8.048271536827e-01, inf, 1.6751e+01, 1.4333e+00, 2DIAGNOSTIC, 6, -8.048271536827e-01, inf, 1.7806e+01, 1.0551e+00, 2DIAGNOSTIC, 7, -8.048276901245e-01, inf, 1.8858e+01, 1.0516e+00, 2DIAGNOSTIC, 8, -8.048275709152e-01, inf, 1.9914e+01, 1.0565e+00, 2DIAGNOSTIC, 9, -8.048267960548e-01, inf, 2.1121e+01, 1.2064e+00, 2DIAGNOSTIC, 10, -8.048266172409e-01, 2.099566154357e-05, 2.2202e+01, 1.0809e+00, 2DIAGNOSTIC, 11, -8.048269152641e-01, 2.825430556186e-06, 2.3256e+01, 1.0539e+00, 2DIAGNOSTIC, 12, -8.048264980316e-01, 2.545855977587e-06, 2.4312e+01, 1.0566e+00, 2DIAGNOSTIC, 13, -8.048263192177e-01, 2.361271981499e-06, 2.5489e+01, 1.1764e+00, 2DIAGNOSTIC, 14, -8.048262000084e-01, 2.200212975367e-06, 2.6565e+01, 1.0765e+00, 2DIAGNOSTIC, 15, -8.048260807991e-01, 2.042035248451e-06, 2.7633e+01, 1.0675e+00, 2DIAGNOSTIC, 16, -8.048262596130e-01, 1.914062522701e-06, 2.8693e+01, 1.0607e+00, 2DIAGNOSTIC, 17, -8.048262000084e-01, 1.817653128455e-06, 2.9733e+01, 1.0396e+00, 2DIAGNOSTIC, 18, -8.048262000084e-01, 1.735193336572e-06, 3.0809e+01, 1.0756e+00, 2DIAGNOSTIC, 19, -8.048260807991e-01, 1.647904014135e-06, 3.1853e+01, 1.0450e+00, 2DIAGNOSTIC, 20, -8.048260807991e-01, 1.568419065734e-06, 3.2901e+01, 1.0471e+00, 2DIAGNOSTIC, 21, -8.048253655434e-01, 1.491618377258e-06, 3.3950e+01, 1.0490e+00, 2DIAGNOSTIC, 22, -8.048251867294e-01, 1.414727421434e-06, 3.5052e+01, 1.1028e+00, 2DIAGNOSTIC, 23, -8.048252463341e-01, 1.345644932371e-06, 3.6106e+01, 1.0541e+00, 2DIAGNOSTIC, 24, -8.048252463341e-01, 1.283943220187e-06, 3.7154e+01, 1.0478e+00, 2DIAGNOSTIC, 25, -8.048249483109e-01, 1.225112214343e-06, 3.8209e+01, 1.0552e+00, 2DIAGNOSTIC, 26, -8.048249483109e-01, 1.177984245260e-06, 3.9164e+01, 9.5488e-01, 2DIAGNOSTIC, 27, -8.048248887062e-01, 1.137080175795e-06, 4.0225e+01, 1.0610e+00, 2DIAGNOSTIC, 28, -8.048250079155e-01, 1.104328930523e-06, 4.1306e+01, 1.0803e+00, 2DIAGNOSTIC, 29, -8.048248887062e-01, 1.073753196579e-06, 4.2402e+01, 1.0958e+00, 2DIAGNOSTIC, 30, -8.048247098923e-01, 1.045633553076e-06, 4.3536e+01, 1.1343e+00, 2DIAGNOSTIC, 31, -8.048248291016e-01, 1.014077270156e-06, 4.4661e+01, 1.1256e+00, DIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 2DIAGNOSTIC, 1, -7.111817598343e-01, inf, 5.2227e+01, 7.5657e+00, Elapsed time (stage 1): 5.5996e+01

Stage 2 iterations = 100x100x70x20 convergence threshold = 1.0000e-09 convergence window size = 10 number of levels = 4 using the CC metric (radius = 4, weight = 1.0000e+00) preprocessing: winsorizing the image intensities preprocessing: histogram matching the images Shrink factors (level 1 out of 4): [4, 6, 6] Shrink factors (level 2 out of 4): [2, 4, 4] Shrink factors (level 3 out of 4): [1, 2, 2] Shrink factors (level 4 out of 4): [1, 1, 1] smoothing sigmas per level: [3, 2, 1, 0] Using default NONE metricSamplingStrategy

Running SyN registration (varianceForUpdateField = 3.0000e+00, varianceForTotalField = 0.0000e+00)

XXDIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 1DIAGNOSTIC, 1, -8.694797754288e-01, inf, 2.4278e+00, 2.4278e+00, 1DIAGNOSTIC, 2, -8.772150874138e-01, inf, 4.0333e+00, 1.6055e+00, 1DIAGNOSTIC, 3, -8.857214450836e-01, inf, 5.6628e+00, 1.6294e+00, 1DIAGNOSTIC, 4, -8.928368091583e-01, inf, 7.1993e+00, 1.5365e+00, 1DIAGNOSTIC, 5, -8.989784717560e-01, inf, 8.8232e+00, 1.6240e+00, 1DIAGNOSTIC, 6, -9.043725728989e-01, inf, 1.0417e+01, 1.5938e+00, 1DIAGNOSTIC, 7, -9.083673357964e-01, inf, 1.2028e+01, 1.6109e+00, 1DIAGNOSTIC, 8, -9.120550155640e-01, inf, 1.3671e+01, 1.6435e+00, 1DIAGNOSTIC, 9, -9.154336452484e-01, inf, 1.5295e+01, 1.6236e+00, 1DIAGNOSTIC, 10, -9.186135530472e-01, 3.456590697169e-03, 1.6959e+01, 1.6639e+00, 1DIAGNOSTIC, 11, -9.216923713684e-01, 2.753026550636e-03, 1.8603e+01, 1.6445e+00, 1DIAGNOSTIC, 12, -9.246071577072e-01, 2.198094502091e-03, 2.0144e+01, 1.5401e+00, 1DIAGNOSTIC, 13, -9.273712635040e-01, 1.801653881557e-03, 2.1753e+01, 1.6096e+00, 1DIAGNOSTIC, 14, -9.298100471497e-01, 1.511104637757e-03, 2.3384e+01, 1.6311e+00, 1DIAGNOSTIC, 15, -9.319955110550e-01, 1.293968525715e-03, 2.5021e+01, 1.6363e+00, 1DIAGNOSTIC, 16, -9.339622855186e-01, 1.128485426307e-03, 2.6633e+01, 1.6124e+00, 1DIAGNOSTIC, 17, -9.355418682098e-01, 9.802567074075e-04, 2.8276e+01, 1.6430e+00, 1DIAGNOSTIC, 18, -9.368922710419e-01, 8.447284926660e-04, 2.9919e+01, 1.6434e+00, 1DIAGNOSTIC, 19, -9.380041360855e-01, 7.184069836512e-04, 3.1492e+01, 1.5724e+00, 1DIAGNOSTIC, 20, -9.389182329178e-01, 6.012763478793e-04, 3.3094e+01, 1.6018e+00, 1DIAGNOSTIC, 21, -9.396685957909e-01, 4.956094780937e-04, 3.4658e+01, 1.5644e+00, 1DIAGNOSTIC, 22, -9.403849840164e-01, 4.041861102451e-04, 3.6238e+01, 1.5800e+00, 1DIAGNOSTIC, 23, -9.409135580063e-01, 3.270110755693e-04, 3.7808e+01, 1.5696e+00, 1DIAGNOSTIC, 24, -9.414362907410e-01, 2.636227000039e-04, 3.9395e+01, 1.5870e+00, 1DIAGNOSTIC, 25, -9.418870210648e-01, 2.129530621460e-04, 4.0974e+01, 1.5793e+00, 1DIAGNOSTIC, 26, -9.422878623009e-01, 1.741477317410e-04, 4.2592e+01, 1.6183e+00, 1DIAGNOSTIC, 27, -9.426569342613e-01, 1.439734332962e-04, 4.4170e+01, 1.5778e+00, 1DIAGNOSTIC, 28, -9.430227279663e-01, 1.211981725646e-04, 4.5800e+01, 1.6305e+00, 1DIAGNOSTIC, 29, -9.433961510658e-01, 1.042768053594e-04, 4.7424e+01, 1.6234e+00, 1DIAGNOSTIC, 30, -9.437922835350e-01, 9.203209629050e-05, 4.8960e+01, 1.5365e+00, 1DIAGNOSTIC, 31, -9.442227482796e-01, 8.353443263331e-05, 5.0526e+01, 1.5655e+00, 1DIAGNOSTIC, 32, -9.446840286255e-01, 7.895418821136e-05, 5.2152e+01, 1.6264e+00, 1DIAGNOSTIC, 33, -9.451792240143e-01, 7.666456804145e-05, 5.3702e+01, 1.5497e+00, 1DIAGNOSTIC, 34, -9.457093477249e-01, 7.671374623897e-05, 5.5274e+01, 1.5718e+00, 1DIAGNOSTIC, 35, -9.461958408356e-01, 7.766449562041e-05, 5.6883e+01, 1.6090e+00, 1DIAGNOSTIC, 36, -9.467729330063e-01, 7.950418512337e-05, 5.8432e+01, 1.5490e+00, 1DIAGNOSTIC, 37, -9.472941160202e-01, 8.102643914754e-05, 6.0069e+01, 1.6376e+00, 1DIAGNOSTIC, 38, -9.476791024208e-01, 8.079450344667e-05, 6.1698e+01, 1.6285e+00, 1DIAGNOSTIC, 39, -9.480301141739e-01, 7.858892058721e-05, 6.3310e+01, 1.6124e+00, 1DIAGNOSTIC, 40, -9.483132362366e-01, 7.421381451422e-05, 6.4905e+01, 1.5944e+00, 1DIAGNOSTIC, 41, -9.485806226730e-01, 6.818294059485e-05, 6.6513e+01, 1.6082e+00, 1DIAGNOSTIC, 42, -9.488016366959e-01, 6.089557791711e-05, 6.8114e+01, 1.6014e+00, 1DIAGNOSTIC, 43, -9.490117430687e-01, 5.316098759067e-05, 6.9763e+01, 1.6484e+00, 1DIAGNOSTIC, 44, -9.491838216782e-01, 4.560577872326e-05, 7.1384e+01, 1.6209e+00, 1DIAGNOSTIC, 45, -9.493501186371e-01, 3.846067193081e-05, 7.2983e+01, 1.5991e+00, 1DIAGNOSTIC, 46, -9.494857192039e-01, 3.267781721661e-05, 7.4565e+01, 1.5819e+00, 1DIAGNOSTIC, 47, -9.496273398399e-01, 2.833957114490e-05, 7.6206e+01, 1.6417e+00, 1DIAGNOSTIC, 48, -9.497348070145e-01, 2.461897565809e-05, 7.7814e+01, 1.6074e+00, 1DIAGNOSTIC, 49, -9.498543739319e-01, 2.165442492696e-05, 7.9409e+01, 1.5948e+00, 1DIAGNOSTIC, 50, -9.499434828758e-01, 1.903250813484e-05, 8.1041e+01, 1.6328e+00, 1DIAGNOSTIC, 51, -9.500396847725e-01, 1.689954660833e-05, 8.2638e+01, 1.5971e+00, 1DIAGNOSTIC, 52, -9.501159787178e-01, 1.500451435277e-05, 8.4253e+01, 1.6145e+00, 1DIAGNOSTIC, 53, -9.502013325691e-01, 1.348003024759e-05, 8.5866e+01, 1.6133e+00, 1DIAGNOSTIC, 54, -9.502604007721e-01, 1.205924490932e-05, 8.7511e+01, 1.6443e+00, 1DIAGNOSTIC, 55, -9.503338932991e-01, 1.090381010727e-05, 8.9084e+01, 1.5730e+00, 1DIAGNOSTIC, 56, -9.503864049911e-01, 9.803596185520e-06, 9.0687e+01, 1.6039e+00, 1DIAGNOSTIC, 57, -9.504463672638e-01, 8.920793334255e-06, 9.2284e+01, 1.5969e+00, 1DIAGNOSTIC, 58, -9.504906535149e-01, 8.046907169046e-06, 9.3923e+01, 1.6384e+00, 1DIAGNOSTIC, 59, -9.505461454391e-01, 7.376494522759e-06, 9.5558e+01, 1.6354e+00, 1DIAGNOSTIC, 60, -9.505810141563e-01, 6.688197117910e-06, 9.7186e+01, 1.6280e+00, 1DIAGNOSTIC, 61, -9.506355524063e-01, 6.175172075018e-06, 9.8779e+01, 1.5931e+00, 1DIAGNOSTIC, 62, -9.506629705429e-01, 5.632680768031e-06, 1.0035e+02, 1.5726e+00, 1DIAGNOSTIC, 63, -9.507111310959e-01, 5.255112682789e-06, 1.0195e+02, 1.6006e+00, 1DIAGNOSTIC, 64, -9.507389664650e-01, 4.835737854592e-06, 1.0358e+02, 1.6289e+00, 1DIAGNOSTIC, 65, -9.507762193680e-01, 4.525001259026e-06, 1.0517e+02, 1.5889e+00, 1DIAGNOSTIC, 66, -9.507976174355e-01, 4.168881787336e-06, 1.0678e+02, 1.6051e+00, 1DIAGNOSTIC, 67, -9.508365392685e-01, 3.913573436876e-06, 1.0839e+02, 1.6110e+00, 1DIAGNOSTIC, 68, -9.508595466614e-01, 3.628070999184e-06, 1.0999e+02, 1.6076e+00, 1DIAGNOSTIC, 69, -9.508817195892e-01, 3.385624040675e-06, 1.1164e+02, 1.6449e+00, 1DIAGNOSTIC, 70, -9.509122967720e-01, 3.147750931021e-06, 1.1322e+02, 1.5822e+00, 1DIAGNOSTIC, 71, -9.509266614914e-01, 2.948718929474e-06, 1.1482e+02, 1.5960e+00, 1DIAGNOSTIC, 72, -9.509582519531e-01, 2.758836899375e-06, 1.1644e+02, 1.6256e+00, 1DIAGNOSTIC, 73, -9.509677886963e-01, 2.586991286080e-06, 1.1801e+02, 1.5693e+00, 1DIAGNOSTIC, 74, -9.509961605072e-01, 2.441032620482e-06, 1.1966e+02, 1.6434e+00, 1DIAGNOSTIC, 75, -9.510066509247e-01, 2.295653757756e-06, 1.2121e+02, 1.5565e+00, 1DIAGNOSTIC, 76, -9.510321617126e-01, 2.157750486731e-06, 1.2279e+02, 1.5802e+00, 1DIAGNOSTIC, 77, -9.510379433632e-01, 2.029119059443e-06, 1.2441e+02, 1.6143e+00, 1DIAGNOSTIC, 78, -9.510645270348e-01, 1.940161837410e-06, 1.2600e+02, 1.5934e+00, 1DIAGNOSTIC, 79, -9.510679244995e-01, 1.799975620997e-06, 1.2755e+02, 1.5550e+00, 1DIAGNOSTIC, 80, -9.510918259621e-01, 1.734973352541e-06, 1.2916e+02, 1.6030e+00, 1DIAGNOSTIC, 81, -9.510961771011e-01, 1.608877255421e-06, 1.3075e+02, 1.5931e+00, 1DIAGNOSTIC, 82, -9.511178135872e-01, 1.565647721691e-06, 1.3232e+02, 1.5730e+00, 1DIAGNOSTIC, 83, -9.511206150055e-01, 1.451644379813e-06, 1.3399e+02, 1.6641e+00, 1DIAGNOSTIC, 84, -9.511404037476e-01, 1.411187326994e-06, 1.3559e+02, 1.5978e+00, 1DIAGNOSTIC, 85, -9.511435031891e-01, 1.317631927122e-06, 1.3717e+02, 1.5827e+00, 1DIAGNOSTIC, 86, -9.511573314667e-01, 1.274237888538e-06, 1.3880e+02, 1.6328e+00, 1DIAGNOSTIC, 87, -9.511592388153e-01, 1.168874973700e-06, 1.4038e+02, 1.5805e+00, 1DIAGNOSTIC, 88, -9.511737823486e-01, 1.130559894591e-06, 1.4193e+02, 1.5451e+00, 1DIAGNOSTIC, 89, -9.511746168137e-01, 1.030750809150e-06, 1.4355e+02, 1.6237e+00, 1DIAGNOSTIC, 90, -9.511868953705e-01, 9.904339322020e-07, 1.4512e+02, 1.5717e+00, 1DIAGNOSTIC, 91, -9.511835575104e-01, 8.910627684600e-07, 1.4671e+02, 1.5844e+00, 1DIAGNOSTIC, 92, -9.511952400208e-01, 8.522432040081e-07, 1.4833e+02, 1.6243e+00, 1DIAGNOSTIC, 93, -9.511943459511e-01, 7.694164310124e-07, 1.4993e+02, 1.6003e+00, 1DIAGNOSTIC, 94, -9.512087702751e-01, 7.575430913676e-07, 1.5151e+02, 1.5747e+00, 1DIAGNOSTIC, 95, -9.512047171593e-01, 7.008618467808e-07, 1.5311e+02, 1.6087e+00, 1DIAGNOSTIC, 96, -9.512176513672e-01, 6.955717708479e-07, 1.5471e+02, 1.5996e+00, 1DIAGNOSTIC, 97, -9.512137770653e-01, 6.475596023847e-07, 1.5628e+02, 1.5693e+00, 1DIAGNOSTIC, 98, -9.512249231339e-01, 6.495659476968e-07, 1.5791e+02, 1.6280e+00, 1DIAGNOSTIC, 99, -9.512183070183e-01, 6.009868798174e-07, 1.5953e+02, 1.6187e+00, 1DIAGNOSTIC, 100, -9.512303471565e-01, 6.013098641233e-07, 1.6111e+02, 1.5775e+00, XXDIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 1DIAGNOSTIC, 1, -9.108011722565e-01, inf, 1.6909e+02, 7.9845e+00, 1DIAGNOSTIC, 2, -9.125345945358e-01, inf, 1.7598e+02, 6.8889e+00, 1DIAGNOSTIC, 3, -9.141367673874e-01, inf, 1.8296e+02, 6.9751e+00, 1DIAGNOSTIC, 4, -9.156799912453e-01, inf, 1.8988e+02, 6.9235e+00, 1DIAGNOSTIC, 5, -9.168740510941e-01, inf, 1.9695e+02, 7.0662e+00, 1DIAGNOSTIC, 6, -9.179238080978e-01, inf, 2.0385e+02, 6.9051e+00, 1DIAGNOSTIC, 7, -9.188411831856e-01, inf, 2.1087e+02, 7.0213e+00, 1DIAGNOSTIC, 8, -9.195513129234e-01, inf, 2.1789e+02, 7.0164e+00, 1DIAGNOSTIC, 9, -9.201766252518e-01, inf, 2.2485e+02, 6.9656e+00, 1DIAGNOSTIC, 10, -9.207194447517e-01, 6.866463809274e-04, 2.3176e+02, 6.9099e+00, 1DIAGNOSTIC, 11, -9.211903214455e-01, 5.371730076149e-04, 2.3864e+02, 6.8761e+00, 1DIAGNOSTIC, 12, -9.216108322144e-01, 4.197233647574e-04, 2.4548e+02, 6.8401e+00, 1DIAGNOSTIC, 13, -9.219734668732e-01, 3.288970328867e-04, 2.5252e+02, 7.0372e+00, 1DIAGNOSTIC, 14, -9.223276376724e-01, 2.629731025081e-04, 2.5945e+02, 6.9338e+00, 1DIAGNOSTIC, 15, -9.225355386734e-01, 2.105972234858e-04, 2.6650e+02, 7.0444e+00, 1DIAGNOSTIC, 16, -9.230003356934e-01, 1.746739435475e-04, 2.7347e+02, 6.9768e+00, 1DIAGNOSTIC, 17, -9.233994483948e-01, 1.506984845037e-04, 2.8050e+02, 7.0295e+00, 1DIAGNOSTIC, 18, -9.237971901894e-01, 1.344196061837e-04, 2.8744e+02, 6.9333e+00, 1DIAGNOSTIC, 19, -9.241442680359e-01, 1.232244976563e-04, 2.9449e+02, 7.0577e+00, 1DIAGNOSTIC, 20, -9.244889020920e-01, 1.154520796263e-04, 3.0157e+02, 7.0760e+00, 1DIAGNOSTIC, 21, -9.246650934219e-01, 1.071721999324e-04, 3.0856e+02, 6.9860e+00, 1DIAGNOSTIC, 22, -9.248782396317e-01, 9.856934048003e-05, 3.1556e+02, 7.0047e+00, 1DIAGNOSTIC, 23, -9.250330924988e-01, 8.847364370013e-05, 3.2276e+02, 7.1979e+00, 1DIAGNOSTIC, 24, -9.251878261566e-01, 7.758801802993e-05, 3.2968e+02, 6.9255e+00, 1DIAGNOSTIC, 25, -9.253316521645e-01, 6.465016485890e-05, 3.3655e+02, 6.8629e+00, 1DIAGNOSTIC, 26, -9.254829287529e-01, 5.399595102062e-05, 3.4301e+02, 6.4653e+00, 1DIAGNOSTIC, 27, -9.256012439728e-01, 4.500325667323e-05, 3.4953e+02, 6.5148e+00, 1DIAGNOSTIC, 28, -9.257757663727e-01, 3.876008122461e-05, 3.5595e+02, 6.4252e+00, 1DIAGNOSTIC, 29, -9.258903264999e-01, 3.420973371249e-05, 3.6255e+02, 6.5936e+00, 1DIAGNOSTIC, 30, -9.259555339813e-01, 3.101824040641e-05, 3.6905e+02, 6.5082e+00, 1DIAGNOSTIC, 31, -9.260536432266e-01, 2.789785503410e-05, 3.7561e+02, 6.5519e+00, 1DIAGNOSTIC, 32, -9.261274337769e-01, 2.515730193409e-05, 3.8214e+02, 6.5341e+00, 1DIAGNOSTIC, 33, -9.262201189995e-01, 2.256779043819e-05, 3.8866e+02, 6.5162e+00, 1DIAGNOSTIC, 34, -9.263415932655e-01, 2.055395634670e-05, 3.9516e+02, 6.5066e+00, 1DIAGNOSTIC, 35, -9.264171719551e-01, 1.869636071206e-05, 4.0176e+02, 6.6013e+00, 1DIAGNOSTIC, 36, -9.265394806862e-01, 1.758614598657e-05, 4.0830e+02, 6.5359e+00, 1DIAGNOSTIC, 37, -9.266020059586e-01, 1.641012931941e-05, 4.1475e+02, 6.4556e+00, 1DIAGNOSTIC, 38, -9.266311526299e-01, 1.544825499877e-05, 4.2145e+02, 6.6966e+00, 1DIAGNOSTIC, 39, -9.266883134842e-01, 1.449800492992e-05, 4.2809e+02, 6.6351e+00, 1DIAGNOSTIC, 40, -9.267181754112e-01, 1.300090571021e-05, 4.3459e+02, 6.5029e+00, 1DIAGNOSTIC, 41, -9.267778396606e-01, 1.158805480372e-05, 4.4121e+02, 6.6246e+00, 1DIAGNOSTIC, 42, -9.268846511841e-01, 1.052004517987e-05, 4.4772e+02, 6.5100e+00, 1DIAGNOSTIC, 43, -9.269333481789e-01, 9.557712473907e-06, 4.5431e+02, 6.5847e+00, 1DIAGNOSTIC, 44, -9.270129203796e-01, 9.203382433043e-06, 4.6085e+02, 6.5413e+00, 1DIAGNOSTIC, 45, -9.270517826080e-01, 8.815258297545e-06, 4.6746e+02, 6.6140e+00, 1DIAGNOSTIC, 46, -9.270620942116e-01, 8.546615390514e-06, 4.7406e+02, 6.5993e+00, 1DIAGNOSTIC, 47, -9.271082878113e-01, 8.247056939581e-06, 4.8066e+02, 6.5987e+00, 1DIAGNOSTIC, 48, -9.271395206451e-01, 7.607040970470e-06, 4.8710e+02, 6.4413e+00, 1DIAGNOSTIC, 49, -9.271823763847e-01, 6.954749551369e-06, 4.9361e+02, 6.5044e+00, 1DIAGNOSTIC, 50, -9.272590875626e-01, 6.375868451869e-06, 5.0020e+02, 6.5919e+00, 1DIAGNOSTIC, 51, -9.272948503494e-01, 5.828161647514e-06, 5.0690e+02, 6.7030e+00, 1DIAGNOSTIC, 52, -9.272840023041e-01, 5.369505288400e-06, 5.1353e+02, 6.6307e+00, 1DIAGNOSTIC, 53, -9.273270964622e-01, 5.001635145163e-06, 5.2007e+02, 6.5326e+00, 1DIAGNOSTIC, 54, -9.273964166641e-01, 5.061018782726e-06, 5.2678e+02, 6.7167e+00, 1DIAGNOSTIC, 55, -9.274373054504e-01, 5.121233243699e-06, 5.3324e+02, 6.4597e+00, 1DIAGNOSTIC, 56, -9.274214506149e-01, 4.708634605777e-06, 5.3969e+02, 6.4500e+00, 1DIAGNOSTIC, 57, -9.274669289589e-01, 4.422766778589e-06, 5.4638e+02, 6.6923e+00, 1DIAGNOSTIC, 58, -9.274432063103e-01, 3.807408120338e-06, 5.5297e+02, 6.5851e+00, 1DIAGNOSTIC, 59, -9.274988770485e-01, 3.400470632187e-06, 5.5959e+02, 6.6214e+00, 1DIAGNOSTIC, 60, -9.275195002556e-01, 3.218222445867e-06, 5.6626e+02, 6.6644e+00, 1DIAGNOSTIC, 61, -9.275590181351e-01, 3.171029675286e-06, 5.7328e+02, 7.0238e+00, 1DIAGNOSTIC, 62, -9.276278614998e-01, 3.156523007419e-06, 5.8036e+02, 7.0788e+00, 1DIAGNOSTIC, 63, -9.276663661003e-01, 3.272269623267e-06, 5.8754e+02, 7.1835e+00, 1DIAGNOSTIC, 64, -9.276365041733e-01, 3.301993501736e-06, 5.9458e+02, 7.0350e+00, 1DIAGNOSTIC, 65, -9.276769757271e-01, 3.456702870608e-06, 6.0164e+02, 7.0674e+00, 1DIAGNOSTIC, 66, -9.277353882790e-01, 3.507226665533e-06, 6.0887e+02, 7.2225e+00, 1DIAGNOSTIC, 67, -9.276953339577e-01, 3.283211299276e-06, 6.1589e+02, 7.0207e+00, 1DIAGNOSTIC, 68, -9.277479052544e-01, 2.930244590971e-06, 6.2303e+02, 7.1399e+00, 1DIAGNOSTIC, 69, -9.277855157852e-01, 2.766613761196e-06, 6.3029e+02, 7.2597e+00, 1DIAGNOSTIC, 70, -9.277557134628e-01, 2.338381818845e-06, 6.3733e+02, 7.0422e+00, 1DIAGNOSTIC, 71, -9.277892112732e-01, 2.053188154605e-06, 6.4461e+02, 7.2783e+00, 1DIAGNOSTIC, 72, -9.278364181519e-01, 2.111214143952e-06, 6.5174e+02, 7.1327e+00, 1DIAGNOSTIC, 73, -9.278875589371e-01, 2.384015942880e-06, 6.5898e+02, 7.2434e+00, 1DIAGNOSTIC, 74, -9.278196096420e-01, 2.046400368272e-06, 6.6634e+02, 7.3555e+00, 1DIAGNOSTIC, 75, -9.278642535210e-01, 1.919895339597e-06, 6.7363e+02, 7.2880e+00, 1DIAGNOSTIC, 76, -9.279065132141e-01, 2.061494342342e-06, 6.8068e+02, 7.0498e+00, 1DIAGNOSTIC, 77, -9.279310703278e-01, 1.961388306881e-06, 6.8784e+02, 7.1666e+00, 1DIAGNOSTIC, 78, -9.278359413147e-01, 1.542382619846e-06, 6.9495e+02, 7.1096e+00, 1DIAGNOSTIC, 79, -9.278705120087e-01, 1.330600753136e-06, 7.0199e+02, 7.0358e+00, 1DIAGNOSTIC, 80, -9.279164671898e-01, 1.089152874556e-06, 7.0900e+02, 7.0065e+00, 1DIAGNOSTIC, 81, -9.279603958130e-01, 1.060643398887e-06, 7.1608e+02, 7.0817e+00, 1DIAGNOSTIC, 82, -9.279863834381e-01, 1.235430659108e-06, 7.2300e+02, 6.9271e+00, 1DIAGNOSTIC, 83, -9.279632568359e-01, 1.446732085242e-06, 7.3009e+02, 7.0836e+00, 1DIAGNOSTIC, 84, -9.279347062111e-01, 1.200828251058e-06, 7.3715e+02, 7.0664e+00, 1DIAGNOSTIC, 85, -9.279518723488e-01, 1.095395987250e-06, 7.4411e+02, 6.9587e+00, 1DIAGNOSTIC, 86, -9.279493093491e-01, 1.052038214766e-06, 7.5099e+02, 6.8792e+00, 1DIAGNOSTIC, 87, -9.279762506485e-01, 1.136888386100e-06, 7.5806e+02, 7.0694e+00, 1DIAGNOSTIC, 88, -9.279552102089e-01, 7.404528901134e-07, 7.6510e+02, 7.0422e+00, 1DIAGNOSTIC, 89, -9.279696941376e-01, 4.891916773886e-07, 7.7208e+02, 6.9720e+00, 1DIAGNOSTIC, 90, -9.279888868332e-01, 4.472836110381e-07, 7.7909e+02, 7.0154e+00, 1DIAGNOSTIC, 91, -9.279881715775e-01, 5.352763423616e-07, 7.8609e+02, 6.9977e+00, 1DIAGNOSTIC, 92, -9.280241727829e-01, 8.127806836455e-07, 7.9304e+02, 6.9464e+00, 1DIAGNOSTIC, 93, -9.280447959900e-01, 1.032443265103e-06, 8.0004e+02, 7.0062e+00, 1DIAGNOSTIC, 94, -9.280213713646e-01, 1.009320953926e-06, 8.0705e+02, 7.0061e+00, 1DIAGNOSTIC, 95, -9.280272126198e-01, 1.000030124487e-06, 8.1407e+02, 7.0204e+00, 1DIAGNOSTIC, 96, -9.280118942261e-01, 8.659280297252e-07, 8.2103e+02, 6.9601e+00, 1DIAGNOSTIC, 97, -9.280381798744e-01, 8.531017101632e-07, 8.2807e+02, 7.0395e+00, 1DIAGNOSTIC, 98, -9.280145168304e-01, 6.452418688241e-07, 8.3506e+02, 6.9908e+00, 1DIAGNOSTIC, 99, -9.278529286385e-01, -4.224306238143e-08, 8.4209e+02, 7.0284e+00, XXDIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 1DIAGNOSTIC, 1, -8.501801490784e-01, inf, 9.0061e+02, 5.8523e+01, 1DIAGNOSTIC, 2, -8.521333336830e-01, inf, 9.5873e+02, 5.8124e+01, 1DIAGNOSTIC, 3, -8.540108203888e-01, inf, 1.0158e+03, 5.7039e+01, 1DIAGNOSTIC, 4, -8.560948371887e-01, inf, 1.0715e+03, 5.5728e+01, 1DIAGNOSTIC, 5, -8.578430414200e-01, inf, 1.1272e+03, 5.5732e+01, 1DIAGNOSTIC, 6, -8.594943284988e-01, inf, 1.1847e+03, 5.7443e+01, 1DIAGNOSTIC, 7, -8.610307574272e-01, inf, 1.2411e+03, 5.6424e+01, 1DIAGNOSTIC, 8, -8.624705076218e-01, inf, 1.2951e+03, 5.3972e+01, 1DIAGNOSTIC, 9, -8.638159632683e-01, inf, 1.3486e+03, 5.3502e+01, 1DIAGNOSTIC, 10, -8.650807142258e-01, 1.116666826420e-03, 1.4023e+03, 5.3709e+01, 1DIAGNOSTIC, 11, -8.661897778511e-01, 9.523048065603e-04, 1.4567e+03, 5.4442e+01, 1DIAGNOSTIC, 12, -8.672332763672e-01, 8.120799902827e-04, 1.5129e+03, 5.6129e+01, 1DIAGNOSTIC, 13, -8.680823445320e-01, 6.887269555591e-04, 1.5676e+03, 5.4700e+01, 1DIAGNOSTIC, 14, -8.688367605209e-01, 5.870054010302e-04, 1.6212e+03, 5.3692e+01, 1DIAGNOSTIC, 15, -8.695427775383e-01, 4.989034496248e-04, 1.6745e+03, 5.3227e+01, 1DIAGNOSTIC, 16, -8.701996207237e-01, 4.233213257976e-04, 1.7289e+03, 5.4465e+01, 1DIAGNOSTIC, 17, -8.708255290985e-01, 3.593123401515e-04, 1.7844e+03, 5.5447e+01, 1DIAGNOSTIC, 18, -8.714023232460e-01, 3.059075970668e-04, 1.8390e+03, 5.4588e+01, 1DIAGNOSTIC, 19, -8.719716072083e-01, 2.627756039146e-04, 1.8943e+03, 5.5329e+01, 1DIAGNOSTIC, 20, -8.724954724312e-01, 2.288036484970e-04, 1.9493e+03, 5.5003e+01, 1DIAGNOSTIC, 21, -8.730161190033e-01, 2.021062246058e-04, 2.0046e+03, 5.5341e+01, 1DIAGNOSTIC, 22, -8.734942674637e-01, 1.815940340748e-04, 2.0592e+03, 5.4562e+01, 1DIAGNOSTIC, 23, -8.739790916443e-01, 1.648620964261e-04, 2.1139e+03, 5.4694e+01, 1DIAGNOSTIC, 24, -8.744277954102e-01, 1.504664105596e-04, 2.1695e+03, 5.5629e+01, 1DIAGNOSTIC, 25, -8.748829960823e-01, 1.382937480230e-04, 2.2247e+03, 5.5128e+01, 1DIAGNOSTIC, 26, -8.752951025963e-01, 1.274952082895e-04, 2.2798e+03, 5.5140e+01, 1DIAGNOSTIC, 27, -8.757046461105e-01, 1.180454273708e-04, 2.3353e+03, 5.5512e+01, 1DIAGNOSTIC, 28, -8.760616779327e-01, 1.090442092391e-04, 2.3907e+03, 5.5355e+01, 1DIAGNOSTIC, 29, -8.764266967773e-01, 1.009195329971e-04, 2.4460e+03, 5.5364e+01, 1DIAGNOSTIC, 30, -8.767379522324e-01, 9.289808804169e-05, 2.5011e+03, 5.5056e+01, 1DIAGNOSTIC, 31, -8.770507574081e-01, 8.541309944121e-05, 2.5557e+03, 5.4620e+01, 1DIAGNOSTIC, 32, -8.773211240768e-01, 7.796055433573e-05, 2.6103e+03, 5.4604e+01, 1DIAGNOSTIC, 33, -8.776051998138e-01, 7.120690861484e-05, 2.6648e+03, 5.4527e+01, 1DIAGNOSTIC, 34, -8.778394460678e-01, 6.466458580690e-05, 2.7195e+03, 5.4627e+01, 1DIAGNOSTIC, 35, -8.780910968781e-01, 5.897898518015e-05, 2.7741e+03, 5.4594e+01, 1DIAGNOSTIC, 36, -8.782909512520e-01, 5.357078043744e-05, 2.8283e+03, 5.4258e+01, 1DIAGNOSTIC, 37, -8.785169124603e-01, 4.900235944660e-05, 2.8827e+03, 5.4346e+01, 1DIAGNOSTIC, 38, -8.786931037903e-01, 4.460749551072e-05, 2.9374e+03, 5.4732e+01, 1DIAGNOSTIC, 39, -8.788906931877e-01, 4.093433017260e-05, 2.9922e+03, 5.4770e+01, 1DIAGNOSTIC, 40, -8.790463209152e-01, 3.737843871932e-05, 3.0469e+03, 5.4726e+01, 1DIAGNOSTIC, 41, -8.792237639427e-01, 3.437322084210e-05, 3.1024e+03, 5.5483e+01, 1DIAGNOSTIC, 42, -8.793598413467e-01, 3.141469278489e-05, 3.1575e+03, 5.5123e+01, 1DIAGNOSTIC, 43, -8.795201778412e-01, 2.900820618379e-05, 3.2119e+03, 5.4396e+01, 1DIAGNOSTIC, 44, -8.796366453171e-01, 2.656903052412e-05, 3.2669e+03, 5.5012e+01, 1DIAGNOSTIC, 45, -8.797814846039e-01, 2.461821713950e-05, 3.3209e+03, 5.3967e+01, 1DIAGNOSTIC, 46, -8.798877000809e-01, 2.259805114591e-05, 3.3751e+03, 5.4194e+01, 1DIAGNOSTIC, 47, -8.800174593925e-01, 2.101474638039e-05, 3.4302e+03, 5.5119e+01, 1DIAGNOSTIC, 48, -8.801065683365e-01, 1.932146187755e-05, 3.4856e+03, 5.5447e+01, 1DIAGNOSTIC, 49, -8.802273869514e-01, 1.801242069632e-05, 3.5406e+03, 5.4970e+01, 1DIAGNOSTIC, 50, -8.803084492683e-01, 1.660668203840e-05, 3.5963e+03, 5.5713e+01, 1DIAGNOSTIC, 51, -8.804155588150e-01, 1.552892717882e-05, 3.6512e+03, 5.4881e+01, 1DIAGNOSTIC, 52, -8.804829716682e-01, 1.431432792742e-05, 3.7059e+03, 5.4681e+01, 1DIAGNOSTIC, 53, -8.805857300758e-01, 1.343841540802e-05, 3.7624e+03, 5.6541e+01, 1DIAGNOSTIC, 54, -8.806484937668e-01, 1.242121470568e-05, 3.8181e+03, 5.5672e+01, 1DIAGNOSTIC, 55, -8.807437419891e-01, 1.171676012746e-05, 3.8735e+03, 5.5388e+01, 1DIAGNOSTIC, 56, -8.808032274246e-01, 1.091211015591e-05, 3.9283e+03, 5.4825e+01, 1DIAGNOSTIC, 57, -8.808814287186e-01, 1.032291675074e-05, 3.9830e+03, 5.4685e+01, 1DIAGNOSTIC, 58, -8.809357881546e-01, 9.604650585970e-06, 4.0387e+03, 5.5703e+01, 1DIAGNOSTIC, 59, -8.810074329376e-01, 9.094479537453e-06, 4.0935e+03, 5.4785e+01, 1DIAGNOSTIC, 60, -8.810573220253e-01, 8.474139576720e-06, 4.1485e+03, 5.4994e+01, 1DIAGNOSTIC, 61, -8.811246156693e-01, 8.035181053856e-06, 4.2036e+03, 5.5108e+01, 1DIAGNOSTIC, 62, -8.811567425728e-01, 7.396755790978e-06, 4.2585e+03, 5.4967e+01, 1DIAGNOSTIC, 63, -8.812310695648e-01, 7.028329946479e-06, 4.3136e+03, 5.5043e+01, 1DIAGNOSTIC, 64, -8.812598586082e-01, 6.493859473267e-06, 4.3678e+03, 5.4231e+01, 1DIAGNOSTIC, 65, -8.813258409500e-01, 6.202063559613e-06, 4.4231e+03, 5.5249e+01, 1DIAGNOSTIC, 66, -8.813476562500e-01, 5.758948645962e-06, 4.4780e+03, 5.4927e+01, 1DIAGNOSTIC, 67, -8.814113140106e-01, 5.507778041647e-06, 4.5330e+03, 5.5007e+01, 1DIAGNOSTIC, 68, -8.814331293106e-01, 5.132379101269e-06, 4.5875e+03, 5.4523e+01, 1DIAGNOSTIC, 69, -8.814902305603e-01, 4.922142579744e-06, 4.6412e+03, 5.3720e+01, 1DIAGNOSTIC, 70, -8.815082907677e-01, 4.594494839694e-06, 4.6955e+03, 5.4306e+01, XXDIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 1DIAGNOSTIC, 1, -7.830697894096e-01, inf, 4.9134e+03, 2.1781e+02, 1DIAGNOSTIC, 2, -7.830060720444e-01, inf, 5.1287e+03, 2.1533e+02, 1DIAGNOSTIC, 3, -7.831569910049e-01, inf, 5.3440e+03, 2.1527e+02, 1DIAGNOSTIC, 4, -7.833789587021e-01, inf, 5.5553e+03, 2.1136e+02, 1DIAGNOSTIC, 5, -7.835031747818e-01, inf, 5.7643e+03, 2.0893e+02, 1DIAGNOSTIC, 6, -7.836358547211e-01, inf, 5.9883e+03, 2.2405e+02, 1DIAGNOSTIC, 7, -7.837456464767e-01, inf, 6.2098e+03, 2.2148e+02, 1DIAGNOSTIC, 8, -7.838439941406e-01, inf, 6.4317e+03, 2.2196e+02, 1DIAGNOSTIC, 9, -7.839308977127e-01, inf, 6.6533e+03, 2.2157e+02, 1DIAGNOSTIC, 10, -7.840101718903e-01, 9.109926759265e-05, 6.8686e+03, 2.1527e+02, 1DIAGNOSTIC, 11, -7.840864062309e-01, 8.171311492333e-05, 7.0815e+03, 2.1292e+02, 1DIAGNOSTIC, 12, -7.842146158218e-01, 6.870829383843e-05, 7.2923e+03, 2.1078e+02, 1DIAGNOSTIC, 13, -7.843473553658e-01, 5.947102908976e-05, 7.4960e+03, 2.0376e+02, 1DIAGNOSTIC, 14, -7.844830751419e-01, 5.555377720157e-05, 7.7020e+03, 2.0596e+02, 1DIAGNOSTIC, 15, -7.846267223358e-01, 5.369692007662e-05, 7.9201e+03, 2.1810e+02, 1DIAGNOSTIC, 16, -7.847180366516e-01, 5.235255230218e-05, 8.1464e+03, 2.2633e+02, 1DIAGNOSTIC, 17, -7.848238945007e-01, 5.108422192279e-05, 8.3714e+03, 2.2492e+02, 1DIAGNOSTIC, 18, -7.848795056343e-01, 4.844898649026e-05, 8.6070e+03, 2.3567e+02, 1DIAGNOSTIC, 19, -7.849998474121e-01, 4.569255179376e-05, 8.8268e+03, 2.1972e+02, 1DIAGNOSTIC, 20, -7.850781679153e-01, 4.192738560960e-05, 9.0492e+03, 2.2242e+02, Elapsed time (stage 2): 9056

Total elapsed time: 9163 Using single precision for computations. Input scalar image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template02000008Repaired.nii.gz Reference image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz

The composite transform comprises the following transforms (in order):

/media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000830GenericAffine.mat (type = AffineTransform)
/media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000831Warp.nii.gz (type = DisplacementFieldTransform)

Default pixel value: 0 Interpolation type: LinearInterpolateImageFunction Output warped image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template020000083WarpedToTemplate.nii.gz

Running N4 for 3-dimensional images.

Mask not read. Using the entire image as the mask.

Original intensity range: [0, 2550]

Warning: Your input image contains nonpositive values which could cause failure or problematic results. A possible workaround would be to:

rescale your image to positive values e.g., [10,100].
run N4 on your rescaled image.
(optional) rescale the N4 output to the original intensity range.

Specified spline distance: 200mm original image size: [180, 512, 512] padded image size: [334, 854, 854] number of control points: [5, 5, 5]

Current level = 1 Iteration 1 (of 50). Current convergence value = 0.000172252 (threshold = 1e-08) Iteration 2 (of 50). Current convergence value = 0.000153995 (threshold = 1e-08) Iteration 3 (of 50). Current convergence value = 0.000140152 (threshold = 1e-08) Iteration 4 (of 50). Current convergence value = 0.000130068 (threshold = 1e-08) Iteration 5 (of 50). Current convergence value = 0.000121748 (threshold = 1e-08) Iteration 6 (of 50). Current convergence value = 0.000115064 (threshold = 1e-08) Iteration 7 (of 50). Current convergence value = 0.000109514 (threshold = 1e-08) Iteration 8 (of 50). Current convergence value = 0.00010467 (threshold = 1e-08) Iteration 9 (of 50). Current convergence value = 0.000100544 (threshold = 1e-08) Iteration 10 (of 50). Current convergence value = 9.67493e-05 (threshold = 1e-08) Iteration 11 (of 50). Current convergence value = 9.33741e-05 (threshold = 1e-08) Iteration 12 (of 50). Current convergence value = 9.023e-05 (threshold = 1e-08) Iteration 13 (of 50). Current convergence value = 8.71644e-05 (threshold = 1e-08) Iteration 14 (of 50). Current convergence value = 8.44563e-05 (threshold = 1e-08) Iteration 15 (of 50). Current convergence value = 8.19606e-05 (threshold = 1e-08) Iteration 16 (of 50). Current convergence value = 7.95647e-05 (threshold = 1e-08) Iteration 17 (of 50). Current convergence value = 7.71923e-05 (threshold = 1e-08) Iteration 18 (of 50). Current convergence value = 7.49197e-05 (threshold = 1e-08) Iteration 19 (of 50). Current convergence value = 7.28036e-05 (threshold = 1e-08) Iteration 20 (of 50). Current convergence value = 7.07102e-05 (threshold = 1e-08) Iteration 21 (of 50). Current convergence value = 6.88145e-05 (threshold = 1e-08) Iteration 22 (of 50). Current convergence value = 6.69673e-05 (threshold = 1e-08) Iteration 23 (of 50). Current convergence value = 6.51371e-05 (threshold = 1e-08) Iteration 24 (of 50). Current convergence value = 6.32908e-05 (threshold = 1e-08) Iteration 25 (of 50). Current convergence value = 6.15707e-05 (threshold = 1e-08) Iteration 26 (of 50). Current convergence value = 5.99744e-05 (threshold = 1e-08) Iteration 27 (of 50). Current convergence value = 5.83836e-05 (threshold = 1e-08) Iteration 28 (of 50). Current convergence value = 5.67237e-05 (threshold = 1e-08) Iteration 29 (of 50). Current convergence value = 5.52098e-05 (threshold = 1e-08) Iteration 30 (of 50). Current convergence value = 5.37875e-05 (threshold = 1e-08) Iteration 31 (of 50). Current convergence value = 5.24123e-05 (threshold = 1e-08) Iteration 32 (of 50). Current convergence value = 5.10945e-05 (threshold = 1e-08) Iteration 33 (of 50). Current convergence value = 4.98502e-05 (threshold = 1e-08) Iteration 34 (of 50). Current convergence value = 4.86352e-05 (threshold = 1e-08) Iteration 35 (of 50). Current convergence value = 4.74674e-05 (threshold = 1e-08) Iteration 36 (of 50). Current convergence value = 4.62844e-05 (threshold = 1e-08) Iteration 37 (of 50). Current convergence value = 4.52408e-05 (threshold = 1e-08) Iteration 38 (of 50). Current convergence value = 4.42519e-05 (threshold = 1e-08) Iteration 39 (of 50). Current convergence value = 4.31881e-05 (threshold = 1e-08) Iteration 40 (of 50). Current convergence value = 4.21586e-05 (threshold = 1e-08) Iteration 41 (of 50). Current convergence value = 4.11723e-05 (threshold = 1e-08) Iteration 42 (of 50). Current convergence value = 4.02442e-05 (threshold = 1e-08) Iteration 43 (of 50). Current convergence value = 3.93278e-05 (threshold = 1e-08) Iteration 44 (of 50). Current convergence value = 3.84021e-05 (threshold = 1e-08) Iteration 45 (of 50). Current convergence value = 3.75532e-05 (threshold = 1e-08) Iteration 46 (of 50). Current convergence value = 3.67026e-05 (threshold = 1e-08) Iteration 47 (of 50). Current convergence value = 3.5931e-05 (threshold = 1e-08) Iteration 48 (of 50). Current convergence value = 3.503e-05 (threshold = 1e-08) Iteration 49 (of 50). Current convergence value = 3.42655e-05 (threshold = 1e-08) Iteration 50 (of 50). Current convergence value = 3.34453e-05 (threshold = 1e-08) Current level = 2 Iteration 1 (of 50). Current convergence value = 0.000215757 (threshold = 1e-08) Iteration 2 (of 50). Current convergence value = 0.000221281 (threshold = 1e-08) Iteration 3 (of 50). Current convergence value = 0.000221613 (threshold = 1e-08) Iteration 4 (of 50). Current convergence value = 0.00021899 (threshold = 1e-08) Iteration 5 (of 50). Current convergence value = 0.000214425 (threshold = 1e-08) Iteration 6 (of 50). Current convergence value = 0.000209389 (threshold = 1e-08) Iteration 7 (of 50). Current convergence value = 0.00020603 (threshold = 1e-08) Iteration 8 (of 50). Current convergence value = 0.000202568 (threshold = 1e-08) Iteration 9 (of 50). Current convergence value = 0.000199195 (threshold = 1e-08) Iteration 10 (of 50). Current convergence value = 0.000194181 (threshold = 1e-08) Iteration 11 (of 50). Current convergence value = 0.000192553 (threshold = 1e-08) Iteration 12 (of 50). Current convergence value = 0.000191001 (threshold = 1e-08) Iteration 13 (of 50). Current convergence value = 0.000188483 (threshold = 1e-08) Iteration 14 (of 50). Current convergence value = 0.000185091 (threshold = 1e-08) Iteration 15 (of 50). Current convergence value = 0.000180587 (threshold = 1e-08) Iteration 16 (of 50). Current convergence value = 0.000175869 (threshold = 1e-08) Iteration 17 (of 50). Current convergence value = 0.000172981 (threshold = 1e-08) Iteration 18 (of 50). Current convergence value = 0.000170318 (threshold = 1e-08) Iteration 19 (of 50). Current convergence value = 0.000166577 (threshold = 1e-08) Iteration 20 (of 50). Current convergence value = 0.000161024 (threshold = 1e-08) Iteration 21 (of 50). Current convergence value = 0.000155326 (threshold = 1e-08) Iteration 22 (of 50). Current convergence value = 0.000150329 (threshold = 1e-08) Iteration 23 (of 50). Current convergence value = 0.000146622 (threshold = 1e-08) Iteration 24 (of 50). Current convergence value = 0.000142424 (threshold = 1e-08) Iteration 25 (of 50). Current convergence value = 0.000139353 (threshold = 1e-08) Iteration 26 (of 50). Current convergence value = 0.000136561 (threshold = 1e-08) Iteration 27 (of 50). Current convergence value = 0.000135059 (threshold = 1e-08) Iteration 28 (of 50). Current convergence value = 0.000134162 (threshold = 1e-08) Iteration 29 (of 50). Current convergence value = 0.00013326 (threshold = 1e-08) Iteration 30 (of 50). Current convergence value = 0.000132047 (threshold = 1e-08) Iteration 31 (of 50). Current convergence value = 0.000130893 (threshold = 1e-08) Iteration 32 (of 50). Current convergence value = 0.000129847 (threshold = 1e-08) Iteration 33 (of 50). Current convergence value = 0.000129219 (threshold = 1e-08) Iteration 34 (of 50). Current convergence value = 0.000128546 (threshold = 1e-08) Iteration 35 (of 50). Current convergence value = 0.000128046 (threshold = 1e-08) Iteration 36 (of 50). Current convergence value = 0.000127683 (threshold = 1e-08) Iteration 37 (of 50). Current convergence value = 0.000127038 (threshold = 1e-08) Iteration 38 (of 50). Current convergence value = 0.000126082 (threshold = 1e-08) Iteration 39 (of 50). Current convergence value = 0.000124943 (threshold = 1e-08) Iteration 40 (of 50). Current convergence value = 0.000123671 (threshold = 1e-08) Iteration 41 (of 50). Current convergence value = 0.000122354 (threshold = 1e-08) Iteration 42 (of 50). Current convergence value = 0.000120915 (threshold = 1e-08) Iteration 43 (of 50). Current convergence value = 0.000119175 (threshold = 1e-08) Iteration 44 (of 50). Current convergence value = 0.000117649 (threshold = 1e-08) Iteration 45 (of 50). Current convergence value = 0.000116043 (threshold = 1e-08) Iteration 46 (of 50). Current convergence value = 0.000114418 (threshold = 1e-08) Iteration 47 (of 50). Current convergence value = 0.000112821 (threshold = 1e-08) Iteration 48 (of 50). Current convergence value = 0.000111437 (threshold = 1e-08) Iteration 49 (of 50). Current convergence value = 0.000110103 (threshold = 1e-08) Iteration 50 (of 50). Current convergence value = 0.000108989 (threshold = 1e-08) Current level = 3 Iteration 1 (of 40). Current convergence value = 0.000583893 (threshold = 1e-08) Iteration 2 (of 40). Current convergence value = 0.000521669 (threshold = 1e-08) Iteration 3 (of 40). Current convergence value = 0.000493111 (threshold = 1e-08) Iteration 4 (of 40). Current convergence value = 0.000465624 (threshold = 1e-08) Iteration 5 (of 40). Current convergence value = 0.000453099 (threshold = 1e-08) Iteration 6 (of 40). Current convergence value = 0.000444686 (threshold = 1e-08) Iteration 7 (of 40). Current convergence value = 0.000486286 (threshold = 1e-08) Iteration 8 (of 40). Current convergence value = 0.000458099 (threshold = 1e-08) Iteration 9 (of 40). Current convergence value = 0.000556026 (threshold = 1e-08) Iteration 10 (of 40). Current convergence value = 0.000607966 (threshold = 1e-08) Iteration 11 (of 40). Current convergence value = 0.000533477 (threshold = 1e-08) Iteration 12 (of 40). Current convergence value = 0.000490158 (threshold = 1e-08) Iteration 13 (of 40). Current convergence value = 0.000499308 (threshold = 1e-08) Iteration 14 (of 40). Current convergence value = 0.00045559 (threshold = 1e-08) Iteration 15 (of 40). Current convergence value = 0.000424527 (threshold = 1e-08) Iteration 16 (of 40). Current convergence value = 0.000418245 (threshold = 1e-08) Iteration 17 (of 40). Current convergence value = 0.000417938 (threshold = 1e-08) Iteration 18 (of 40). Current convergence value = 0.000411311 (threshold = 1e-08) Iteration 19 (of 40). Current convergence value = 0.000412899 (threshold = 1e-08) Iteration 20 (of 40). Current convergence value = 0.000414345 (threshold = 1e-08) Iteration 21 (of 40). Current convergence value = 0.000420702 (threshold = 1e-08) Iteration 22 (of 40). Current convergence value = 0.000427911 (threshold = 1e-08) Iteration 23 (of 40). Current convergence value = 0.000434455 (threshold = 1e-08) Iteration 24 (of 40). Current convergence value = 0.000445817 (threshold = 1e-08) Iteration 25 (of 40). Current convergence value = 0.00045746 (threshold = 1e-08) Iteration 26 (of 40). Current convergence value = 0.000459467 (threshold = 1e-08) Iteration 27 (of 40). Current convergence value = 0.000442658 (threshold = 1e-08) Iteration 28 (of 40). Current convergence value = 0.000440652 (threshold = 1e-08) Iteration 29 (of 40). Current convergence value = 0.000442522 (threshold = 1e-08) Iteration 30 (of 40). Current convergence value = 0.000430071 (threshold = 1e-08) Iteration 31 (of 40). Current convergence value = 0.000430228 (threshold = 1e-08) Iteration 32 (of 40). Current convergence value = 0.000450966 (threshold = 1e-08) Iteration 33 (of 40). Current convergence value = 0.000431788 (threshold = 1e-08) Iteration 34 (of 40). Current convergence value = 0.000410881 (threshold = 1e-08) Iteration 35 (of 40). Current convergence value = 0.000380892 (threshold = 1e-08) Iteration 36 (of 40). Current convergence value = 0.000364637 (threshold = 1e-08) Iteration 37 (of 40). Current convergence value = 0.000357975 (threshold = 1e-08) Iteration 38 (of 40). Current convergence value = 0.000357406 (threshold = 1e-08) Iteration 39 (of 40). Current convergence value = 0.000353827 (threshold = 1e-08) Iteration 40 (of 40). Current convergence value = 0.000378528 (threshold = 1e-08) Current level = 4 Iteration 1 (of 30). Current convergence value = 0.00135809 (threshold = 1e-08) Iteration 2 (of 30). Current convergence value = 0.00117888 (threshold = 1e-08) Iteration 3 (of 30). Current convergence value = 0.00111071 (threshold = 1e-08) Iteration 4 (of 30). Current convergence value = 0.00109352 (threshold = 1e-08) Iteration 5 (of 30). Current convergence value = 0.00108434 (threshold = 1e-08) Iteration 6 (of 30). Current convergence value = 0.00108444 (threshold = 1e-08) Iteration 7 (of 30). Current convergence value = 0.00108969 (threshold = 1e-08) Iteration 8 (of 30). Current convergence value = 0.00108601 (threshold = 1e-08) Iteration 9 (of 30). Current convergence value = 0.0010766 (threshold = 1e-08) Iteration 10 (of 30). Current convergence value = 0.00106121 (threshold = 1e-08) Iteration 11 (of 30). Current convergence value = 0.0010563 (threshold = 1e-08) Iteration 12 (of 30). Current convergence value = 0.00104221 (threshold = 1e-08) Iteration 13 (of 30). Current convergence value = 0.00108175 (threshold = 1e-08) Iteration 14 (of 30). Current convergence value = 0.00107066 (threshold = 1e-08) Iteration 15 (of 30). Current convergence value = 0.00102769 (threshold = 1e-08) Iteration 16 (of 30). Current convergence value = 0.00101518 (threshold = 1e-08) Iteration 17 (of 30). Current convergence value = 0.00100777 (threshold = 1e-08) Iteration 18 (of 30). Current convergence value = 0.000995623 (threshold = 1e-08) Iteration 19 (of 30). Current convergence value = 0.000996468 (threshold = 1e-08) Iteration 20 (of 30). Current convergence value = 0.00100585 (threshold = 1e-08) Iteration 21 (of 30). Current convergence value = 0.00100719 (threshold = 1e-08) Iteration 22 (of 30). Current convergence value = 0.000998888 (threshold = 1e-08) Iteration 23 (of 30). Current convergence value = 0.000990084 (threshold = 1e-08) Iteration 24 (of 30). Current convergence value = 0.000989406 (threshold = 1e-08) Iteration 25 (of 30). Current convergence value = 0.000969577 (threshold = 1e-08) Iteration 26 (of 30). Current convergence value = 0.000957375 (threshold = 1e-08) Iteration 27 (of 30). Current convergence value = 0.00100355 (threshold = 1e-08) Iteration 28 (of 30). Current convergence value = 0.00105447 (threshold = 1e-08) Iteration 29 (of 30). Current convergence value = 0.00105536 (threshold = 1e-08) Iteration 30 (of 30). Current convergence value = 0.000992006 (threshold = 1e-08) N4BiasFieldCorrectionImageFilter (0x5609139cc560) RTTI typeinfo: itk::N4BiasFieldCorrectionImageFilter<itk::Image<float, 3u>, itk::Image<float, 3u>, itk::Image<float, 3u> > Reference Count: 1 Modified Time: 579 Debug: Off Object Name: Observers: IterationEvent(Command) Inputs: ConfidenceImage: (0) MaskImage: (0x560913a029d0) Primary: (0x5609139fafe0) * Indexed Inputs: 0: Primary (0x5609139fafe0) 1: MaskImage (0x560913a029d0) 2: ConfidenceImage (0) Required Input Names: Primary NumberOfRequiredInputs: 1 Outputs: Primary: (0x5609139db730) Indexed Outputs: 0: Primary (0x5609139db730) NumberOfRequiredOutputs: 1 Number Of Work Units: 64 ReleaseDataFlag: Off ReleaseDataBeforeUpdateFlag: Off AbortGenerateData: Off Progress: 0 Multithreader: RTTI typeinfo: itk::PoolMultiThreader Reference Count: 1 Modified Time: 144 Debug: Off Object Name: Observers: none Number of Work Units: 64 Number of Threads: 16 Global Maximum Number Of Threads: 128 Global Default Number Of Threads: 16 Global Default Threader Type: itk::MultiThreaderBaseEnums::Threader::Pool SingleMethod: 0 SingleData: 0 DynamicMultiThreading: On CoordinateTolerance: 1e-06 DirectionTolerance: 1e-06 Use Mask Label: 0 Mask label: 1 Number of histogram bins: 200 Wiener filter noise: 0.01 Bias field FWHM: 0.15 Maximum number of iterations: [50, 50, 40, 30] Convergence threshold: 1e-08 Spline order: 3 Number of fitting levels: [4, 4, 4] Number of control points: [5, 5, 5] CurrentConvergenceMeasurement: 0.000992006 CurrentLevel: 4 ElapsedIterations: 31 LogBiasFieldControlPointLattice: Image (0x560913a22250) RTTI typeinfo: itk::Image<itk::Vector<float, 1u>, 3u> Reference Count: 1 Modified Time: 653462 Debug: Off Object Name: Observers: none Source: (none) Source output name: (none) Release Data: Off Data Released: False Global Release Data: Off PipelineMTime: 0 UpdateMTime: 0 RealTimeStamp: 0 seconds LargestPossibleRegion: Dimension: 3 Index: [0, 0, 0] Size: [19, 19, 19] BufferedRegion: Dimension: 3 Index: [0, 0, 0] Size: [19, 19, 19] RequestedRegion: Dimension: 3 Index: [0, 0, 0] Size: [19, 19, 19] Spacing: [24.8999, 24.9636, 24.9636] Origin: [-24.8999, 24.9636, -24.9636] Direction: 1 0 0 0 -1 0 0 0 1

     IndexToPointMatrix:

24.8999 0 0 0 -24.9636 0 0 0 24.9636

     PointToIndexMatrix:

0.0401607 0 0 0 -0.0400583 0 0 0 0.0400583

     Inverse Direction:

1 0 0 0 -1 0 0 0 1

     PixelContainer: 
       ImportImageContainer (0x56091944de60)
         RTTI typeinfo:   itk::ImportImageContainer<unsigned long, itk::Vector<float, 1u> >
         Reference Count: 1
         Modified Time: 653463
         Debug: Off
         Object Name: 
         Observers: 
           none
         Pointer: 0x56091d8525c0
         Container manages memory: true
         Size: 6859
         Capacity: 6859

Elapsed time: 484.465 All_Command_lines_OK Using single precision for computations.

The composite transform comprises the following transforms (in order):

Center of mass alignment using fixed image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz and moving image: /media/hwang/Disk1/brain_template_elderly/test//2000013.nii.gz (type = Euler3DTransform)

number of levels = 4 number of levels = 4 number of levels = 4 fixed image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz moving image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template02000013Repaired.nii.gz fixed image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz moving image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template02000013Repaired.nii.gz fixed image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz moving image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template02000013Repaired.nii.gz Dimension = 3 Number of stages = 3 Use Histogram Matching true Winsorize image intensities true Lower quantile = 0.01 Upper quantile = 0.99 Stage 1 State Image metric = Mattes Fixed image = Image (0x5616989c0640) RTTI typeinfo: itk::Image<float, 3u> Reference Count: 2 Modified Time: 1729 Debug: Off Object Name: Observers: none Source: (none) Source output name: (none) Release Data: Off Data Released: False Global Release Data: Off PipelineMTime: 0 UpdateMTime: 1512 RealTimeStamp: 0 seconds LargestPossibleRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] BufferedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] RequestedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] Spacing: [0.800003, 0.4688, 0.4688] Origin: [-102.283, 100.377, -103.987] Direction: 1 0 0 0 -1 0 0 0 1

IndexToPointMatrix: 0.800003 0 0 0 -0.4688 0 0 0 0.4688

PointToIndexMatrix: 1.25 0 0 0 -2.13311 0 0 0 2.13311

Inverse Direction: 1 0 0 0 -1 0 0 0 1

PixelContainer: ImportImageContainer (0x5616989c9180) RTTI typeinfo: itk::ImportImageContainer<unsigned long, float> Reference Count: 1 Modified Time: 1509 Debug: Off Object Name: Observers: none Pointer: 0x7fdecc16f010 Container manages memory: true Size: 63963136 Capacity: 63963136

Moving image = Image (0x5616989c4d30) RTTI typeinfo: itk::Image<float, 3u> Reference Count: 2 Modified Time: 1730 Debug: Off Object Name: Observers: none Source: (none) Source output name: (none) Release Data: Off Data Released: False Global Release Data: Off PipelineMTime: 0 UpdateMTime: 1727 RealTimeStamp: 0 seconds LargestPossibleRegion: Dimension: 3 Index: [0, 0, 0] Size: [180, 512, 512] BufferedRegion: Dimension: 3 Index: [0, 0, 0] Size: [180, 512, 512] RequestedRegion: Dimension: 3 Index: [0, 0, 0] Size: [180, 512, 512] Spacing: [1.2, 0.4688, 0.4688] Origin: [-109.74, 98.6208, -132.67] Direction: 1 0 0 0 -1 0 0 0 1

IndexToPointMatrix: 1.2 0 0 0 -0.4688 0 0 0 0.4688

PointToIndexMatrix: 0.833335 0 0 0 -2.13311 0 0 0 2.13311

Inverse Direction: 1 0 0 0 -1 0 0 0 1

PixelContainer: ImportImageContainer (0x5616989c0e70) RTTI typeinfo: itk::ImportImageContainer<unsigned long, float> Reference Count: 1 Modified Time: 1724 Debug: Off Object Name: Observers: none Pointer: 0x7fdec0d6e010 Container manages memory: true Size: 47185920 Capacity: 47185920

Weighting = 1 Sampling strategy = regular Number of bins = 32 Radius = 4 Sampling percentage = 0.25 Transform = Rigid Gradient step = 0.1 Update field sigma (voxel space) = 0 Total field sigma (voxel space) = 0 Update field time sigma = 0 Total field time sigma = 0 Number of time indices = 0 Number of time point samples = 0 Stage 2 State Image metric = Mattes Fixed image = Image (0x5616989d91f0) RTTI typeinfo: itk::Image<float, 3u> Reference Count: 2 Modified Time: 2161 Debug: Off Object Name: Observers: none Source: (none) Source output name: (none) Release Data: Off Data Released: False Global Release Data: Off PipelineMTime: 0 UpdateMTime: 1944 RealTimeStamp: 0 seconds LargestPossibleRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] BufferedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] RequestedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] Spacing: [0.800003, 0.4688, 0.4688] Origin: [-102.283, 100.377, -103.987] Direction: 1 0 0 0 -1 0 0 0 1

IndexToPointMatrix: 0.800003 0 0 0 -0.4688 0 0 0 0.4688

PointToIndexMatrix: 1.25 0 0 0 -2.13311 0 0 0 2.13311

Inverse Direction: 1 0 0 0 -1 0 0 0 1

PixelContainer: ImportImageContainer (0x5616989c2860) RTTI typeinfo: itk::ImportImageContainer<unsigned long, float> Reference Count: 1 Modified Time: 1941 Debug: Off Object Name: Observers: none Pointer: 0x7fdeb196d010 Container manages memory: true Size: 63963136 Capacity: 63963136

Moving image = Image (0x5616989d8e40) RTTI typeinfo: itk::Image<float, 3u> Reference Count: 2 Modified Time: 2162 Debug: Off Object Name: Observers: none Source: (none) Source output name: (none) Release Data: Off Data Released: False Global Release Data: Off PipelineMTime: 0 UpdateMTime: 2159 RealTimeStamp: 0 seconds LargestPossibleRegion: Dimension: 3 Index: [0, 0, 0] Size: [180, 512, 512] BufferedRegion: Dimension: 3 Index: [0, 0, 0] Size: [180, 512, 512] RequestedRegion: Dimension: 3 Index: [0, 0, 0] Size: [180, 512, 512] Spacing: [1.2, 0.4688, 0.4688] Origin: [-109.74, 98.6208, -132.67] Direction: 1 0 0 0 -1 0 0 0 1

IndexToPointMatrix: 1.2 0 0 0 -0.4688 0 0 0 0.4688

PointToIndexMatrix: 0.833335 0 0 0 -2.13311 0 0 0 2.13311

Inverse Direction: 1 0 0 0 -1 0 0 0 1

PixelContainer: ImportImageContainer (0x5616989d82a0) RTTI typeinfo: itk::ImportImageContainer<unsigned long, float> Reference Count: 1 Modified Time: 2156 Debug: Off Object Name: Observers: none Pointer: 0x7fdea656c010 Container manages memory: true Size: 47185920 Capacity: 47185920

Weighting = 1 Sampling strategy = regular Number of bins = 32 Radius = 4 Sampling percentage = 0.25 Transform = Affine Gradient step = 0.1 Update field sigma (voxel space) = 0 Total field sigma (voxel space) = 0 Update field time sigma = 0 Total field time sigma = 0 Number of time indices = 0 Number of time point samples = 0 Stage 3 State Image metric = CC Fixed image = Image (0x5616989de1c0) RTTI typeinfo: itk::Image<float, 3u> Reference Count: 2 Modified Time: 2593 Debug: Off Object Name: Observers: none Source: (none) Source output name: (none) Release Data: Off Data Released: False Global Release Data: Off PipelineMTime: 0 UpdateMTime: 2376 RealTimeStamp: 0 seconds LargestPossibleRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] BufferedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] RequestedRegion: Dimension: 3 Index: [0, 0, 0] Size: [244, 512, 512] Spacing: [0.800003, 0.4688, 0.4688] Origin: [-102.283, 100.377, -103.987] Direction: 1 0 0 0 -1 0 0 0 1

IndexToPointMatrix: 0.800003 0 0 0 -0.4688 0 0 0 0.4688

PointToIndexMatrix: 1.25 0 0 0 -2.13311 0 0 0 2.13311

Inverse Direction: 1 0 0 0 -1 0 0 0 1

PixelContainer: ImportImageContainer (0x5616989ddff0) RTTI typeinfo: itk::ImportImageContainer<unsigned long, float> Reference Count: 1 Modified Time: 2373 Debug: Off Object Name: Observers: none Pointer: 0x7fde9716b010 Container manages memory: true Size: 63963136 Capacity: 63963136

Moving image = Image (0x5616989e10b0) RTTI typeinfo: itk::Image<float, 3u> Reference Count: 2 Modified Time: 2594 Debug: Off Object Name: Observers: none Source: (none) Source output name: (none) Release Data: Off Data Released: False Global Release Data: Off PipelineMTime: 0 UpdateMTime: 2591 RealTimeStamp: 0 seconds LargestPossibleRegion: Dimension: 3 Index: [0, 0, 0] Size: [180, 512, 512] BufferedRegion: Dimension: 3 Index: [0, 0, 0] Size: [180, 512, 512] RequestedRegion: Dimension: 3 Index: [0, 0, 0] Size: [180, 512, 512] Spacing: [1.2, 0.4688, 0.4688] Origin: [-109.74, 98.6208, -132.67] Direction: 1 0 0 0 -1 0 0 0 1

IndexToPointMatrix: 1.2 0 0 0 -0.4688 0 0 0 0.4688

PointToIndexMatrix: 0.833335 0 0 0 -2.13311 0 0 0 2.13311

Inverse Direction: 1 0 0 0 -1 0 0 0 1

PixelContainer: ImportImageContainer (0x5616989c4310) RTTI typeinfo: itk::ImportImageContainer<unsigned long, float> Reference Count: 1 Modified Time: 2588 Debug: Off Object Name: Observers: none Pointer: 0x7fde8bd6a010 Container manages memory: true Size: 47185920 Capacity: 47185920

Weighting = 1 Sampling strategy = none Number of bins = 32 Radius = 4 Sampling percentage = 1 Transform = SyN Gradient step = 0.1 Update field sigma (voxel space) = 3 Total field sigma (voxel space) = 0 Update field time sigma = 0 Total field time sigma = 0 Number of time indices = 0 Number of time point samples = 0 Registration using 3 total stages.

Running Euler3DTransform registration

DIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 2DIAGNOSTIC, 1, -7.454515695572e-01, inf, 8.3993e-01, 8.3993e-01, 2DIAGNOSTIC, 2, -7.497540116310e-01, inf, 8.7040e-01, 3.0463e-02, 2DIAGNOSTIC, 3, -7.566450238228e-01, inf, 9.0101e-01, 3.0609e-02, 2DIAGNOSTIC, 4, -7.670708894730e-01, inf, 9.3063e-01, 2.9622e-02, 2DIAGNOSTIC, 5, -7.813651561737e-01, inf, 9.6131e-01, 3.0685e-02, 2DIAGNOSTIC, 6, -7.976804971695e-01, inf, 9.9190e-01, 3.0586e-02, 2DIAGNOSTIC, 7, -8.136537671089e-01, inf, 1.0230e+00, 3.1112e-02, 2DIAGNOSTIC, 8, -8.239006996155e-01, inf, 1.0546e+00, 3.1586e-02, 2DIAGNOSTIC, 9, -8.292434215546e-01, inf, 1.0942e+00, 3.9573e-02, 2DIAGNOSTIC, 10, -8.333867788315e-01, 8.245112374425e-03, 1.1298e+00, 3.5650e-02, 2DIAGNOSTIC, 11, -8.350882530212e-01, 7.114501670003e-03, 1.1571e+00, 2.7307e-02, 2DIAGNOSTIC, 12, -8.494450449944e-01, 6.087870802730e-03, 1.1884e+00, 3.1280e-02, 2DIAGNOSTIC, 13, -8.627553582191e-01, 5.213493481278e-03, 1.2163e+00, 2.7919e-02, 2DIAGNOSTIC, 14, -8.664450645447e-01, 4.348104353994e-03, 1.2486e+00, 3.2233e-02, 2DIAGNOSTIC, 15, -8.682616353035e-01, 3.588435007259e-03, 1.2760e+00, 2.7392e-02, 2DIAGNOSTIC, 16, -8.701815605164e-01, 2.996197668836e-03, 1.3123e+00, 3.6390e-02, 2DIAGNOSTIC, 17, -8.729590177536e-01, 2.576904604211e-03, 1.3438e+00, 3.1422e-02, 2DIAGNOSTIC, 18, -8.748793005943e-01, 2.195926615968e-03, 1.3758e+00, 3.1998e-02, 2DIAGNOSTIC, 19, -8.752556443214e-01, 1.758996513672e-03, 1.4284e+00, 5.2619e-02, 2DIAGNOSTIC, 20, -8.752550482750e-01, 1.282605924644e-03, 1.4597e+00, 3.1332e-02, 2DIAGNOSTIC, 21, -8.752512931824e-01, 7.594264461659e-04, 1.4906e+00, 3.0863e-02, 2DIAGNOSTIC, 22, -8.752529025078e-01, 4.330847004894e-04, 1.5260e+00, 3.5389e-02, 2DIAGNOSTIC, 23, -8.752521276474e-01, 2.920911938418e-04, 1.5608e+00, 3.4847e-02, 2DIAGNOSTIC, 24, -8.752495050430e-01, 1.885245292215e-04, 1.5997e+00, 3.8858e-02, 2DIAGNOSTIC, 25, -8.752471804619e-01, 1.008393155644e-04, 1.6342e+00, 3.4524e-02, 2DIAGNOSTIC, 26, -8.752479553223e-01, 3.523705890984e-05, 1.6641e+00, 2.9881e-02, 2DIAGNOSTIC, 27, -8.752459287643e-01, 5.657594556396e-06, 1.6938e+00, 2.9733e-02, DIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 2DIAGNOSTIC, 1, -7.912385463715e-01, inf, 2.8442e+00, 1.1504e+00, 2DIAGNOSTIC, 2, -7.912457585335e-01, inf, 2.9904e+00, 1.4625e-01, 2DIAGNOSTIC, 3, -7.912422418594e-01, inf, 3.1133e+00, 1.2282e-01, 2DIAGNOSTIC, 4, -7.912422418594e-01, inf, 3.2752e+00, 1.6196e-01, 2DIAGNOSTIC, 5, -7.912442088127e-01, inf, 3.4007e+00, 1.2550e-01, 2DIAGNOSTIC, 6, -7.912395000458e-01, inf, 3.5431e+00, 1.4240e-01, 2DIAGNOSTIC, 7, -7.912388443947e-01, inf, 3.6886e+00, 1.4548e-01, 2DIAGNOSTIC, 8, -7.912405133247e-01, inf, 3.8329e+00, 1.4430e-01, 2DIAGNOSTIC, 9, -7.912408709526e-01, inf, 3.9955e+00, 1.6256e-01, 2DIAGNOSTIC, 10, -7.912405133247e-01, 2.969773504446e-06, 4.1201e+00, 1.2466e-01, 2DIAGNOSTIC, 11, -7.912403941154e-01, 2.576041197244e-06, 4.2631e+00, 1.4302e-01, 2DIAGNOSTIC, 12, -7.912425398827e-01, 2.561150722613e-06, 4.4027e+00, 1.3952e-01, 2DIAGNOSTIC, 13, -7.912423014641e-01, 2.448784016451e-06, 4.5488e+00, 1.4612e-01, 2DIAGNOSTIC, 14, -7.912420034409e-01, 2.341982735743e-06, 4.6787e+00, 1.2991e-01, 2DIAGNOSTIC, 15, -7.912417054176e-01, 2.287802772116e-06, 4.8031e+00, 1.2444e-01, 2DIAGNOSTIC, 16, -7.912431955338e-01, 2.153730747523e-06, 4.9459e+00, 1.4275e-01, 2DIAGNOSTIC, 17, -7.912446856499e-01, 2.034957333308e-06, 5.1122e+00, 1.6637e-01, 2DIAGNOSTIC, 18, -7.912454009056e-01, 1.960850340765e-06, 5.2724e+00, 1.6017e-01, 2DIAGNOSTIC, 19, -7.912452220917e-01, 1.881354933175e-06, 5.4164e+00, 1.4403e-01, 2DIAGNOSTIC, 20, -7.912453413010e-01, 1.787427095223e-06, 5.5533e+00, 1.3682e-01, 2DIAGNOSTIC, 21, -7.912446260452e-01, 1.668239860919e-06, 5.6993e+00, 1.4607e-01, 2DIAGNOSTIC, 22, -7.912440299988e-01, 1.570598215039e-06, 5.8312e+00, 1.3183e-01, 2DIAGNOSTIC, 23, -7.912440896034e-01, 1.467342144679e-06, 5.9761e+00, 1.4497e-01, 2DIAGNOSTIC, 24, -7.912436127663e-01, 1.353643256152e-06, 6.1200e+00, 1.4390e-01, 2DIAGNOSTIC, 25, -7.912434339523e-01, 1.239436528522e-06, 6.2679e+00, 1.4791e-01, 2DIAGNOSTIC, 26, -7.912430763245e-01, 1.152445634034e-06, 6.3905e+00, 1.2259e-01, 2DIAGNOSTIC, 27, -7.912433147430e-01, 1.101477778320e-06, 6.5336e+00, 1.4306e-01, 2DIAGNOSTIC, 28, -7.912432551384e-01, 1.069586346603e-06, 6.6729e+00, 1.3928e-01, 2DIAGNOSTIC, 29, -7.912433147430e-01, 1.044516579896e-06, 6.7842e+00, 1.1132e-01, 2DIAGNOSTIC, 30, -7.912442684174e-01, 1.039178528117e-06, 6.9126e+00, 1.2846e-01, 2DIAGNOSTIC, 31, -7.912445664406e-01, 1.031217152558e-06, 7.0538e+00, 1.4119e-01, 2DIAGNOSTIC, 32, -7.912452220917e-01, 1.023840127345e-06, 7.1997e+00, 1.4584e-01, 2DIAGNOSTIC, 33, -7.912462949753e-01, 1.026476752486e-06, 7.3411e+00, 1.4141e-01, 2DIAGNOSTIC, 34, -7.912455201149e-01, 1.009611992231e-06, 7.4836e+00, 1.4255e-01, DIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 2DIAGNOSTIC, 1, -7.319419384003e-01, inf, 1.0104e+01, 2.6206e+00, 2DIAGNOSTIC, 2, -7.320255637169e-01, inf, 1.0866e+01, 7.6130e-01, 2DIAGNOSTIC, 3, -7.321835756302e-01, inf, 1.1720e+01, 8.5428e-01, 2DIAGNOSTIC, 4, -7.325546741486e-01, inf, 1.2823e+01, 1.1032e+00, 2DIAGNOSTIC, 5, -7.325605750084e-01, inf, 1.4128e+01, 1.3047e+00, 2DIAGNOSTIC, 6, -7.325593233109e-01, inf, 1.4998e+01, 8.7013e-01, 2DIAGNOSTIC, 7, -7.325590848923e-01, inf, 1.6615e+01, 1.6175e+00, 2DIAGNOSTIC, 8, -7.325595617294e-01, inf, 1.7588e+01, 9.7311e-01, 2DIAGNOSTIC, 9, -7.325595021248e-01, inf, 1.8452e+01, 8.6346e-01, 2DIAGNOSTIC, 10, -7.325592637062e-01, 5.555414463743e-05, 1.9307e+01, 8.5530e-01, 2DIAGNOSTIC, 11, -7.325592041016e-01, 3.339549948578e-05, 2.0154e+01, 8.4698e-01, 2DIAGNOSTIC, 12, -7.325591444969e-01, 1.489925671194e-05, 2.1023e+01, 8.6918e-01, 2DIAGNOSTIC, 13, -7.325589656830e-01, 2.537807176850e-06, 2.1886e+01, 8.6299e-01, 2DIAGNOSTIC, 14, -7.325589656830e-01, 2.214655751231e-06, 2.2767e+01, 8.8029e-01, 2DIAGNOSTIC, 15, -7.325590252876e-01, 2.095152694892e-06, 2.3629e+01, 8.6182e-01, 2DIAGNOSTIC, 16, -7.325590252876e-01, 1.962821670531e-06, 2.4493e+01, 8.6422e-01, 2DIAGNOSTIC, 17, -7.325589060783e-01, 1.839893684519e-06, 2.5483e+01, 9.9005e-01, 2DIAGNOSTIC, 18, -7.325588464737e-01, 1.742648919389e-06, 2.6324e+01, 8.4073e-01, 2DIAGNOSTIC, 19, -7.325587868690e-01, 1.655622554608e-06, 2.7183e+01, 8.5962e-01, 2DIAGNOSTIC, 20, -7.325587868690e-01, 1.574342832100e-06, 2.8061e+01, 8.7794e-01, 2DIAGNOSTIC, 21, -7.325587868690e-01, 1.501188421571e-06, 2.8922e+01, 8.6126e-01, 2DIAGNOSTIC, 22, -7.325587868690e-01, 1.435044623577e-06, 2.9801e+01, 8.7849e-01, 2DIAGNOSTIC, 23, -7.325588464737e-01, 1.373711370434e-06, 3.0646e+01, 8.4486e-01, 2DIAGNOSTIC, 24, -7.325587272644e-01, 1.316381940342e-06, 3.1492e+01, 8.4679e-01, 2DIAGNOSTIC, 25, -7.325587868690e-01, 1.266378262699e-06, 3.2359e+01, 8.6644e-01, 2DIAGNOSTIC, 26, -7.325587868690e-01, 1.220790863954e-06, 3.3220e+01, 8.6086e-01, 2DIAGNOSTIC, 27, -7.325586676598e-01, 1.175408328891e-06, 3.4107e+01, 8.8769e-01, 2DIAGNOSTIC, 28, -7.325586676598e-01, 1.132785087066e-06, 3.4970e+01, 8.6291e-01, 2DIAGNOSTIC, 29, -7.325588464737e-01, 1.095016159525e-06, 3.5804e+01, 8.3391e-01, 2DIAGNOSTIC, 30, -7.325588464737e-01, 1.059864416675e-06, 3.6685e+01, 8.8033e-01, 2DIAGNOSTIC, 31, -7.325587868690e-01, 1.026300310514e-06, 3.7556e+01, 8.7110e-01, DIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 2DIAGNOSTIC, 1, -6.547932624817e-01, inf, 4.4627e+01, 7.0709e+00, Elapsed time (stage 0): 4.7626e+01

Running AffineTransform registration

DIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 2DIAGNOSTIC, 1, -8.753327727318e-01, inf, 8.8499e-01, 8.8499e-01, 2DIAGNOSTIC, 2, -8.773011565208e-01, inf, 9.1909e-01, 3.4096e-02, 2DIAGNOSTIC, 3, -8.803265094757e-01, inf, 9.4889e-01, 2.9802e-02, 2DIAGNOSTIC, 4, -8.851005434990e-01, inf, 9.7814e-01, 2.9247e-02, 2DIAGNOSTIC, 5, -8.938973546028e-01, inf, 1.0126e+00, 3.4419e-02, 2DIAGNOSTIC, 6, -9.112679362297e-01, inf, 1.0467e+00, 3.4111e-02, 2DIAGNOSTIC, 7, -9.174267649651e-01, inf, 1.0772e+00, 3.0557e-02, 2DIAGNOSTIC, 8, -9.193696975708e-01, inf, 1.1153e+00, 3.8043e-02, 2DIAGNOSTIC, 9, -9.203177094460e-01, inf, 1.1584e+00, 4.3149e-02, 2DIAGNOSTIC, 10, -9.205778837204e-01, 4.051162861288e-03, 1.1885e+00, 3.0108e-02, 2DIAGNOSTIC, 11, -9.212089776993e-01, 3.345881123096e-03, 1.2182e+00, 2.9716e-02, 2DIAGNOSTIC, 12, -9.214870333672e-01, 2.518424764276e-03, 1.2509e+00, 3.2686e-02, 2DIAGNOSTIC, 13, -9.216032624245e-01, 1.674415660091e-03, 1.2838e+00, 3.2842e-02, 2DIAGNOSTIC, 14, -9.217308759689e-01, 9.121442562900e-04, 1.3220e+00, 3.8217e-02, 2DIAGNOSTIC, 15, -9.218672513962e-01, 3.483656910248e-04, 1.3606e+00, 3.8662e-02, 2DIAGNOSTIC, 16, -9.218725562096e-01, 1.613157946849e-04, 1.4034e+00, 4.2720e-02, 2DIAGNOSTIC, 17, -9.218752384186e-01, 9.444828174310e-05, 1.4421e+00, 3.8758e-02, 2DIAGNOSTIC, 18, -9.218798279762e-01, 6.010890501784e-05, 1.4889e+00, 4.6757e-02, 2DIAGNOSTIC, 19, -9.218777418137e-01, 3.959876994486e-05, 1.5263e+00, 3.7443e-02, 2DIAGNOSTIC, 20, -9.218764305115e-01, 2.144109748770e-05, 1.5594e+00, 3.3049e-02, 2DIAGNOSTIC, 21, -9.218710660934e-01, 1.240310939465e-05, 1.5988e+00, 3.9392e-02, 2DIAGNOSTIC, 22, -9.218695163727e-01, 7.104801170499e-06, 1.6381e+00, 3.9355e-02, 2DIAGNOSTIC, 23, -9.218684434891e-01, 3.276234565419e-06, 1.6764e+00, 3.8233e-02, 2DIAGNOSTIC, 24, -9.218629598618e-01, 1.128392000282e-06, 1.7103e+00, 3.3914e-02, DIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 2DIAGNOSTIC, 1, -8.258736133575e-01, inf, 2.7916e+00, 1.0814e+00, 2DIAGNOSTIC, 2, -8.267688155174e-01, inf, 2.9284e+00, 1.3678e-01, 2DIAGNOSTIC, 3, -8.275573849678e-01, inf, 3.0644e+00, 1.3597e-01, 2DIAGNOSTIC, 4, -8.283100128174e-01, inf, 3.2226e+00, 1.5821e-01, 2DIAGNOSTIC, 5, -8.290267586708e-01, inf, 3.3571e+00, 1.3450e-01, 2DIAGNOSTIC, 6, -8.294668793678e-01, inf, 3.5440e+00, 1.8693e-01, 2DIAGNOSTIC, 7, -8.295286297798e-01, inf, 3.7190e+00, 1.7503e-01, 2DIAGNOSTIC, 8, -8.295326232910e-01, inf, 3.8764e+00, 1.5733e-01, 2DIAGNOSTIC, 9, -8.295329213142e-01, inf, 4.0306e+00, 1.5423e-01, 2DIAGNOSTIC, 10, -8.295330405235e-01, 2.811318845488e-04, 4.1890e+00, 1.5838e-01, 2DIAGNOSTIC, 11, -8.295334577560e-01, 1.773726398824e-04, 4.3191e+00, 1.3011e-01, 2DIAGNOSTIC, 12, -8.295368552208e-01, 1.008333274513e-04, 4.4422e+00, 1.2308e-01, 2DIAGNOSTIC, 13, -8.295410871506e-01, 4.796810026164e-05, 4.5806e+00, 1.3846e-01, 2DIAGNOSTIC, 14, -8.295449614525e-01, 1.670620986260e-05, 4.7353e+00, 1.5467e-01, 2DIAGNOSTIC, 15, -8.295463323593e-01, 4.444212663657e-06, 4.8716e+00, 1.3633e-01, 2DIAGNOSTIC, 16, -8.295597434044e-01, 3.186740059391e-06, 5.0068e+00, 1.3517e-01, 2DIAGNOSTIC, 17, -8.295807242393e-01, 3.625807494245e-06, 5.1406e+00, 1.3379e-01, 2DIAGNOSTIC, 18, -8.296172022820e-01, 4.615103080141e-06, 5.2761e+00, 1.3554e-01, 2DIAGNOSTIC, 19, -8.296627998352e-01, 6.053637662262e-06, 5.4113e+00, 1.3520e-01, 2DIAGNOSTIC, 20, -8.297193646431e-01, 7.904136509751e-06, 5.5319e+00, 1.2054e-01, 2DIAGNOSTIC, 21, -8.298081159592e-01, 1.043316842697e-05, 5.8038e+00, 2.7189e-01, 2DIAGNOSTIC, 22, -8.298099040985e-01, 1.195372624352e-05, 6.0021e+00, 1.9833e-01, 2DIAGNOSTIC, 23, -8.298093676567e-01, 1.243188944500e-05, 6.1801e+00, 1.7801e-01, 2DIAGNOSTIC, 24, -8.298094272614e-01, 1.190261536976e-05, 6.3336e+00, 1.5348e-01, 2DIAGNOSTIC, 25, -8.298096060753e-01, 1.043048541760e-05, 6.4888e+00, 1.5522e-01, 2DIAGNOSTIC, 26, -8.298087716103e-01, 8.361105756194e-06, 6.6696e+00, 1.8082e-01, 2DIAGNOSTIC, 27, -8.298089504242e-01, 6.042660061212e-06, 6.9054e+00, 2.3580e-01, 2DIAGNOSTIC, 28, -8.298090696335e-01, 3.889076651831e-06, 7.0609e+00, 1.5543e-01, 2DIAGNOSTIC, 29, -8.298089504242e-01, 2.155290758310e-06, 7.2192e+00, 1.5831e-01, 2DIAGNOSTIC, 30, -8.298085331917e-01, 1.049720140145e-06, 7.3707e+00, 1.5155e-01, DIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 2DIAGNOSTIC, 1, -7.666717171669e-01, inf, 1.0064e+01, 2.6932e+00, 2DIAGNOSTIC, 2, -7.669141888618e-01, inf, 1.0898e+01, 8.3404e-01, 2DIAGNOSTIC, 3, -7.670834064484e-01, inf, 1.1744e+01, 8.4639e-01, 2DIAGNOSTIC, 4, -7.673202753067e-01, inf, 1.2596e+01, 8.5177e-01, 2DIAGNOSTIC, 5, -7.674955129623e-01, inf, 1.3748e+01, 1.1520e+00, 2DIAGNOSTIC, 6, -7.674977779388e-01, inf, 1.4571e+01, 8.2289e-01, 2DIAGNOSTIC, 7, -7.675192952156e-01, inf, 1.5423e+01, 8.5146e-01, 2DIAGNOSTIC, 8, -7.675562500954e-01, inf, 1.6246e+01, 8.2381e-01, 2DIAGNOSTIC, 9, -7.675827741623e-01, inf, 1.7099e+01, 8.5288e-01, 2DIAGNOSTIC, 10, -7.676434516907e-01, 7.655876834178e-05, 1.8802e+01, 1.7030e+00, 2DIAGNOSTIC, 11, -7.676427364349e-01, 5.117627733853e-05, 1.9859e+01, 1.0566e+00, 2DIAGNOSTIC, 12, -7.676427960396e-01, 3.322925113025e-05, 2.1152e+01, 1.2928e+00, 2DIAGNOSTIC, 13, -7.676430940628e-01, 1.998535299208e-05, 2.2095e+01, 9.4314e-01, 2DIAGNOSTIC, 14, -7.676430940628e-01, 1.316205998592e-05, 2.3038e+01, 9.4376e-01, 2DIAGNOSTIC, 15, -7.676428556442e-01, 1.056742166838e-05, 2.3999e+01, 9.6049e-01, 2DIAGNOSTIC, 16, -7.676431536674e-01, 7.583308615722e-06, 2.5059e+01, 1.0600e+00, 2DIAGNOSTIC, 17, -7.676429152489e-01, 4.904046363663e-06, 2.6029e+01, 9.6988e-01, 2DIAGNOSTIC, 18, -7.676428556442e-01, 3.000664719366e-06, 2.7113e+01, 1.0846e+00, 2DIAGNOSTIC, 19, -7.676424980164e-01, 1.659415715949e-06, 2.8182e+01, 1.0682e+00, 2DIAGNOSTIC, 20, -7.676424980164e-01, 1.577854277457e-06, 2.9237e+01, 1.0554e+00, 2DIAGNOSTIC, 21, -7.676424980164e-01, 1.492540604886e-06, 3.0205e+01, 9.6779e-01, 2DIAGNOSTIC, 22, -7.676424980164e-01, 1.417834482709e-06, 3.1156e+01, 9.5101e-01, 2DIAGNOSTIC, 23, -7.676424980164e-01, 1.357159703730e-06, 3.2108e+01, 9.5194e-01, 2DIAGNOSTIC, 24, -7.676424980164e-01, 1.304188572249e-06, 3.3074e+01, 9.6673e-01, 2DIAGNOSTIC, 25, -7.676424980164e-01, 1.253774939869e-06, 3.4045e+01, 9.7075e-01, 2DIAGNOSTIC, 26, -7.676426172256e-01, 1.214957251250e-06, 3.4996e+01, 9.5049e-01, 2DIAGNOSTIC, 27, -7.676424980164e-01, 1.174847056973e-06, 3.5960e+01, 9.6481e-01, 2DIAGNOSTIC, 28, -7.676424384117e-01, 1.136553578363e-06, 3.7009e+01, 1.0484e+00, 2DIAGNOSTIC, 29, -7.676424980164e-01, 1.097094013858e-06, 3.7951e+01, 9.4189e-01, 2DIAGNOSTIC, 30, -7.676424980164e-01, 1.060201725522e-06, 3.8917e+01, 9.6606e-01, 2DIAGNOSTIC, 31, -7.676424384117e-01, 1.024982225317e-06, 3.9864e+01, 9.4703e-01, DIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 2DIAGNOSTIC, 1, -6.857931017876e-01, inf, 4.6807e+01, 6.9435e+00, Elapsed time (stage 1): 4.9771e+01

Running SyN registration (varianceForUpdateField = 3.0000e+00, varianceForTotalField = 0.0000e+00)

XXDIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 1DIAGNOSTIC, 1, -8.390960693359e-01, inf, 2.1913e+00, 2.1913e+00, 1DIAGNOSTIC, 2, -8.467877507210e-01, inf, 3.6940e+00, 1.5027e+00, 1DIAGNOSTIC, 3, -8.540546298027e-01, inf, 5.1882e+00, 1.4942e+00, 1DIAGNOSTIC, 4, -8.603593111038e-01, inf, 6.6926e+00, 1.5044e+00, 1DIAGNOSTIC, 5, -8.662253618240e-01, inf, 8.1953e+00, 1.5027e+00, 1DIAGNOSTIC, 6, -8.709731698036e-01, inf, 9.6748e+00, 1.4796e+00, 1DIAGNOSTIC, 7, -8.752954602242e-01, inf, 1.1173e+01, 1.4979e+00, 1DIAGNOSTIC, 8, -8.791313171387e-01, inf, 1.2673e+01, 1.5008e+00, 1DIAGNOSTIC, 9, -8.826911449432e-01, inf, 1.4172e+01, 1.4985e+00, 1DIAGNOSTIC, 10, -8.859126567841e-01, 3.401219379157e-03, 1.5699e+01, 1.5274e+00, 1DIAGNOSTIC, 11, -8.888351917267e-01, 2.749880077317e-03, 1.7229e+01, 1.5294e+00, 1DIAGNOSTIC, 12, -8.913473486900e-01, 2.237439155579e-03, 1.8755e+01, 1.5266e+00, 1DIAGNOSTIC, 13, -8.936166763306e-01, 1.840227399953e-03, 2.0269e+01, 1.5133e+00, 1DIAGNOSTIC, 14, -8.956779837608e-01, 1.525988103822e-03, 2.1799e+01, 1.5302e+00, 1DIAGNOSTIC, 15, -8.975560665131e-01, 1.281298580579e-03, 2.3290e+01, 1.4910e+00, 1DIAGNOSTIC, 16, -8.992738127708e-01, 1.080033136532e-03, 2.4798e+01, 1.5086e+00, 1DIAGNOSTIC, 17, -9.008507132530e-01, 9.148367680609e-04, 2.6302e+01, 1.5039e+00, 1DIAGNOSTIC, 18, -9.023038148880e-01, 7.779577281326e-04, 2.7805e+01, 1.5023e+00, 1DIAGNOSTIC, 19, -9.036461114883e-01, 6.661899969913e-04, 2.9298e+01, 1.4930e+00, 1DIAGNOSTIC, 20, -9.048860669136e-01, 5.751329590566e-04, 3.0859e+01, 1.5609e+00, 1DIAGNOSTIC, 21, -9.060373306274e-01, 5.012635956518e-04, 3.2362e+01, 1.5031e+00, 1DIAGNOSTIC, 22, -9.071102142334e-01, 4.393865820020e-04, 3.3858e+01, 1.4961e+00, 1DIAGNOSTIC, 23, -9.081087112427e-01, 3.871317312587e-04, 3.5358e+01, 1.5005e+00, 1DIAGNOSTIC, 24, -9.090401530266e-01, 3.427037154324e-04, 3.6881e+01, 1.5232e+00, 1DIAGNOSTIC, 25, -9.099112749100e-01, 3.046810161322e-04, 3.8404e+01, 1.5222e+00, 1DIAGNOSTIC, 26, -9.107281565666e-01, 2.719538751990e-04, 3.9920e+01, 1.5162e+00, 1DIAGNOSTIC, 27, -9.114946722984e-01, 2.436342329020e-04, 4.1446e+01, 1.5258e+00, 1DIAGNOSTIC, 28, -9.122154712677e-01, 2.190269879065e-04, 4.2914e+01, 1.4688e+00, 1DIAGNOSTIC, 29, -9.128953218460e-01, 1.975738414330e-04, 4.4413e+01, 1.4985e+00, 1DIAGNOSTIC, 30, -9.135379791260e-01, 1.787835935829e-04, 4.5915e+01, 1.5020e+00, 1DIAGNOSTIC, 31, -9.141452312469e-01, 1.622718846193e-04, 4.7418e+01, 1.5035e+00, 1DIAGNOSTIC, 32, -9.147188663483e-01, 1.477254554629e-04, 4.8938e+01, 1.5196e+00, 1DIAGNOSTIC, 33, -9.152631759644e-01, 1.348620280623e-04, 5.0437e+01, 1.4996e+00, 1DIAGNOSTIC, 34, -9.157803654671e-01, 1.234456867678e-04, 5.1910e+01, 1.4728e+00, 1DIAGNOSTIC, 35, -9.162704944611e-01, 1.132644392783e-04, 5.3399e+01, 1.4884e+00, 1DIAGNOSTIC, 36, -9.167395830154e-01, 1.041833893396e-04, 5.4918e+01, 1.5196e+00, 1DIAGNOSTIC, 37, -9.171836376190e-01, 9.602995851310e-05, 5.6416e+01, 1.4974e+00, 1DIAGNOSTIC, 38, -9.176080226898e-01, 8.869329030858e-05, 5.7925e+01, 1.5090e+00, 1DIAGNOSTIC, 39, -9.180146455765e-01, 8.209048974095e-05, 5.9445e+01, 1.5207e+00, 1DIAGNOSTIC, 40, -9.184039831161e-01, 7.614682544954e-05, 6.0980e+01, 1.5343e+00, 1DIAGNOSTIC, 41, -9.187743663788e-01, 7.076553447405e-05, 6.2492e+01, 1.5124e+00, 1DIAGNOSTIC, 42, -9.191299676895e-01, 6.587873212993e-05, 6.3994e+01, 1.5023e+00, 1DIAGNOSTIC, 43, -9.194713830948e-01, 6.143734208308e-05, 6.5479e+01, 1.4849e+00, 1DIAGNOSTIC, 44, -9.197991490364e-01, 5.739576226915e-05, 6.6976e+01, 1.4964e+00, 1DIAGNOSTIC, 45, -9.201134443283e-01, 5.369507925934e-05, 6.8473e+01, 1.4976e+00, 1DIAGNOSTIC, 46, -9.204171895981e-01, 5.032944318373e-05, 6.9990e+01, 1.5166e+00, 1DIAGNOSTIC, 47, -9.207082986832e-01, 4.723454912892e-05, 7.1484e+01, 1.4940e+00, 1DIAGNOSTIC, 48, -9.209889769554e-01, 4.438930409378e-05, 7.3009e+01, 1.5248e+00, 1DIAGNOSTIC, 49, -9.212602376938e-01, 4.178171002422e-05, 7.4526e+01, 1.5171e+00, 1DIAGNOSTIC, 50, -9.215211868286e-01, 3.938701411244e-05, 7.6035e+01, 1.5096e+00, 1DIAGNOSTIC, 51, -9.217747449875e-01, 3.717951767612e-05, 7.7520e+01, 1.4848e+00, 1DIAGNOSTIC, 52, -9.220181703568e-01, 3.513497722452e-05, 7.9026e+01, 1.5060e+00, 1DIAGNOSTIC, 53, -9.222540855408e-01, 3.324338467792e-05, 8.0547e+01, 1.5210e+00, 1DIAGNOSTIC, 54, -9.224809408188e-01, 3.148194809910e-05, 8.2026e+01, 1.4791e+00, 1DIAGNOSTIC, 55, -9.227009415627e-01, 2.983730155393e-05, 8.3520e+01, 1.4936e+00, 1DIAGNOSTIC, 56, -9.229137897491e-01, 2.830697485479e-05, 8.5058e+01, 1.5381e+00, 1DIAGNOSTIC, 57, -9.231197834015e-01, 2.687341475394e-05, 8.6560e+01, 1.5021e+00, 1DIAGNOSTIC, 58, -9.233186841011e-01, 2.552692239988e-05, 8.8037e+01, 1.4766e+00, 1DIAGNOSTIC, 59, -9.235112667084e-01, 2.426460923743e-05, 8.9556e+01, 1.5188e+00, 1DIAGNOSTIC, 60, -9.236993789673e-01, 2.308448893018e-05, 9.1068e+01, 1.5122e+00, 1DIAGNOSTIC, 61, -9.238809943199e-01, 2.198568836320e-05, 9.2533e+01, 1.4651e+00, 1DIAGNOSTIC, 62, -9.240563511848e-01, 2.095085983456e-05, 9.4004e+01, 1.4710e+00, 1DIAGNOSTIC, 63, -9.242281913757e-01, 1.998810148507e-05, 9.5490e+01, 1.4857e+00, 1DIAGNOSTIC, 64, -9.243942499161e-01, 1.908167178044e-05, 9.6985e+01, 1.4953e+00, 1DIAGNOSTIC, 65, -9.245548248291e-01, 1.822680496844e-05, 9.8518e+01, 1.5332e+00, 1DIAGNOSTIC, 66, -9.247093200684e-01, 1.741272535583e-05, 1.0000e+02, 1.4842e+00, 1DIAGNOSTIC, 67, -9.248608350754e-01, 1.664391311351e-05, 1.0149e+02, 1.4906e+00, 1DIAGNOSTIC, 68, -9.250057935715e-01, 1.590428473719e-05, 1.0301e+02, 1.5176e+00, 1DIAGNOSTIC, 69, -9.251471757889e-01, 1.519551915408e-05, 1.0451e+02, 1.5026e+00, 1DIAGNOSTIC, 70, -9.252834916115e-01, 1.452007381886e-05, 1.0602e+02, 1.5024e+00, 1DIAGNOSTIC, 71, -9.254161119461e-01, 1.387617976434e-05, 1.0753e+02, 1.5115e+00, 1DIAGNOSTIC, 72, -9.255453944206e-01, 1.326294204773e-05, 1.0902e+02, 1.4967e+00, 1DIAGNOSTIC, 73, -9.256705045700e-01, 1.268681808142e-05, 1.1051e+02, 1.4898e+00, 1DIAGNOSTIC, 74, -9.257921576500e-01, 1.214566054841e-05, 1.1202e+02, 1.5108e+00, 1DIAGNOSTIC, 75, -9.259098768234e-01, 1.163476099464e-05, 1.1355e+02, 1.5255e+00, 1DIAGNOSTIC, 76, -9.260246753693e-01, 1.114949191106e-05, 1.1504e+02, 1.4890e+00, 1DIAGNOSTIC, 77, -9.261361956596e-01, 1.069577228918e-05, 1.1655e+02, 1.5134e+00, 1DIAGNOSTIC, 78, -9.262436628342e-01, 1.025975780067e-05, 1.1803e+02, 1.4738e+00, 1DIAGNOSTIC, 79, -9.263494610786e-01, 9.849313755694e-06, 1.1956e+02, 1.5313e+00, 1DIAGNOSTIC, 80, -9.264529347420e-01, 9.461638001085e-06, 1.2105e+02, 1.4887e+00, 1DIAGNOSTIC, 81, -9.265527725220e-01, 9.093153494177e-06, 1.2255e+02, 1.5037e+00, 1DIAGNOSTIC, 82, -9.266495704651e-01, 8.743549187784e-06, 1.2409e+02, 1.5433e+00, 1DIAGNOSTIC, 83, -9.267435669899e-01, 8.409167094214e-06, 1.2558e+02, 1.4893e+00, 1DIAGNOSTIC, 84, -9.268354773521e-01, 8.091059498838e-06, 1.2710e+02, 1.5196e+00, 1DIAGNOSTIC, 85, -9.269246459007e-01, 7.785112757119e-06, 1.2860e+02, 1.4949e+00, 1DIAGNOSTIC, 86, -9.270119667053e-01, 7.494216788473e-06, 1.3007e+02, 1.4767e+00, 1DIAGNOSTIC, 87, -9.270973205566e-01, 7.218707651191e-06, 1.3156e+02, 1.4831e+00, 1DIAGNOSTIC, 88, -9.271790981293e-01, 6.949266662559e-06, 1.3308e+02, 1.5223e+00, 1DIAGNOSTIC, 89, -9.272602200508e-01, 6.695814136037e-06, 1.3458e+02, 1.5048e+00, 1DIAGNOSTIC, 90, -9.273386597633e-01, 6.457409199356e-06, 1.3609e+02, 1.5103e+00, 1DIAGNOSTIC, 91, -9.274144172668e-01, 6.227941412362e-06, 1.3761e+02, 1.5201e+00, 1DIAGNOSTIC, 92, -9.274880886078e-01, 6.005319846736e-06, 1.3912e+02, 1.5071e+00, 1DIAGNOSTIC, 93, -9.275595545769e-01, 5.787611826236e-06, 1.4062e+02, 1.4981e+00, 1DIAGNOSTIC, 94, -9.276288747787e-01, 5.575539489655e-06, 1.4212e+02, 1.4996e+00, 1DIAGNOSTIC, 95, -9.276963472366e-01, 5.368453003030e-06, 1.4364e+02, 1.5211e+00, 1DIAGNOSTIC, 96, -9.277622103691e-01, 5.169446467335e-06, 1.4514e+02, 1.4997e+00, 1DIAGNOSTIC, 97, -9.278267621994e-01, 4.981815891369e-06, 1.4667e+02, 1.5266e+00, 1DIAGNOSTIC, 98, -9.278891086578e-01, 4.799729140359e-06, 1.4818e+02, 1.5178e+00, 1DIAGNOSTIC, 99, -9.279505610466e-01, 4.631038791558e-06, 1.4972e+02, 1.5312e+00, 1DIAGNOSTIC, 100, -9.280096888542e-01, 4.471455667954e-06, 1.5127e+02, 1.5496e+00, XXDIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 1DIAGNOSTIC, 1, -8.836729526520e-01, inf, 1.5863e+02, 7.3629e+00, 1DIAGNOSTIC, 2, -8.855416774750e-01, inf, 1.6501e+02, 6.3847e+00, 1DIAGNOSTIC, 3, -8.875142335892e-01, inf, 1.7150e+02, 6.4860e+00, 1DIAGNOSTIC, 4, -8.893364071846e-01, inf, 1.7780e+02, 6.3058e+00, 1DIAGNOSTIC, 5, -8.909915089607e-01, inf, 1.8432e+02, 6.5131e+00, 1DIAGNOSTIC, 6, -8.924906849861e-01, inf, 1.9072e+02, 6.4041e+00, 1DIAGNOSTIC, 7, -8.938497304916e-01, inf, 1.9716e+02, 6.4391e+00, 1DIAGNOSTIC, 8, -8.950742483139e-01, inf, 2.0365e+02, 6.4845e+00, 1DIAGNOSTIC, 9, -8.960127830505e-01, inf, 2.1021e+02, 6.5599e+00, 1DIAGNOSTIC, 10, -8.969411849976e-01, 9.624703088775e-04, 2.1660e+02, 6.3936e+00, 1DIAGNOSTIC, 11, -8.977087140083e-01, 7.915846072137e-04, 2.2311e+02, 6.5064e+00, 1DIAGNOSTIC, 12, -8.984084129333e-01, 6.458511343226e-04, 2.2960e+02, 6.4985e+00, 1DIAGNOSTIC, 13, -8.990522623062e-01, 5.278753815219e-04, 2.3605e+02, 6.4443e+00, 1DIAGNOSTIC, 14, -8.996432423592e-01, 4.333349643275e-04, 2.4265e+02, 6.6000e+00, 1DIAGNOSTIC, 15, -9.001889228821e-01, 3.582313365769e-04, 2.4920e+02, 6.5475e+00, 1DIAGNOSTIC, 16, -9.006943702698e-01, 2.992351655848e-04, 2.5574e+02, 6.5429e+00, 1DIAGNOSTIC, 17, -9.011620283127e-01, 2.535562671255e-04, 2.6241e+02, 6.6749e+00, 1DIAGNOSTIC, 18, -9.015952348709e-01, 2.186823548982e-04, 2.6882e+02, 6.4068e+00, 1DIAGNOSTIC, 19, -9.019976258278e-01, 1.894950110000e-04, 2.7527e+02, 6.4527e+00, 1DIAGNOSTIC, 20, -9.023742675781e-01, 1.662634749664e-04, 2.8179e+02, 6.5172e+00, 1DIAGNOSTIC, 21, -9.027239680290e-01, 1.465885870857e-04, 2.8839e+02, 6.6005e+00, 1DIAGNOSTIC, 22, -9.030517339706e-01, 1.297972485190e-04, 2.9480e+02, 6.4133e+00, 1DIAGNOSTIC, 23, -9.033558964729e-01, 1.153736375272e-04, 3.0136e+02, 6.5533e+00, 1DIAGNOSTIC, 24, -9.036432504654e-01, 1.029314516927e-04, 3.0777e+02, 6.4115e+00, 1DIAGNOSTIC, 25, -9.039118885994e-01, 9.214201418217e-05, 3.1419e+02, 6.4259e+00, 1DIAGNOSTIC, 26, -9.041651487350e-01, 8.277001325041e-05, 3.2076e+02, 6.5640e+00, 1DIAGNOSTIC, 27, -9.044055938721e-01, 7.461835775757e-05, 3.2723e+02, 6.4751e+00, 1DIAGNOSTIC, 28, -9.046285152435e-01, 6.745191058144e-05, 3.3371e+02, 6.4803e+00, 1DIAGNOSTIC, 29, -9.048345685005e-01, 6.107769877417e-05, 3.4029e+02, 6.5711e+00, 1DIAGNOSTIC, 30, -9.050258398056e-01, 5.537640754483e-05, 3.4670e+02, 6.4114e+00, 1DIAGNOSTIC, 31, -9.052031636238e-01, 5.021485776524e-05, 3.5310e+02, 6.4071e+00, 1DIAGNOSTIC, 32, -9.053676128387e-01, 4.552133395919e-05, 3.5961e+02, 6.5015e+00, 1DIAGNOSTIC, 33, -9.055213332176e-01, 4.122300379095e-05, 3.6600e+02, 6.3961e+00, 1DIAGNOSTIC, 34, -9.056652188301e-01, 3.731770993909e-05, 3.7238e+02, 6.3786e+00, 1DIAGNOSTIC, 35, -9.058000445366e-01, 3.377865141374e-05, 3.7900e+02, 6.6204e+00, 1DIAGNOSTIC, 36, -9.059253931046e-01, 3.059309165110e-05, 3.8537e+02, 6.3668e+00, 1DIAGNOSTIC, 37, -9.060450792313e-01, 2.779086389637e-05, 3.9183e+02, 6.4639e+00, 1DIAGNOSTIC, 38, -9.061548709869e-01, 2.530329402362e-05, 3.9832e+02, 6.4858e+00, 1DIAGNOSTIC, 39, -9.062585830688e-01, 2.308995135536e-05, 4.0482e+02, 6.5007e+00, 1DIAGNOSTIC, 40, -9.063557386398e-01, 2.111256617354e-05, 4.1120e+02, 6.3855e+00, 1DIAGNOSTIC, 41, -9.064475893974e-01, 1.934070496645e-05, 4.1768e+02, 6.4735e+00, 1DIAGNOSTIC, 42, -9.065347909927e-01, 1.774899828888e-05, 4.2415e+02, 6.4741e+00, 1DIAGNOSTIC, 43, -9.066162109375e-01, 1.631284249015e-05, 4.3065e+02, 6.5030e+00, 1DIAGNOSTIC, 44, -9.066926240921e-01, 1.501444876340e-05, 4.3708e+02, 6.4220e+00, 1DIAGNOSTIC, 45, -9.067650437355e-01, 1.384292681905e-05, 4.4347e+02, 6.3934e+00, 1DIAGNOSTIC, 46, -9.068349003792e-01, 1.278761283174e-05, 4.5001e+02, 6.5458e+00, 1DIAGNOSTIC, 47, -9.069001674652e-01, 1.184542088595e-05, 4.5657e+02, 6.5505e+00, 1DIAGNOSTIC, 48, -9.069613814354e-01, 1.098280790757e-05, 4.6296e+02, 6.3946e+00, 1DIAGNOSTIC, 49, -9.070208072662e-01, 1.020432591758e-05, 4.6951e+02, 6.5547e+00, 1DIAGNOSTIC, 50, -9.070777893066e-01, 9.501321073913e-06, 4.7608e+02, 6.5664e+00, 1DIAGNOSTIC, 51, -9.071314334869e-01, 8.863888069754e-06, 4.8251e+02, 6.4298e+00, 1DIAGNOSTIC, 52, -9.071818590164e-01, 8.284800060210e-06, 4.8896e+02, 6.4523e+00, 1DIAGNOSTIC, 53, -9.072289466858e-01, 7.746572919132e-06, 4.9540e+02, 6.4338e+00, 1DIAGNOSTIC, 54, -9.072759151459e-01, 7.253975581989e-06, 5.0179e+02, 6.3910e+00, 1DIAGNOSTIC, 55, -9.073193073273e-01, 6.794156888645e-06, 5.0829e+02, 6.4983e+00, 1DIAGNOSTIC, 56, -9.073607921600e-01, 6.372634743457e-06, 5.1475e+02, 6.4636e+00, 1DIAGNOSTIC, 57, -9.074009060860e-01, 5.984022664052e-06, 5.2132e+02, 6.5708e+00, 1DIAGNOSTIC, 58, -9.074397087097e-01, 5.623996457871e-06, 5.2775e+02, 6.4299e+00, 1DIAGNOSTIC, 59, -9.074761867523e-01, 5.293762114889e-06, 5.3426e+02, 6.5120e+00, 1DIAGNOSTIC, 60, -9.075114727020e-01, 4.995803465135e-06, 5.4065e+02, 6.3884e+00, 1DIAGNOSTIC, 61, -9.075450897217e-01, 4.723255642602e-06, 5.4718e+02, 6.5292e+00, 1DIAGNOSTIC, 62, -9.075775146484e-01, 4.471129159356e-06, 5.5359e+02, 6.4099e+00, 1DIAGNOSTIC, 63, -9.076080322266e-01, 4.228934358252e-06, 5.6018e+02, 6.5909e+00, 1DIAGNOSTIC, 64, -9.076373577118e-01, 4.006789367850e-06, 5.6654e+02, 6.3604e+00, 1DIAGNOSTIC, 65, -9.076660871506e-01, 3.798768830165e-06, 5.7310e+02, 6.5583e+00, 1DIAGNOSTIC, 66, -9.076930284500e-01, 3.600648824431e-06, 5.7949e+02, 6.3856e+00, 1DIAGNOSTIC, 67, -9.077185392380e-01, 3.412568048589e-06, 5.8594e+02, 6.4568e+00, 1DIAGNOSTIC, 68, -9.077439904213e-01, 3.241009835619e-06, 5.9234e+02, 6.3946e+00, 1DIAGNOSTIC, 69, -9.077687263489e-01, 3.082971943513e-06, 5.9880e+02, 6.4611e+00, 1DIAGNOSTIC, 70, -9.077920913696e-01, 2.937129238489e-06, 6.0525e+02, 6.4522e+00, 1DIAGNOSTIC, 71, 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-8.536323904991e-01, 8.506447557011e-06, 4.4022e+03, 5.2911e+01, 1DIAGNOSTIC, 69, -8.537016510963e-01, 8.143506420311e-06, 4.4548e+03, 5.2542e+01, 1DIAGNOSTIC, 70, -8.537696003914e-01, 7.803989319655e-06, 4.5078e+03, 5.3089e+01, XXDIAGNOSTIC,Iteration,metricValue,convergenceValue,ITERATION_TIME_INDEX,SINCE_LAST 1DIAGNOSTIC, 1, -7.427430152893e-01, inf, 4.7180e+03, 2.1018e+02, 1DIAGNOSTIC, 2, -7.423723340034e-01, inf, 4.9243e+03, 2.0632e+02, 1DIAGNOSTIC, 3, -7.422466874123e-01, inf, 5.1347e+03, 2.1039e+02, 1DIAGNOSTIC, 4, -7.421209812164e-01, inf, 5.3427e+03, 2.0795e+02, 1DIAGNOSTIC, 5, -7.419930100441e-01, inf, 5.5493e+03, 2.0657e+02, 1DIAGNOSTIC, 6, -7.418628931046e-01, inf, 5.7583e+03, 2.0904e+02, 1DIAGNOSTIC, 7, -7.417315840721e-01, inf, 5.9632e+03, 2.0488e+02, 1DIAGNOSTIC, 8, -7.416137456894e-01, inf, 6.1685e+03, 2.0527e+02, 1DIAGNOSTIC, 9, -7.415322065353e-01, inf, 6.3770e+03, 2.0853e+02, 1DIAGNOSTIC, 10, -7.414509057999e-01, -9.923643665388e-05, 6.5853e+03, 2.0834e+02, Elapsed time (stage 2): 6591

Total elapsed time: 6688 Using single precision for computations. Input scalar image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template02000013Repaired.nii.gz Reference image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz

The composite transform comprises the following transforms (in order):

/media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200001340GenericAffine.mat (type = AffineTransform)
/media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200001341Warp.nii.gz (type = DisplacementFieldTransform)

Default pixel value: 0 Interpolation type: LinearInterpolateImageFunction Output warped image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template020000134WarpedToTemplate.nii.gz shapeupdatetotemplate()

shapeupdatetotemplate---voxel-wise averaging of the warped images to the current template

1. 1. (금) 14:11:16 KST
    
    bigimage 4 maxSize [244, 512, 512] Setting physical space of output average image based on largest image Averaging 5 images with dim = 3 vector components 1 reading /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template020000010WarpedToTemplate.nii.gz reading /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template020000021WarpedToTemplate.nii.gz reading /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template020000052WarpedToTemplate.nii.gz reading /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template020000083WarpedToTemplate.nii.gz reading /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template020000134WarpedToTemplate.nii.gz writing output Laplacian sharpening number of warps = 5 /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000101Warp.nii.gz 5 does not equal 0

shapeupdatetotemplate---voxel-wise averaging of the inverse warp fields (from subject to template) /usr/local/ANTs/bin/AverageImages 3 /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0warp.nii.gz 0 /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000101Warp.nii.gz /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000211Warp.nii.gz /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000521Warp.nii.gz /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000831Warp.nii.gz /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200001341Warp.nii.gz

1. 1. (금) 14:11:40 KST
    
    fn /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000101Warp.nii.gz 3 3 bigimage 4 size [244, 512, 512] bigimage 4 size [244, 512, 512] bigimage 4 size [244, 512, 512] fn /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000211Warp.nii.gz 3 3 fn /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000521Warp.nii.gz 3 3 fn /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000831Warp.nii.gz 3 3 fn /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200001341Warp.nii.gz 3 3 largest image [244, 512, 512] Averaging 5 images with dim = 3 vector components 3 reading /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000101Warp.nii.gz for average reading /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000211Warp.nii.gz for average reading /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000521Warp.nii.gz for average reading /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000831Warp.nii.gz for average reading /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200001341Warp.nii.gz for average

shapeupdatetotemplate---scale the averaged inverse warp field by the gradient step /usr/local/ANTs/bin/MultiplyImages 3 /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0warp.nii.gz -0.15 /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0warp.nii.gz

1. 1. (금) 14:12:39 KST

shapeupdatetotemplate---average the affine transforms (template <-> subject) ---transform the inverse field by the resulting average affine transform /usr/local/ANTs/bin/AverageAffineTransform 3 /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0GenericAffine.mat /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_testT*GenericAffine.mat /usr/local/ANTs/bin/antsApplyTransforms -d 3 -e vector -i /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0warp.nii.gz -o /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0warp.nii.gz -t [ /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0GenericAffine.mat,1 ] -r /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz --verbose 1

output_transform_filename: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0GenericAffine.mat reference_transform_filename: NULL [0/5]: AFFINE: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000100GenericAffine.mat [1/5]: AFFINE: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000210GenericAffine.mat [2/5]: AFFINE: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000520GenericAffine.mat [3/5]: AFFINE: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000830GenericAffine.mat [4/5]: AFFINE: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200001340GenericAffine.mat the reference affine file for center is selected as the first affine! new center is : [0.389297, -10.8862, -1.06683] A=0.989959 0.0914858 -0.0104515 -0.0391609 0.99326 -0.0527316 -0.00533412 0.0218811 1.0176

rotation R0.999204 0.0396371 0.0044992 -0.0395266 0.998967 -0.0224382 -0.00538393 0.0222425 0.999738

upper R0.990748 0.052035 -0.0138375 0 0.996347 -0.0304574 0 0 1.01847

s=0.250065 u=0.0111731 v=0.00247143 w-0.0197961 r=0.999739 m_Rotation from vnl0.0111731 0.00247143 -0.0197961 0.999739 internal_transform: ANTSAffine3DTransform (0x55d29cf59ca0) RTTI typeinfo: itk::ANTSAffine3DTransform Reference Count: 3 Modified Time: 627 Debug: Off Object Name: Observers: none Matrix: 0.989959 0.0914858 -0.0104515 -0.0391609 0.99326 -0.0527316 -0.00533412 0.0218811 1.0176 Offset: [-4.21046, -0.951079, 18.1318] Center: [0.389297, -10.8862, -1.06683] Translation: [-5.19915, -0.836696, 17.8728] Inverse: 1.0065 -0.0928271 0.00552722 0.0399175 1.00196 0.052331 0.00441761 -0.0220313 0.98161 Singular: 0 Rotation: 0.0111731 0.00247143 -0.0197961 0.999739 S1, S2, S3: 0.990748, 0.996347, 1.01847 K1, K2, K3: 0.0525209, -0.0139667, -0.0305691

A=1.01825 -0.0378265 0.0263633 0.0198813 0.989096 -0.0169953 -0.0328201 0.0556832 1.01389

rotation R0.999291 -0.0177023 0.0332375 0.0195111 0.998301 -0.0549099 -0.032209 0.0555194 0.997938

upper R1.01897 -0.0202948 -0.00664328 0 0.991176 0.0388572 0 0 1.0136

s=0.25014 u=0.0276228 v=0.0163708 w0.00930857 r=0.999441 m_Rotation from vnl0.0276228 0.0163708 0.00930857 0.999441 internal_transform: ANTSAffine3DTransform (0x55d29cf5a2b0) RTTI typeinfo: itk::ANTSAffine3DTransform Reference Count: 3 Modified Time: 634 Debug: Off Object Name: Observers: none Matrix: 1.01825 -0.0378265 0.0263633 0.0198813 0.989096 -0.0169953 -0.0328201 0.0556832 1.01389 Offset: [2.69241, 0.895086, -7.00447] Center: [0.389297, -10.8862, -1.06683] Translation: [3.08318, 1.03966, -7.63824] Inverse: 0.980517 0.038897 -0.0248436 -0.0191454 1.00931 0.0174165 0.0327914 -0.0541728 0.984543 Singular: 0 Rotation: 0.0276228 0.0163708 0.00930857 0.999441 S1, S2, S3: 1.01897, 0.991176, 1.0136 K1, K2, K3: -0.0199169, -0.00651959, 0.0392031

A=1.00704 -0.0474359 -0.0300319 -0.00426216 0.963137 0.00107288 0.038729 -0.0137559 0.974968

rotation R0.999252 0.00470154 -0.0383745 -0.00422919 0.999914 0.0123808 0.0384294 -0.0122092 0.999187

upper R1.0078 -0.0520023 0.00745342 0 0.963 -0.010972 0 0 0.97534

s=0.250051 u=-0.00614875 v=-0.0192049 w-0.00223314 r=0.999794 m_Rotation from vnl-0.00614875 -0.0192049 -0.00223314 0.999794 internal_transform: ANTSAffine3DTransform (0x55d29cf5a5e0) RTTI typeinfo: itk::ANTSAffine3DTransform Reference Count: 3 Modified Time: 641 Debug: Off Object Name: Observers: none Matrix: 1.00704 -0.0474359 -0.0300319 -0.00426216 0.963137 0.00107288 0.038729 -0.0137559 0.974968 Offset: [6.30722, 2.03761, 4.32375] Center: [0.389297, -10.8862, -1.06683] Translation: [6.85839, 2.43609, 4.51528] Inverse: 0.992043 0.0492952 0.0305037 0.00443391 1.03848 -0.00100619 -0.0393447 0.0126938 1.02445 Singular: 0 Rotation: -0.00614875 -0.0192049 -0.00223314 0.999794 S1, S2, S3: 1.0078, 0.963, 0.97534 K1, K2, K3: -0.0516001, 0.00739577, -0.0113935

A=0.986243 -0.02932 -0.0164922 0.0413826 1.04453 0.00538632 0.0176219 0.0109714 1.03164

rotation R0.998962 -0.0421035 -0.0174028 0.0419162 0.999061 -0.0109899 0.0178491 0.010249 0.999788

upper R0.987268 0.0146892 0.00216463 0 1.0449 0.016649 0 0 1.03165

s=0.250068 u=0.00531118 v=-0.00881539 w0.0210107 r=0.999726 m_Rotation from vnl0.00531118 -0.00881539 0.0210107 0.999726 internal_transform: ANTSAffine3DTransform (0x55d29cf5a910) RTTI typeinfo: itk::ANTSAffine3DTransform Reference Count: 3 Modified Time: 648 Debug: Off Object Name: Observers: none Matrix: 0.986243 -0.02932 -0.0164922 0.0413826 1.04453 0.00538632 0.0176219 0.0109714 1.03164 Offset: [-2.16842, -3.71147, 1.71612] Center: [0.389297, -10.8862, -1.06683] Translation: [-1.837, -4.18591, 1.56979] Inverse: 1.01248 0.0282517 0.0160383 -0.0400255 0.956301 -0.00563281 -0.0168688 -0.0106527 0.969114 Singular: 0 Rotation: 0.00531118 -0.00881539 0.0210107 0.999726 S1, S2, S3: 0.987268, 1.0449, 1.03165 K1, K2, K3: 0.0148786, 0.00219255, 0.0159336

A=0.990046 0.0189837 0.0260862 -0.0184438 1.00396 0.0659593 -0.0143501 -0.0757684 0.962003

rotation R0.999722 0.0174833 0.015848 -0.018624 0.997014 0.0749478 -0.0144904 -0.0752221 0.997062

upper R0.990322 0.00137851 0.0109107 0 1.007 -0.00614544 0 0 0.964533

s=0.250194 u=-0.0375716 v=0.0075905 w-0.00903383 r=0.999224 m_Rotation from vnl-0.0375716 0.0075905 -0.00903383 0.999224 internal_transform: ANTSAffine3DTransform (0x55d29cf5ac40) RTTI typeinfo: itk::ANTSAffine3DTransform Reference Count: 3 Modified Time: 655 Debug: Off Object Name: Observers: none Matrix: 0.990046 0.0189837 0.0260862 -0.0184438 1.00396 0.0659593 -0.0143501 -0.0757684 0.962003 Offset: [-2.94248, 1.47502, -16.8846] Center: [0.389297, -10.8862, -1.06683] Translation: [-3.18084, 1.35432, -16.0248] Inverse: 1.00929 -0.0210409 -0.0259257 0.0174621 0.99056 -0.0683909 0.0164308 0.0777037 1.03372 Singular: 0 Rotation: -0.0375716 0.0075905 -0.00903383 0.999224 S1, S2, S3: 0.990322, 1.007, 0.964533 K1, K2, K3: 0.00139198, 0.0110173, -0.00610274

average 3D scale parameter [0]:1 0.990748 0.996347 1.01847 [1]:1 1.01897 0.991176 1.0136 [2]:1 1.0078 0.963 0.97534 [3]:1 0.987268 1.0449 1.03165 [4]:1 0.990322 1.007 0.964533 sum:w=5 4.99511 5.00242 5.0036 average 0.999021 1.00048 1.00072 average 3D shearing parameter [0]:1 0.0525209 -0.0139667 -0.0305691 [1]:1 -0.0199169 -0.00651959 0.0392031 [2]:1 -0.0516001 0.00739577 -0.0113935 [3]:1 0.0148786 0.00219255 0.0159336 [4]:1 0.00139198 0.0110173 -0.00610274 sum:w=5 -0.00272547 0.000119295 0.00707124 average -0.000545094 2.3859e-05 0.00141425 average 3D rotation parameter [0]:1 0.0111731 0.00247143 -0.0197961 0.999739 [1]:1 0.0276228 0.0163708 0.00930857 0.999441 [2]:1 -0.00614875 -0.0192049 -0.00223314 0.999794 [3]:1 0.00531118 -0.00881539 0.0210107 0.999726 [4]:1 -0.0375716 0.0075905 -0.00903383 0.999224 sum:w=5 0.00038666 -0.00158763 -0.000743818 4.99792 average 7.73321e-05 -0.000317526 -0.000148764 0.999585 average 3D translation parameter [0]:1 -5.19915 -0.836696 17.8728 [1]:1 3.08318 1.03966 -7.63824 [2]:1 6.85839 2.43609 4.51528 [3]:1 -1.837 -4.18591 1.56979 [4]:1 -3.18084 1.35432 -16.0248 sum:w=5 -0.27542 -0.192525 0.294766 average -0.055084 -0.0385051 0.0589531 average_iaffANTSAffine3DTransform (0x55d29cf49f00) RTTI typeinfo: itk::ANTSAffine3DTransform Reference Count: 2 Modified Time: 658 Debug: Off Object Name: Observers: none Matrix: 0.999021 -0.000246815 -0.000611539 -0.000297408 1.00048 0.00126018 0.00063467 0.000154552 1.00072 Offset: [-0.0580421, -0.0317767, 0.0611562] Center: [0.389297, -10.8862, -1.06683] Translation: [-0.055084, -0.0385051, 0.0589531] Inverse: 1.00098 0.000246843 0.000611387 0.000298355 0.999517 -0.00125848 -0.000634882 -0.000154523 0.999281 Singular: 0 Rotation: 7.73642e-05 -0.000317658 -0.000148825 1 S1, S2, S3: 0.999021, 1.00048, 1.00072 K1, K2, K3: -0.000545094, 2.3859e-05, 0.00141425

affine_outputMatrixOffsetTransformBase (0x55d29cf59aa0) RTTI typeinfo: itk::MatrixOffsetTransformBase<double, 3u, 3u> Reference Count: 2 Modified Time: 662 Debug: Off Object Name: Observers: none Matrix: 0.999021 -0.000246815 -0.000611539 -0.000297408 1.00048 0.00126018 0.00063467 0.000154552 1.00072 Offset: [-0.0580421, -0.0317767, 0.0611562] Center: [0.389297, -10.8862, -1.06683] Translation: [-0.055084, -0.0385051, 0.0589531] Inverse: 1.00098 0.000246843 0.000611387 0.000298355 0.999517 -0.00125848 -0.000634882 -0.000154523 0.999281 Singular: 0

wrote file to : /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0GenericAffine.mat Using double precision for computations. Input vector image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0warp.nii.gz Reference image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz

The composite transform comprises the following transforms (in order):

inverse of /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0GenericAffine.mat (type = MatrixOffsetTransformBase)

Default pixel value: 0 Interpolation type: LinearInterpolateImageFunction Output warped image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0warp.nii.gz /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0warp.nii.gz Max : [0.0891742, 0.181565, 0.00278459] Min : [0, 0, 0] Mean : [0.010026, 0.00955034, 0.00961539] Var : 0.000542484 SD : 0.0232913

shapeupdatetotemplate---warp each template by the resulting transforms /usr/local/ANTs/bin/antsApplyTransforms -d 3 --float 1 --verbose 1 -i /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz -o /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz -t [ /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0GenericAffine.mat,1 ] -t /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0warp.nii.gz -t /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0warp.nii.gz -t /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0warp.nii.gz -t /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0warp.nii.gz -r /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz

Using single precision for computations. Input scalar image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz Reference image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz

The composite transform comprises the following transforms (in order):
/media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0warp.nii.gz (type = DisplacementFieldTransform)
/media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0warp.nii.gz (type = DisplacementFieldTransform)
/media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0warp.nii.gz (type = DisplacementFieldTransform)
/media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0warp.nii.gz (type = DisplacementFieldTransform)
inverse of /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0GenericAffine.mat (type = MatrixOffsetTransformBase)

Default pixel value: 0 Interpolation type: LinearInterpolateImageFunction Output warped image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz

Done creating: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz Script executed in 190861 seconds 53h 1m 1s`

ANTsX / ANTs

Why is the execution time of antsMultivariateTemplateConstruction2.sh very slow #1280

Center of mass alignment using fixed image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz and moving image: /media/hwang/Disk1/brain_template_elderly/test//2000008.nii.gz (type = Euler3DTransform)

Total elapsed time: 9163 Using single precision for computations. Input scalar image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template02000008Repaired.nii.gz Reference image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz

/media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200000831Warp.nii.gz (type = DisplacementFieldTransform)

Elapsed time: 484.465 All_Command_lines_OK Using single precision for computations.

Center of mass alignment using fixed image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz and moving image: /media/hwang/Disk1/brain_template_elderly/test//2000013.nii.gz (type = Euler3DTransform)

Total elapsed time: 6688 Using single precision for computations. Input scalar image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template02000013Repaired.nii.gz Reference image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz

/media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_200001341Warp.nii.gz (type = DisplacementFieldTransform)

(금) 14:11:16 KST

(금) 14:11:40 KST

(금) 14:12:39 KST

inverse of /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0GenericAffine.mat (type = MatrixOffsetTransformBase)

Using single precision for computations. Input scalar image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz Reference image: /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0.nii.gz

inverse of /media/hwang/Disk1/brain_template_elderly/test/brain_template/age_test_T_template0GenericAffine.mat (type = MatrixOffsetTransformBase)