Parameter estimation for complex physical problems often suffers from finding ‘solutions’ that are not physically realistic. The PEUQSE software provides tools for finding physically realistic parameter estimates, graphs of the parameter estimate positions within parameter space, and plots of the final simulation results.
Simulated annealing is sometimes used in Gibbs sampling and should be added in for the doMetropolisHastings function's burn in. https://en.wikipedia.org/wiki/Simulated_annealing
Related: https://ieeexplore.ieee.org/abstract/document/8374537