Closed jtahir closed 2 years ago
You don't need to infer IBD if you only have parent offspring data. I recommend reading the guide and running through the tutorial: https://snipar.readthedocs.io/en/latest/guide.html https://snipar.readthedocs.io/en/latest/tutorial.html
On Mon, 5 Sept 2022 at 11:25, jtahir @.***> wrote:
Hi there I have a question. I have genetic data of female parent, F1s, but missing the male parent. How can I proceed to impute the missing parent data? Do i need to calculate IBDs first. My data is in the following format;
CHROM POS Parent 1 Parent2 F1_1 F1_2 ........F1_199 LG1 68111 aa ab aa ab .. LG29 17,858,85 ab aa aa aa
thanks
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Hi I am trying to run impute.py scrip on the following subset file but its not working. Could it be I don't have age or sex file for the siblings. https://drive.google.com/file/d/143TUSecFigU7KRZmU16Y7rx7tl8bQAlW/view?usp=sharing https://drive.google.com/file/d/143TUSecFigU7KRZmU16Y7rx7tl8bQAlW/view?usp=sharing
You need to have your genotypes in .bed or .bgen file format.
On Mon, 5 Sept 2022 at 12:08, jtahir @.***> wrote:
Hi I am trying to run impute.py scrip on the following subset file but its not working. Could it be I don't have age or sex file for the siblings.
https://drive.google.com/file/d/143TUSecFigU7KRZmU16Y7rx7tl8bQAlW/view?usp=sharing
https://drive.google.com/file/d/143TUSecFigU7KRZmU16Y7rx7tl8bQAlW/view?usp=sharing http://url
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Hi there I have a question. I have genetic data of female parent, F1s, but missing the male parent. How can I proceed to impute the missing parent data? Do i need to calculate IBDs first. My data is in the following format;
CHROM POS Parent 1 Parent2 F1_1 F1_2 ........F1_199 LG1 68111 A/A A/T A/C ......... A/A .. LG29 17,858,85 A/T A/A A/T ......... A/A
There are likely abxaa makers, or vice versa, but its also likely we have abxab calls thanks