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AlexandrovLab / SigProfilerSingleSample

SigProfilerSingleSample allows attributing a known set of mutational signatures to an individual sample. The tool identifies the activity of each signature in the sample and assigns the probability for each signature to cause a specific mutation type in the sample. The tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting.
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SigProfilerSingleSample not used by CNV signature #18

Closed Tina610 closed 2 years ago

Tina610 commented 2 years ago

Hi，I read the CNV signature paper(s41586-022-04738-6), I understand that computing CNV signature requires SigProfilerMatrixGenerator-->SigProfilerExtractor-->SigProfilerSingleSample. I don't know if I got that right...? The sigproSS created on "Nov 7 13:33:06 2018", may cannot run it with CNV signatures

marcos-diazg commented 2 years ago

Dear @Tina610,

Thanks for your interest in our tool! As mentioned in previous issues, we are in the process of retiring SigProfilerSingleSample, and we strongly recommend users to use our new SigProfilerAssignment tool, which has support for CNV mutational signatures assignment in the most recent v0.0.8.

I hope this helps, and please reopen the ticket if you have further questions.