AlexsLemonade / OpenPBTA-analysis

The analysis repository for the Open Pediatric Brain Tumor Atlas Project
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Update GSVA analysis and figure #1338

Closed sjspielman closed 2 years ago

sjspielman commented 2 years ago

Closes #1337

This PR updates the GSVA analysis and associated manuscript figure.

The analysis itself is updated to consider cancer_group instead of display_group, and associated results as well as README are updated accordingly. Re-running this module also updated some of the retained results because the module hadn't been run with the most recent data. There's a teeny bit of unneeded updates -

The figure script is updated to output a new GSVA heatmap with a cancer_group annotation as well as an associated legend. The final plot will therefore have separate legends for A and B.

Question: Do we want to remove "Other" from the heatmap, or keep it at the end (as is currently there)?

jharenza commented 2 years ago

Question: Do we want to remove "Other" from the heatmap, or keep it at the end (as is currently there)?

We can remove other - those results won't be super meaningful!

jharenza commented 2 years ago

going to merge and update manuscript results based on this