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AllenInstitute / coupledAE-patchseq

Multimodal data alignment and cell type analysis with coupled autoencoders.
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question about sPCs computing and selection #2

Closed hongruhu closed 3 years ago

hongruhu commented 3 years ago

Hi, I was wondering when the sPCs were computed, (see spiking_width as an example) does this mean there are 6 sets of sPCs computed from the 6 chunks respectively? Just like, compute 1st set of sPCs from [0:50] timepoints, and 2nd set from [51:100] timepoints,..., so by the end, we will get 6 independent sets of sPCs potentially for reconstruction for 

"spiking_width": {
        "n_components": 3,
        "nonzero_component_list": [150, 100, 112],
        "use_corr": false,
        "range": [0, 50, 100, 150, 200, 250]
    }

If that's the case, I was wondering how would you selected the sPCs for the CoupledAE model? As for the spiking-width, there were only two sPCs selected (based on the accuracy maybe? Extended Data Fig. 7), I was just wonderig are these two sPCs from the same chunk?

Thanks!

hongruhu commented 3 years ago

this question has been answered in another repo, thanks.