Problem:
addresses step 4 in Merge
For each pair, compute differentially expressed genes and score
Solution:
Reproduce de_stats() from R, except that here it only returns the de score for the cluster pair as suggested by the merging module
Validation:
unit tests
Note:
I have added qdiff as part of de_pair_chisq . This way we do not need to modify de_stats.
I have dropped the wrapper function that computed and returned all the score metrics because it seemed redundant.
Instead I propose usage as shown in test_calc_de_score_for_pair that provides the up/down genes and scores. I propose to directly include those calls into get_de_scores_for_pairs
Problem: addresses step 4 in Merge For each pair, compute differentially expressed genes and score
Solution: Reproduce de_stats() from R, except that here it only returns the de score for the cluster pair as suggested by the merging module
Validation: unit tests
Note: I have added qdiff as part of
de_pair_chisq. This way we do not need to modify de_stats.I have dropped the wrapper function that computed and returned all the score metrics because it seemed redundant. Instead I propose usage as shown in
test_calc_de_score_for_pairthat provides the up/down genes and scores. I propose to directly include those calls intoget_de_scores_for_pairs