AllenInstitute / transcriptomic_clustering

improved clustering pipeline for transcriptomic data
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draft differential expression using moderated t-test #90

Closed MatthewAitken closed 3 years ago

MatthewAitken commented 3 years ago

see http://confluence.corp.alleninstitute.org/display/IT/Limma+DE for references

as of commit 4153cd8, the code is correct up to and including p_val calculation. The p_adj doesn't match R, and I believe something is funky with the de_param filtering in the R test script.

R test script: https://gist.github.com/MatthewAitken/5feb6c1caca5d71ae71dd043c8518de6