after running AA and AC,I konw I got some amplication with eccDNA. However, in fact, a cycle defined in one amplicon of AA may contain multiple segments. However, when we run Circle-Map on CIRCLE-seq data, we usually get a self closed cycle with only one segment. What data should I use to compare with the circleseq data?
This is a very hard question for me to answer without seeing the data itself, sorry. Please feel free to email me if you would like to discuss further.
after running AA and AC,I konw I got some amplication with eccDNA. However, in fact, a cycle defined in one amplicon of AA may contain multiple segments. However, when we run Circle-Map on CIRCLE-seq data, we usually get a self closed cycle with only one segment. What data should I use to compare with the circleseq data?