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AmsterdamUMC / AmsterdamUMCdb

AmsterdamUMCdb - Freely Accessible ICU database. Please access our Open Access manuscript at https://doi.org/10.1097/CCM.0000000000004916
https://amsterdammedicaldatascience.nl/
MIT License
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Teasing out analgesics from the sedatives/analgesics/CZS drug category #78

Closed pmugambi closed 3 weeks ago

pmugambi commented 1 year ago

When looking through analgesics in the dataset, I noticed they are grouped with sedatives and CZS (which I'm not sure what it stands for). What's the reason for this? Also, is there a direct way to tease out which drugs are analgesics?

patrickthoral commented 1 year ago

CZS stands for Centraal Zenuwstelsel (central nervous system). The reason for this is that there is no 100% clear distinction between the two (i.e. analgosedatives) and there is considerable overlap between general anesthestetics and analgesics. For the most common used analgesics, you could use the vocabulary_concept_code starting with N02 and some of them are also in NO1H. But some medication have analgesic properties and are thus used for that indication e.g. C02AC01 and N01AX14. Official documentation on WHO could also be used for string matching for a complete list, but those we use commonly have already been mapped in the dictionary using the above mentioned codes.