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AndrewCRMartin / absplit

Code to split an antibody PDB file into Fv fragments with their antigens
GNU General Public License v3.0
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Special case 4hjj #9

Closed AndrewCRMartin closed 1 year ago

AndrewCRMartin commented 2 years ago

special case: 4hjj_1P 4HJJ is a Dual Variable Domain Immunoglobulin (DVD-Ig)

pdb4hjj_1P.cho variable domain CDR is not interacting with the antigen.

In the original PDB file of 4HJJ, based on its structure, H126-H246 and L114-L224 looks like the second variable domain and is interacting with the antigen, is the correct variable domain to trauncate.

AndrewCRMartin commented 2 years ago

special_case-4hjj.pdf

AndrewCRMartin commented 1 year ago

I believe this is now correct.