Anthony-Nolan / Atlas.Auto.Tests

Automated end-to-end test framework for the Atlas search algorithm.
GNU General Public License v3.0
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Search tests: matching donor HLA should be ambiguous resolution #45

Open zabeen opened 5 months ago

zabeen commented 5 months ago

Currently matching donor is created using exact same high res phenotype as patient HLA.

It would be a better test of underlying infrastructure/code, especially HLA metadata dictionary and match prediction, if the donor HLA had some ambiguity.

The easiest thing is to convert all the allele typings to XX codes. It shouldn't impact match probabilities as auto tests use a small curated set of haplotype frequencies, so the XX donor should still only be explained by the same two haplotypes.