Closed zabeen closed 1 year ago
Results files have been generated with the required mismatch counts. Still to-do: write code to analyse the results.
Run on Atlas v1.6.0, AN DEV, master commit 3b265116
, against v3.50.0 of IMGT/HLA nomenclature files
Report of discrepant results - generated using new functions added to Atlas.ManualTesting
.
Summary:
B*51:XX
vs. *53:XX
, because B*51:42P
includes *53:62
A*02:XX
vs. *74:XX
, because A*02:65P
includes *74:21
B*39:XX
vs. *38:XX
, because expanded B*38:XX
includes four alleles that have been renamed to B*39
alleles (see #967 for more info).The final discrepant case (B39:XX vs. 38:XX) has been referred to an Anthony Nolan clinical scientist to determine if such a match is clinically valid or not.
Run on Atlas v1.6.0, AN DEV, master commit e9e19afa
, against v3.50.0 of IMGT/HLA nomenclature files
Report of discrepant results - generated using new functions added to Atlas.ManualTesting
.
Source data: https://pubmed.ncbi.nlm.nih.gov/27219013/
Exercise requires comparison of every possible patient and donor combination in order to generate match counts and antigen/allele match counts. Cannot run the test patients as search requests as Atlas will not allow 0/10 searches or even 1/10. Will instead use the batch scoring endpoint to generate the necessary counts, as scoring depends on the same logic as matching.
Can use AN Dev as the donor data will be submitted within the scoring request itself, and so no test donor data needs to be uploaded to the donor store.