Open annaquaglieri16 opened 5 years ago
@annaquaglieri16, hello!
It seems that this is an old problem for a very rare case when VD>DP (https://github.com/AstraZeneca-NGS/VarDictJava/issues/92). As a result, AF becomes > 1. Could you please share a small part of BAM file where it occurs? It will be very helpful if it is possible because your case is very good for debugging due to the small number of reads covers this variant.
Thank you a lot!
Thanks @PolinaBevad ,
Unfortunately I cannot right now, since they are patient with restricted access. I am going to check with my supervisor.
Cheers, Anna
Hi there, Maybe I am not clear about what the field
AF
represents but, in the header, it is defined as:##INFO=<ID=AF,Number=1,Type=Float,Description="Allele Frequency">
However, I get values > 1.
How is that possible?
Thanks,
Anna